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Bromfenac+moxifloxacin

About

Bromfenac+moxifloxacin belongs to ophthalmic eye medications primarily used to treat bacterial eye infections and reduce eye inflammation after cataract surgery in adults. Conjunctivitis (pink eye) is a common bacterial eye infection associated with the conjunctiva's inflammation or infection (white part of the eye) and the inner eyelid. Eye inflammation after cataract surgery is a common condition in which eyes become swollen and red.  

Bromfenac+moxifloxacin is a combination of two drugs: Bromfenac (analgesic) and Moxifloxacin (antibiotic). Bromfenac belongs to the class of non-steroidal anti-inflammatory drugs (pain relievers) that works by blocking cyclo-oxygenase (COX) enzyme in the body production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, helps in relieving pain and swelling after cataract surgery. Moxifloxacin belongs to the class of antibiotics that inhibits a bacterial enzyme called DNA gyrase required to survive a bacteria. Thereby, kills bacteria and prevents the spread of the infection in the eye.

Use Bromfenac+moxifloxacin as prescribed by your doctor. Bromfenac+moxifloxacin is only for use in the eyes. You are advised to use Bromfenac+moxifloxacin for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience mild eye irritation, eye pain, discomfort in the eye, seeing floaters or flashes of light before the eyes, or increased sensitivity of eyes to light. Most of these side effects of Bromfenac+moxifloxacin do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Bromfenac+moxifloxacin or any other medicines, please tell your doctor. Bromfenac+moxifloxacin is not recommended for children as the safety and effectiveness were not established. Avoid taking Bromfenac+moxifloxacin and consult a doctor if you are pregnant, especially in the last 3 months of pregnancy as it may harm the unborn baby. Drive only if your vision is clear as Bromfenac+moxifloxacin may cause temporary blurred vision immediately after applying.

Uses of Bromfenac+moxifloxacin

Bacterial eye infections, Eye inflammation after cataract surgery

Medicinal Benefits

Bromfenac+moxifloxacin is a combination of two drugs: Bromfenac and Moxifloxacin used to treat bacterial eye infections and reduce eye inflammation after cataract surgery in adults. Bromfenac belongs to the class of non-steroidal anti-inflammatory drugs (pain relievers) that block cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, helps in relieving pain and swelling after cataract surgery. Moxifloxacin is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative, gram-positive bacteria. It inhibits DNA gyrase (bacterial enzyme) in repairing and replicating the DNA (genetic material) of bacteria. Thereby, kills bacteria and clears the infection. 

Directions for Use

Bromfenac+moxifloxacin is for external use only. Wash your hands thoroughly with water before and after use. Use the dropper provided with the pack to instil the drops into the affected eye. Your doctor will advise you how many drops to instil based on your medical condition. Replace the outer cap after use. Do not touch the container’s tip to the eye, eyelids, or surrounding areas as it may contaminate Bromfenac+moxifloxacin.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bromfenac+moxifloxacin

  • Mild eye irritation
  • Eye pain
  • Discomfort in the eye
  • Seeing floaters or flashes of light before the eyes
  • Increased sensitivity of eyes to light

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Bromfenac+moxifloxacin or any other medicines, please tell your doctor. Bromfenac+moxifloxacin is not recommended for children as the safety and effectiveness were not established. Avoid taking Bromfenac+moxifloxacin and consult a doctor if you are pregnant, especially in the last 3 months of pregnancy as it may harm an unborn baby. Drive only if your vision is clear as Bromfenac+moxifloxacin may cause temporary blurred vision immediately after applying. If you have diabetes, rheumatoid arthritis, bleeding problems, dry eyes, cornea problems, before taking Bromfenac+moxifloxacin. You are advised to remove soft contact lenses before using Bromfenac+moxifloxacin as it may cause discoloration of soft contact lens. You are recommended to maintain a time gap of at least 5 minutes between using Bromfenac+moxifloxacin and other eye drops. Please do not touch the container's tip to the eye, eyelids, or surrounding areas as it may contaminate Bromfenac+moxifloxacin and cause eye infections. 

Drug Interactions

Drug-Drug Interaction: Bromfenac+moxifloxacin may interact with topical steroids (cortisone, loteprednol), blood thinners (warfarin, clopidogrel, aspirin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have diabetes, rheumatoid arthritis, bleeding problems, dry eyes, cornea problems, before taking Bromfenac+moxifloxacin.

Drug-Drug Interactions Checker List:

  • CORTISONE
  • LOTEPREDNOL
  • WARFARIN
  • CLOPIDOGREL
  • ASPIRIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of alcohol with Bromfenac+moxifloxacin is unknown. Please consult a doctor before consuming alcohol with Bromfenac+moxifloxacin.

