Bromhexine+dextromethorphan+phenylpropanolamine
About
Bromhexine+dextromethorphan+phenylpropanolamine belongs to the class of medications called ‘Expectorant and Cough products’ used in the treatment of dry cough associated with cold/flu, allergies, and throat irritants. A cough is a reflex action that helps to clear any foreign irritant or mucus in the throat. Dry cough refers to a cough with no mucus (sputum) or secretions. A dry cough is mostly treated with cough suppressants and throat lozenges.
Bromhexine+dextromethorphan+phenylpropanolamine contains Bromhexine, Dextromethorphan, and Phenylpropanolamine. Bromhexine is an expectorant/mucolytic agent which thins mucus (phlegm) making it cough out easily. Dextromethorphan is a cough suppressant and acts by blocking the action of the cough centre in the brain that is responsible for the cough reflex. Phenylpropanolamine is a decongestant that narrows the small blood vessels providing relief from congestion or stuffiness in the nose.
You should take this medicine exactly as prescribed by the doctor. The common side-effects of Bromhexine+dextromethorphan+phenylpropanolamine are dizziness, headache, confusion, slow or shallow breathing, restlessness, nausea, vomiting, tremors, diarrhoea, stomach pain, skin rash, itching, palpitations (pounding heartbeat), and insomnia (difficulty to sleep). These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
It is not recommended to take Bromhexine+dextromethorphan+phenylpropanolamine if you are allergic to any contents of it. Do not use Bromhexine+dextromethorphan+phenylpropanolamine if you have taken monoamine oxidase (MAO) inhibitors, a type of antidepressant in the past 14 days. Before taking Bromhexine+dextromethorphan+phenylpropanolamine, inform your doctor if you have liver or kidney disease, high blood pressure, heart disease, thyroid problems, glaucoma (increased pressure in the eye), and an enlarged prostate gland or difficulty urinating. It is not recommended for use in children below 4 years of age. It should be used with caution in pregnant women, breastfeeding mothers, and elderly people. Alcohol may increase the risk of side-effects. Bromhexine+dextromethorphan+phenylpropanolamine may cause dizziness, so do not drive, or operate heavy machinery if you are not fully alert.
Uses of Bromhexine+dextromethorphan+phenylpropanolamine
Medicinal Benefits
Bromhexine+dextromethorphan+phenylpropanolamine is used in the treatment of dry cough which is associated with cold/flu, allergies, or throat irritants. It can suppress severe cough and helps to relieve congestion. It can also provide relief from a sore throat which is often accompanied by a dry cough. Take this medicine exactly as prescribed by the doctor for the best results.
Directions for Use
Storage
Side Effects of Bromhexine+dextromethorphan+phenylpropanolamine
- Dizziness
- Headache
- Confusion
- Slow or shallow breathing
- Restlessness
- Nausea
- Vomiting
- Tremors
- Diarrhoea
- Stomach pain
- Skin rash
- Itching
- Palpitations (pounding heartbeat)
- Insomnia (difficulty to sleep)
In-Depth Precautions and Warning
Drug Warnings
It is advised not to take Bromhexine+dextromethorphan+phenylpropanolamine if you have taken antidepressants (especially monoamine oxidase (MAO) inhibitors) in the past 14 days as it may cause life-threatening side-effects. Bromhexine+dextromethorphan+phenylpropanolamine should be used with caution in children with a history of allergies. Bromhexine+dextromethorphan+phenylpropanolamine should be used with caution in patients with peptic ulcer disease (stomach ulcers) as it may disrupt the mucous barrier in the stomach. It should also be used with caution in patients with asthma, severe liver, or kidney disease. Do not use any other cough or cold medicines while using Bromhexine+dextromethorphan+phenylpropanolamine.
Drug Interactions
Drug-Drug Interactions: Bromhexine+dextromethorphan+phenylpropanolamine may interact with antidepressants (isocarboxazid, tranylcypromine, selegiline, rasagiline, and methylene blue, etc.), antibiotics, non-steroidal anti-inflammatory drugs (celecoxib and indomethacin), anticancer agents (imatinib), a medicine used to treat heart rhythm problems (quinidine), a medicine used to treat chest pain (ranolazine), a medicine used to treat HIV (ritonavir), a medicine used to treat obesity (sibutramine), antifungal medicine (terbinafine), medicines used to treat high blood pressure (guanethidine and methyldopa), antibacterial agent (furazolidone), a medicine used to treat respiratory problems (theophylline), antipsychotic drugs (chlorpromazine, thioridazine, and prochlorperazine),
Drug-Food Interactions: Bromhexine+dextromethorphan+phenylpropanolamine may interact with caffeine present in cola, coffee, chocolate, and other products containing caffeine.
