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Azelnidipine

About

Azelnidipine belongs to a class of anti-hypertensive drugs primarily used to treat hypertension (high blood pressure). Hypertension (high blood pressure) is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes high. The higher the blood pressure, the harder the heart pumps blood.

Azelnidipine contains Azelnidipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Azelnidipine is taken dose and duration as advised by the doctor. Azelnidipine may cause common side effects such as headaches, dizziness, swelling, and weakness. Most of these side effects do not require medical attention and usually resolve after some time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Pregnant or breastfeeding women should consult their doctor for advice before taking Azelnidipine. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking Azelnidipine for as long as your doctor has advised. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.

Uses of Azelnidipine

Hypertension (High blood pressure)

Medicinal Benefits

Azelnidipine contains Azelnidipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Azelnidipine

  • Headache
  • Fast heart rate
  • The feeling of a fast or uneven heartbeat (palpitations)
  • Sudden reddening of your face
  • Neck or upper chest (flushing)
  • Ankle swelling

In-Depth Precautions and Warning

Drug Warnings

Do not stop taking Azelnidipine without doctor advice. It is advised to continue taking Azelnidipine for as long as it has been prescribed by the doctor. Sudden stopping of Azelnidipine may cause changes in your blood pressure. Consult your doctor before using Azelnidipine if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.

Drug Interactions

Drug-Drug Interactions: Azelnidipine may have an interaction with antifungal agents (Itraconazole, Miconazole), HIV Protease Inhibitors (Ritonavir, Saquinavir, Indinavir), anti-epileptic (Phenytoin, Phenobarbital), a medicine used to lower cholesterol (Simvastatin), a medicine used to treat heart failure and abnormal heart rhythms (Digoxin), and antibiotic (Rifampicin).

Drug-Food Interactions: Due to the increased risk of severe side effects, grapefruit juice should not be consumed when taking Azelnidipine. Dizziness, headaches, fainting, and other adverse effects are possible.

Drug-Disease Interactions: Inform your doctor before taking the Azelnidipine if you have had serious liver and kidney dysfunction.

Drug-Drug Interactions Checker List:

  • ITRACONAZOLE
  • MICONAZOLE
  • RITONAVIR
  • SAQUINAVIR
  • INDINAVIR
  • PHENYTOIN
  • PHENOBARBITAL
  • SIMVASTATIN
  • DIGOXIN
  • RIFAMPICIN

    • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is advised to limit alcohol intake since alcohol consumption with Azelnidipine may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.

    • Safety Warning

      Pregnancy

      caution

      There is no substantial research yet on using Azelnidipine in pregnant women. Consult your doctor if you have any concerns.

    • Safety Warning

      Breast Feeding

      caution

      There is no substantial research yet on using Azelnidipine in breastfeeding/nursing mothers. Consult your doctor if you have any concerns.

    • Safety Warning

      Driving

      caution

      It is not known whether Azelnidipine alters the ability to drive. Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

    • Safety Warning

      Liver

      caution

      Please consult your doctor if you have any concerns regarding using Azelnidipine in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor if you have any concerns regarding using Azelnidipine in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Children

      caution

      There is limited information available on the usage of Azelnidipine in children. Please consult your doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
    • Keep your weight under control with a BMI of 19.5-24.9.
    • Avoid chronic stress as it can raise your blood pressure.
    • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
    • Be mindful of salt; consume no more than 2,300 mg each day.
    • Limit or avoid alcohol consumption.
    • Quitting smoking is the best strategy to lower the risk of heart disease.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

    FAQs

    Azelnidipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure.

    No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

    Please do not stop using Azelnidipine without consulting your doctor on your own. Continue using Azelnidipine for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Azelnidipine.

    Azelnidipine is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

    Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

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