Azelastine Hydrochloride+fluticasone Propionate
About
Azelastine Hydrochloride+fluticasone Propionate belongs to the class of medications called 'anti-allergic' primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.
Azelastine Hydrochloride+fluticasone Propionate is a combination of two drugs, namely: Fluticasone propionate (corticosteroid) and Azelastine hydrochloride (antihistamine/antiallergic). Fluticasone propionate belongs to the class of corticosteroids that works by acting inside the cells of the nasal lining and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose and sinus discomfort. On the other hand, Azelastine hydrochloride belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
Use Azelastine Hydrochloride+fluticasone Propionate as advised by your doctor. Your doctor will recommend how often you use Azelastine Hydrochloride+fluticasone Propionate based on your medical condition. Some people may experience certain common side effects such as headache, taste changes or nose bleeds. Most of these side effects of Azelastine Hydrochloride+fluticasone Propionate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Azelastine Hydrochloride+fluticasone Propionate or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Azelastine Hydrochloride+fluticasone Propionate. Azelastine Hydrochloride+fluticasone Propionate is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds or increased drowsiness, stop using Azelastine Hydrochloride+fluticasone Propionate and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Azelastine Hydrochloride+fluticasone Propionate may weaken the immune system causing infections easily. Keep your doctor informed about your health condition and medications to rule out any interactions.
Uses of Azelastine Hydrochloride+fluticasone Propionate
Medicinal Benefits
Azelastine Hydrochloride+fluticasone Propionate is a combination of two drugs, namely: Fluticasone propionate and Azelastine hydrochloride, used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose or watery eyes. Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining. It stops the release of certain chemicals in the body that cause inflammatory reactions, thereby providing relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine hydrochloride belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together Azelastine Hydrochloride+fluticasone Propionate relieves allergic symptoms, including seasonal allergies and reduces inflammation of nasal passage.
Directions for Use
Storage
Side Effects of Azelastine Hydrochloride+fluticasone Propionate
- Headache
- Taste changes
- Nose bleeds
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Azelastine Hydrochloride+fluticasone Propionate or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Azelastine Hydrochloride+fluticasone Propionate. Azelastine Hydrochloride+fluticasone Propionate is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds or increased drowsiness, stop using Azelastine Hydrochloride+fluticasone Propionate and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Azelastine Hydrochloride+fluticasone Propionate may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers or sores inside the nose, inform your doctor before using Azelastine Hydrochloride+fluticasone Propionate.
Drug Interactions
Drug-Drug Interactions: Azelastine Hydrochloride+fluticasone Propionate may interact with antidepressants (duloxetine, escitalopram), anticonvulsants (pregabalin), HIV/AIDS drug (ritonavir), antifungals (ketoconazole, fluconazole, itraconazole) and anti-allergy drugs (cetirizine).
Drug-Food Interactions: Azelastine Hydrochloride+fluticasone Propionate may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Azelastine Hydrochloride+fluticasone Propionate as it may lead to adrenal insufficiency and Cushing’s syndrome. Also, avoid consumption of alcohol with Azelastine Hydrochloride+fluticasone Propionate as it may cause increased drowsiness, dizziness, and impairment of judgement and thinking.
Drug-Disease Interactions: If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers or sores inside the nose, inform your doctor before using Azelastine Hydrochloride+fluticasone Propionate.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consumption of alcohol with Azelastine Hydrochloride+fluticasone Propionate as it may increase adverse effects. Please consult a doctor before consuming alcohol with Azelastine Hydrochloride+fluticasone Propionate.
Pregnancy
cautionThe safety of Azelastine Hydrochloride+fluticasone Propionate in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionPlease consult your doctor before using Azelastine Hydrochloride+fluticasone Propionate if you are breastfeeding.
Driving
cautionAzelastine Hydrochloride+fluticasone Propionate may cause drowsiness in some people. Therefore, drive only if you are alert after using Azelastine Hydrochloride+fluticasone Propionate.
Liver
cautionLet your doctor know if you have any history of liver diseases before using Azelastine Hydrochloride+fluticasone Propionate.
Kidney
cautionLet your doctor know if you have any history of kidney diseases before using Azelastine Hydrochloride+fluticasone Propionate.
Children
cautionAzelastine Hydrochloride+fluticasone Propionate is not recommended for children below 6 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
- Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from a runny nose, cough, and sneezing.
- The immune system is affected by stress and raises the risk of being sick. Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress.
- It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, and certain food items that are known to cause allergies to you.
- Maintain personal hygiene and keep your surroundings clean.
Special Advise
Certain blood tests are recommended while using Azelastine Hydrochloride+fluticasone Propionate to monitor serum cortisol levels as Azelastine Hydrochloride+fluticasone Propionate may increase these levels.
Patients Concern
Disease/Condition Glossary
Allergy: It is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to the body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.
FAQs
Azelastine Hydrochloride+fluticasone Propionate contains Fluticasone propionate and Azelastine hydrochloride. Fluticasone propionate works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine hydrochloride is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
You are recommended to avoid using grapefruit and grapefruit juice with Azelastine Hydrochloride+fluticasone Propionate as they may lead to adrenal insufficiency and Cushing’s syndrome.
Azelastine Hydrochloride+fluticasone Propionate may cause drowsiness in some people, especially in people consuming alcohol with Azelastine Hydrochloride+fluticasone Propionate. Therefore, avoid driving if you feel drowsy after using Azelastine Hydrochloride+fluticasone Propionate.
You are not recommended to take more than the prescribed dose of Azelastine Hydrochloride+fluticasone Propionate or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while using Azelastine Hydrochloride+fluticasone Propionate, please consult a doctor immediately.
Azelastine Hydrochloride+fluticasone Propionate is not intended for the treatment of asthma attacks. Azelastine Hydrochloride+fluticasone Propionate is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.
You should avoid using Azelastine Hydrochloride+fluticasone Propionate and consult a doctor before using Azelastine Hydrochloride+fluticasone Propionate if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.