    • Safety Warning

      Pregnancy

      caution

      Bromfenac+moxifloxacin is not recommended for use during pregnancy in the last 3 months as it may cause harm to the unborn baby. Bromfenac+moxifloxacin is prescribed only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Bromfenac+moxifloxacin is excreted in human milk. Bromfenac+moxifloxacin is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      Bromfenac+moxifloxacin may cause temporary blurred vision immediately after applying. Therefore, wait until your vision is clear before driving or operating machinery.

    • Safety Warning

      Liver

      safe if prescribed

      If you have any concerns regarding the use of Bromfenac+moxifloxacin in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      safe if prescribed

      If you have any concerns regarding the use of Bromfenac+moxifloxacin in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      unsafe

      Bromfenac+moxifloxacin is not recommended for children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Sleep for a minimum of 6 to 8 hours to rejuvenate your eyes naturally.
    • Wash your eyes with clean water at least two to three times a day. Do not wash your eyes if you have undergone any eye surgery for at least 2 weeks.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Eat foods rich in Omega-3 fatty acids such as sardines, mackerel, tuna, salmon, trout, and omega-3 fatty acid supplements.
    • Cut down your coffee intake as it may increase pressure in the eye and replace coffee with green tea.
    • Maintain a diet rich in antioxidants such as dark-green leafy vegetables, whole grains, citrus fruits, broccoli, Brussels sprouts, etc.
    • Avoid consumption of processed foods such as high-fat meats, sugary foods, dairy products, fast foods as they may increase inflammation.

    Special Advise

    • Avoid wearing contact lenses while using Bromfenac+moxifloxacin as it may cause discoloration of soft contact lenses.
    • If the infection persists or worsens after 5 days of using Bromfenac+moxifloxacin, please consult an eye specialist.

    Patients Concern

    Disease/Condition Glossary

    Cataract surgery is done to remove the eye's natural lens that has become cloudy and replace it with an artificial lens to restore clear eyesight. Eye inflammation may occur in some patients after cataract surgery due to disruption of the blood-aqueous barrier, which causes the release of specific inflammatory mediators such as leukotrienes and prostaglandins. The pain, swelling, and redness of the eye are normal after cataract surgery and are treated using topical corticosteroids or non-steroidal anti-inflammatory drugs. 

    Bacterial eye infections: The common bacterial eye infections are conjunctivitis, stye, or keratitis. Conjunctivitis (pink eye) is the infection or inflammation of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that spread by secretions of the eye. Symptoms include redness, itchy, and discharge or crusting around the eye. A stye, a bump on the eyelid, is also a common eye condition. Keratitis, inflammation of the cornea occurs due to frequent contact lenses, injury, diabetes, or surgery. 

    FAQs

    Bromfenac+moxifloxacin contains Bromfenac and Moxifloxacin. Bromfenac is a non-steroidal anti-inflammatory drug (pain reliever) that works by blocking the action of cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, helps in relieving pain and swelling after cataract surgery. Moxifloxacin is an antibiotic that works by inhibiting DNA gyrase (bacterial enzyme) involved in repairing and replicating the DNA (genetic material) of bacteria. Thereby, kills bacteria and clears the infection.

    You are not recommended to wear contact lenses while using Bromfenac+moxifloxacin as it contains benzalkonium chloride, a preservative that changes the color of the contact lens as it may be absorbed by soft contact lens. Benzalkonium chloride also causes irritation in the eye especially if you have disorders of the cornea (transparent layer at the front of the eye) or dry eyes. Therefore, you are advised to remove contact lenses before applying Bromfenac+moxifloxacin and reinsert after 15 minutes of using Bromfenac+moxifloxacin. Also, inform your doctor if you experience pain, stinging, or abnormal sensation in the eye after using Bromfenac+moxifloxacin.

    Bromfenac+moxifloxacin may cause temporary blurred vision immediately after applying. Therefore, you are recommended to wait until your vision is clear before driving or operating machinery.

    You are recommended to maintain a time gap of a minimum of 5 minutes between using Bromfenac+moxifloxacin and other eye drops. However, please consult a doctor before using other medicines with Bromfenac+moxifloxacin.

    You are not recommended to stop using Bromfenac+moxifloxacin without consulting your doctor as it may rarely flare-up inflammatory response such as retina swelling or worsen the infection. Therefore, use Bromfenac+moxifloxacin for as long as your doctor has prescribed it, and if you experience any difficulty while taking Bromfenac+moxifloxacin, please consult your doctor.

    Available Medicines for

    Bromfenac+moxifloxacin

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