Drug-Disease Interactions: Bromhexine+dextromethorphan+phenylpropanolamine should be used with caution in patients with liver or kidney disease, high blood pressure, heart disease, asthma, stomach ulcers, thyroid problems, glaucoma (increased pressure in the eye), and an enlarged prostate gland or difficulty urinating.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol consumption may increase the risk of side-effects and worsen the condition.
Pregnancy
cautionIt is not known whether Bromhexine+dextromethorphan+phenylpropanolamine can affect the unborn baby. So, it should be used with caution in pregnant women.
Breast Feeding
cautionIt is not known whether Bromhexine+dextromethorphan+phenylpropanolamine can affect the nursing baby. So, please consult a doctor before taking this medicine.
Driving
cautionBromhexine+dextromethorphan+phenylpropanolamine may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.
Liver
cautionBromhexine+dextromethorphan+phenylpropanolamine should be used with caution in patients with liver disease. The dose may have to be adjusted by the doctor as required.
Kidney
cautionBromhexine+dextromethorphan+phenylpropanolamine should be used with caution in patients with kidney disease. The dose may have to be adjusted by the doctor as required.
Children
cautionBromhexine+dextromethorphan+phenylpropanolamine is not recommended for use in children below 4 years of age. In children above 4 years of age, the dose may have to be adjusted by the doctor based on age and body weight.
Habit Forming
Diet & Lifestyle Advise
- Avoid smoking as it may worsen your cough. Avoid second-hand or passive smoking too.
- Drink plenty of water to decrease throat irritation.
- Use a humidifier to moisten the air.
- Gargle with salt-water and have honey as they may help to suppress the cough.
- Avoid caffeinated and cold drinks as these may worsen the cough.
Patients Concern
Disease/Condition Glossary
Dry Cough: Cough is a reflex action that helps to clear any foreign irritant or irritants in the throat. Cough is of two types: dry cough and wet cough. In dry cough, no sputum is expelled and there is a sore throat, whereas, in wet cough, you cough-up sputum. Dry cough can be acute (short-term) or chronic (long-term). The most common causes of acute dry cough are cold/flu, allergic rhinitis (hay fever), and smoking. Acute dry cough can be treated with cough suppressants and throat lozenges. Chronic dry cough usually occurs due to asthma, gastroesophageal reflux, smoking, and lung cancer.
FAQs
Bromhexine+dextromethorphan+phenylpropanolamine contains Bromhexine, Dextromethorphan, and Phenylpropanolamine. Bromhexine is an expectorant/mucolytic agent which thins mucus (phlegm) making it cough out easily. Dextromethorphan is a cough suppressant and acts by blocking the action of the cough centre in the brain that is responsible for the cough reflex. Phenylpropanolamine is a decongestant that narrows the small blood vessels providing relief from congestion or stuffiness in the nose.
Bromhexine+dextromethorphan+phenylpropanolamine is used to treat dry cough associated with cold/flu, allergies, and throat irritants. It is not known whether it is safe to use in patients with asthma. So, please consult a doctor.
The common side-effects of Bromhexine+dextromethorphan+phenylpropanolamine are dizziness, headache, confusion, slow or shallow breathing, restlessness, nausea, vomiting, tremors, diarrhoea, stomach pain, skin rash, itching, palpitations (pounding heartbeat), and insomnia (difficulty to sleep). These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
It is not recommended to use Bromhexine+dextromethorphan+phenylpropanolamine while taking antidepressants or has taken antidepressants in the last 14 days. Concurrent use of both medicines may cause fatal side-effects such as anxiety, confusion, fever, tremors, increase or decrease in pulse rate, muscle rigidity, and fits.
Bromhexine+dextromethorphan+phenylpropanolamine may disrupt the mucous barrier in the stomach and worsen the peptic ulcer disease (stomach ulcers). So, it should be used with caution in patients with stomach ulcers.
