Bamlanivimab+etesevimab
About Bamlanivimab+etesevimab
Bamlanivimab+etesevimab belongs to the group of monoclonal antibodies used in the post-exposure prevention and treatment of mild to moderate respiratory illness caused by COVID-19. Bamlanivimab+etesevimab is used in non-hospitalised cases of COVID-19 that are at risk of progressing to severe disease. Coronavirus disease is an infectious disease caused by SARS-CoV-2. It can range from a mild cold to a serious form of pneumonia.
Bamlanivimab+etesevimab contains Bamlanivimab and Etesevimab. Bamlanivimab+etesevimab works by using monoclonal proteins to imitate the natural defence mechanisms of the body. It blocks the spike protein of the virus from attaching to the human receptor cell, thereby arresting the progress of the disease.
Bamlanivimab+etesevimab will be administered by a qualified healthcare professional. Do not self-administer. Bamlanivimab+etesevimab may cause certain common side effects such as nausea, headache, pain and soreness at the injection site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.
It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed if you suffer from HIV, asthma, obesity, cancer, liver disease, kidney problems, heart disease, neurodevelopmental disorders, sickle cell disease, gastrostomy, tracheostomy or positive pressure ventilation. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding. Avoid Bamlanivimab+etesevimab use with alcohol.
Uses of Bamlanivimab+etesevimab
Medicinal Benefits
Bamlanivimab+etesevimab is a monoclonal antibody used in the post-exposure prophylaxis and treatment of mild to moderate disease caused by SARS-CoV-2. Bamlanivimab+etesevimab contains Bamlanivimab and Etesevimab. Bamlanivimab+etesevimab works by using monoclonal proteins to imitate the natural defence mechanisms of the body. The COVID virus contains a capsid with spike proteins, through which it penetrates the body to cause infection. Bamlanivimab+etesevimab binds to the spike protein of the virus. Bamlanivimab blocks the spike protein of the virus from attaching to the human receptor cell, thereby arresting the progress of the disease. Etesevimab also binds to a protein on the receptor cell, thereby blocking viral entry. However, it binds on a different but overlapping site and augments the response of Bamlanivimab. Hence, Bamlanivimab+etesevimab is synergistic in combination and finds use in preventing the progression of mild to moderate covid cases to severe cases requiring hospitalisation.
Directions for Use
Storage
Side Effects of Bamlanivimab+etesevimab
- Nausea
- Vomiting
- Diarrhoea
- Redness, Soreness and Pain at the injection site
- Chills
- Fever
Drug Warnings
It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed if you suffer from HIV, asthma, cancer, liver disease, kidney problems, heart disease, neurodevelopmental disorders, sickle cell disease, gastrostomy, tracheostomy or positive pressure ventilation. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor especially if you are on any radiotherapy, immunosuppressant drugs, blood thinners or any other medicines or herbs. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding. Bamlanivimab+etesevimab is not meant for use as vaccination. Bamlanivimab+etesevimab is not meant for use in severe hospitalised cases or in patients requiring high flow oxygen or mechanical ventilation as it may lead to worsened outcomes.
Drug Interactions
Drug-Drug Interactions: No interactions found.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: No interactions found.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is not recommended to consume alcohol with Bamlanivimab+etesevimab. Please consult your doctor if you have any concerns.
Pregnancy
cautionNot enough studies exist to ascertain the effect of Bamlanivimab+etesevimab on pregnancy. Please consult your doctor if you have any concerns.
Breast Feeding
cautionNot enough studies exist to ascertain the effect of Bamlanivimab+etesevimab on nursing. Please consult your doctor in case of any concerns.
Driving
cautionIt is not known if Bamlanivimab+etesevimab affects your ability to drive. Drive only if you are alert after taking Bamlanivimab+etesevimab.
Liver
cautionExercise caution before using Bamlanivimab+etesevimab in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
cautionExercise caution before using Bamlanivimab+etesevimab in case of established kidney disease. Please consult your doctor to address any concerns.
Children
safe if prescribedPlease consult your doctor if you have any concerns. Your doctor will determine the dose and duration based on your child's condition.
Habit Forming
Diet & Lifestyle Advise
- Keep a healthy state of mind. Fear is one of the biggest causes of decreased immunity. See a therapist when you feel overwhelmed.
- Meditation, music and yoga have also proven very effective in helping with mental health.
- Keep yourself at a safe distance from people.
- Always sneeze or cough into your elbow and keep a handkerchief on you.
- Wash your hands with soap and water and keep yourself clean.
- Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.
- Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.
- Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health.
- Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.
- Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.
- Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.
Special Advise
- In case of a fever or rash following Bamlanivimab+etesevimab, do not use any antipyretic or anti-allergic medicines without consulting the doctor.
Patients Concern
Disease/Condition Glossary
Coronavirus Disease: Coronavirus disease is an infection caused by the SARS-CoV-2 virus. It can range from a mild cold, cough and fever to full-blown pneumonia. Coronavirus belongs to a group of RNA viruses and has crown-like projections on the surface of the pathogen. The virus transmits through droplets generated from an infectious person’s cough, sneeze or heavy breathing. The common symptoms of coronavirus disease are dry cough, tiredness, breathlessness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache, and sore throat.
FAQs
Bamlanivimab+etesevimab works by inducing an antibody response in the body by instilling monoclonal antibodies that mimic the natural defences of the body and block the spike protein of the virus from attaching to body cells, thus arresting the progression of the disease.
Not enough literature exists to ascertain the effects of Bamlanivimab+etesevimab on fertility. Please consult your doctor in case of any concerns.
Remdesivir is an antiviral that functions to kill the virus. On the other hand, Bamlanivimab+etesevimab blocks the virus from attaching to the cells of the body. Thereby preventing the progression of the disease.
Vaccines stimulate the body to make its own antibodies against infection. On the other hand, monoclonal antibodies deliver lab-made antibodies against the virus.