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Ampicillin

About

Ampicillin belongs to a class of medicines called penicillin antibiotics. Ampicillin is commonly used to treat various bacterial infections of the lungs, skin, stomach, and kidneys as well as sexually transmitted infections like gonorrhoea. A bacterial infection occurs when harmful bacteria enter the body, multiply and cause infection. It can infect any part of the body and multiple very quickly.

Ampicillin contains Ampicillin that works against various types of bacteria. It inhibits the process of bacterial cell wall synthesis that is required for its survival. Thus, Ampicillin kills bacteria and prevents the growth of bacterial infection. 

Ampicillin should be taken 30 minutes before food or 2 hours after food, on an empty stomach. Ampicillin may cause certain common side effects such as injection site reactions, rash, vomiting, allergic reaction, vaginal itching, or discharge, nausea, and diarrhea. Most of these side effects are mild and subside over time. However, if these persist contact your doctor immediately.

Ampicillin should be avoided if you are allergic to it, or other penicillin antibiotics. Also, inform your doctor if you have any kidney or liver problems. Pregnant and nursing mothers should consult a doctor before Ampicillin treatment. Birth control pills may not work effectively while using this medication. So, speak to your doctor about using non-hormonal birth control to avoid pregnancy.

Uses of Ampicillin

Bacterial infections

Medicinal Benefits

Ampicillin is a broad-spectrum penicillin antibiotic that is effective against a wide range of bacterial infections. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. Ampicillin mainly kills the bacteria and prevents the growth of bacterial infection. It is used in the treatment of bacterial infections such as meningitis, kidney infections, gonorrhoea, pneumonia, or infections of the intestines or stomach. Ampicillin is also used in combination with other penicillin antibiotics called flucloxacillin and the combination is known as co-fluampicil.    

Directions for Use

Tablet/Capsule: Take Ampicillin on an empty stomach at least 30 minutes before or 2 hours after food to avoid stomach upset. Swallow Ampicillin as a whole with a glass of water. Do not break, crush or chew it. Suspension: Before consuming shake the bottle well. It should be taken by mouth using the measuring cup provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ampicillin

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Vaginal itching or discharge

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor immediately if you have any hypersensitive reactions, severe stomach pain, pale skin, short of breath after taking Ampicillin. Also, Let your doctor know if you ever had diabetes, asthma, kidney disease, or antibiotics-induced diarrhea. This medicine may lower the efficiency of oral birth control pills or contraceptive devices. Ampicillin may alter test results with certain medical tests. Tell your doctor before undergoing those tests that you are using Ampicillin.

Drug Interactions

Drug-Drug Interaction: Ampicillin should not be given with Typhoid vaccine (live), cephalosporin antibiotics such as cefaclor, cefadroxil, cefazolin, cefixime, cefpodoxime, cefprozil, cephalexin; allopurinol/ probenecid (used to treat gout).

Drug-Food Interaction:  Avoid consumption of alcohol while taking Ampicillin as it can cause serious side effects.   

Drug-Disease Interaction: Ampicillin should not be used in patients with Renal dysfunction, colitis (inflammation of the colon) and hemodialysis.

 

Drug-Drug Interactions Checker List:

  • TYPHOID VACCINE
  • CEFADROXIL
  • CEFACLOR
  • CEFAZOLIN
  • CEFIXIME
  • CEFPODOXIME
  • CEFPROZIL
  • CEPHALEXIN
  • ALLOPURINOL
  • PROBENECID
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol while taking treatment with Ampicillin.

    • Safety Warning

      Pregnancy

      caution

      Ampicillin should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or planning a pregnancy.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking Ampicillin; your doctor will decide whether Ampicillin can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      safe if prescribed

      It is safe to drive a motor vehicle after using Ampicillin.

    • Safety Warning

      Liver

      safe if prescribed

      Ampicillin can be safely used in case of liver disease if prescribed by your doctor.

    • Safety Warning

      Kidney

      caution

      Ampicillin should be used under caution in patients with kidney disease. Inform your doctor if you have kidney problems. Your doctor will prescribe only if the benefits outweigh the risks. If prescribed, the dose may be adjusted by your doctor based on your health condition.

    • Safety Warning

      Children

      safe if prescribed

      Ampicillin can be given safely to children, dose to be adjusted and recommended by a child specialist only.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Diarrhea may happen as a side effect. Taking probiotics after completing treatment with Ampicillin may help. Talk to your doctor if you notice blood stools or develop stomach cramps.
    • Drink plenty of fluids to avoid an upset stomach and hydrate your body.
    • Avoid intake of alcoholic beverages with Ampicillin as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Ampicillin in fighting off infections.
    • Maintain good hygiene and avoid contaminated or processed food.
    • Include more fibre enriched food like whole-grain bread, and brown rice in your diet, as it can be easily digested by your gut bacteria which helps stimulate their growth. 
    • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Ampicillin.

    Special Advise

    • Even if you feel better after treatment with Ampicillin, do not stop taking it. This might cause the symptoms to reappear and will make the infection difficult to treat due to antibiotic resistance.
    • Make sure you drink plenty of fluids when you are sick. This will in general help you clear out the infection faster, protect you from dehydration, and will help you overcome some unpleasant side effects of taking Ampicillin.
    • Stop taking Ampicillin and consult your doctor immediately if you develop any allergic reactions such as itching, skin rash, swelling of the face, throat, tongue, and, breathing difficulties.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any part of the body and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections. Ampicillin does not work against infections caused by viruses, including cold and flu.

    FAQs

    Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhea as it may help in increasing the number of good bacteria in the intestine which aids in digestion.

    Ampicillin contains ampicillin, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

    Yes, Ampicillin may be used to treat lung infections caused by bacteria. Ampicillin is an antibiotic that kills bacteria and prevents the spread of infection.

    No, this is an antibiotic medication. You need to complete the full course even if you start to feel better to prevent the return of infection and resistance to Ampicillin.

    Ampicillin does not work against viral infection. So, it should not be taken to treat the common cold or cough. Consult your doctor if you have these symptoms.

    Use of Ampicillin may lower the efficiency of birth control pills. Ask your doctor about using other contraception devices like diaphragm, condom, spermicide, copper T, etc with Ampicillin.

    Ampicillin may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Ampicillin and consult a doctor immediately

    Available Medicines for

    Ampicillin

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