Atorvastatin+metoprolol+ramipril
About
Atorvastatin+metoprolol+ramipril is a combination medicine used to treat hypertension (high blood pressure) and reduce cholesterol levels. Also, it reduces the risk of heart attack or stroke. Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.
Atorvastatin+metoprolol+ramipril contains Atorvastatin (statin), Metoprolol (beta-blocker) and Ramipril (ACE inhibitor). Atorvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by lowering the excess cholesterol deposition in the major blood vessels of the brain and heart. Metoprolol acts by inhibiting beta receptors in the heart, causing the heart to beat more slowly and with less power. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Ramipril works by blocking the angiotensin-converting enzyme (ACE) in the body. Thus, it reduces the production of angiotensin II, which causes constriction and narrowing of blood vessels. This allows the blood vessels to relax and widen and lower blood pressure.
Take Atorvastatin+metoprolol+ramipril as prescribed by your doctor. You are advised to take Atorvastatin+metoprolol+ramipril for as long as your doctor has recommended it based on your medical condition. Sometimes, Atorvastatin+metoprolol+ramipril may cause common side effects such as tiredness, dizziness, slow heartbeat, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), and cold hands and feet. Most of these side effects of Atorvastatin+metoprolol+ramipril do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Atorvastatin, metoprolol, ramipril or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Atorvastatin+metoprolol+ramipril. Avoid drinking alcohol with Atorvastatin+metoprolol+ramipril as it may cause tiredness. Drive only if you are alert, as Atorvastatin+metoprolol+ramipril may cause dizziness or tiredness. If you are undergoing dialysis or any other type of blood filtration, inform your doctor before taking Atorvastatin+metoprolol+ramipril.
Uses of Atorvastatin+metoprolol+ramipril
Medicinal Benefits
Atorvastatin+metoprolol+ramipril contains Atorvastatin, Metoprolol and Ramipril, used to treat hypertension (high blood pressure) and reduce cholesterol levels. Also, it reduces the risk of heart attack or stroke. Atorvastatin decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by lowering the excess cholesterol deposition in the major blood vessels of the brain and heart. Metoprolol makes the heart to beat slowly and with less force. Thus, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Ramipril works by decreasing the production of certain substances in the body that could raise blood pressure. Thus, it lowers blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood around the body.
Directions for Use
Storage
Side Effects of Atorvastatin+metoprolol+ramipril
- Tiredness
- Dizziness
- Slow heartbeat
- Nausea
- Headache
- Orthostatic hypotension (low blood pressure when standing up from sitting or lying position)
- Cold hands and feet
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Atorvastatin, metoprolol, ramipril or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Atorvastatin+metoprolol+ramipril. Avoid drinking alcohol with Atorvastatin+metoprolol+ramipril as it may cause tiredness. Drive only if you are alert, as Atorvastatin+metoprolol+ramipril may cause dizziness or tiredness. If you are undergoing dialysis or any other type of blood filtration, inform your doctor before taking Atorvastatin+metoprolol+ramipril. If you are about to undergo surgery where an anaesthetic is used, please tell your doctor that you are taking Atorvastatin+metoprolol+ramipril. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Atorvastatin+metoprolol+ramipril.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you are taking immunosuppressant (ciclosporin), antibiotics (clarithromycin, telithromycin, erythromycin, rifampin, fusidic acid), antifungals (ketoconazole, itraconazole, voriconazole, fluconazole, posaconazole), other cholesterol-lowering medicines (colestipol, gemfibrozil), medicines used to regulate heart rhythm (digoxin, verapamil, amiodarone), antidepressants (fluoxetine, paroxetine, sertraline), other medicines used to treat high blood pressure, ergot alkaloids and non-steroidal anti-inflammatory drugs (ibuprofen, aspirin).
Drug-Food Interaction: Avoid taking more than one or two small glasses of grapefruit juice per day, as large quantities of grapefruit juice can change the effects of Atorvastatin. Atorvastatin+metoprolol+ramipril may interact with St. John’s wort (herbal supplement used to treat depression). Also, avoid alcohol consumption as it may increase tiredness.
Drug-Disease Interaction: If you have phaeochromocytoma (tumour in the adrenal gland), asthma, severe skin problems, slow or irregular heartbeat, diabetes, hypothyroidism (under-active thyroid gland), severe respiratory failure, very poor blood circulation in your limbs, muscle problems, liver, heart or kidney problems, inform your doctor before taking Atorvastatin+metoprolol+ramipril.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption while taking Atorvastatin+metoprolol+ramipril as it may increase tiredness.
Pregnancy
consult your doctorAtorvastatin+metoprolol+ramipril is usually not recommended for pregnant women. Please inform your doctor if you are pregnant or planning for pregnancy before taking this medicine.
Breast Feeding
consult your doctorAvoid taking Atorvastatin+metoprolol+ramipril without consulting your doctor, if you are breastfeeding.
Driving
cautionAtorvastatin+metoprolol+ramipril may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Atorvastatin+metoprolol+ramipril.
Liver
consult your doctorIf you have a history of or are suffering from liver disease, inform your doctor before taking Atorvastatin+metoprolol+ramipril. Your doctor may adjust the dose if required based on your condition.
Kidney
consult your doctorIf you have Kidney problems, inform your doctor before taking Atorvastatin+metoprolol+ramipril. Your doctor may adjust the dose if required based on your condition.
Children
consult your doctorAtorvastatin+metoprolol+ramipril is not recommended for use in children below ten years. Please consult your doctor. Your doctor may prescribe a suitable dose based on the age, body weight and clinical condition of your child.
Habit Forming
Diet & Lifestyle Advise
- Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
- Do regular exercises such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes daily.
- Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
- Maintain a diet rich in vegetables, fruits, and whole grains, and cut down on beverages and processed and sugary foods.
- Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
- Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil, which may help lower high blood pressure.
- Quit smoking and avoid the consumption of alcohol.
Special Advise
- Based on your health history, your doctor may recommend certain blood tests while taking Atorvastatin+metoprolol+ramipril to monitor blood sugar, liver, heart, kidney and thyroid function.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. Normal blood pressure lies between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.
Hyperlipidemia (high cholesterol): It occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol.
FAQs
Atorvastatin+metoprolol+ramipril contains Atorvastatin, Metoprolol and Ramipril. Atorvastatin decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Metoprolol makes the heart to beat slowly and with less force. Thus, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Ramipril works by decreasing the production of certain substances in the body that could raise blood pressure. Thus, it lowers blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood around the body.
Atorvastatin+metoprolol+ramipril may cause sudden dizziness when standing up from sitting or lying position. Therefore, to avoid such effects, standing up slowly from a sitting or lying position is advised.
Atorvastatin+metoprolol+ramipril should be used with caution in diabetic patients as it may increase blood sugar levels. Therefore, if you have diabetes, inform your doctor before taking Atorvastatin+metoprolol+ramipril. Also, regular monitoring of blood sugar levels is recommended while taking Atorvastatin+metoprolol+ramipril.
