Cabazitaxel
About
Cabazitaxel belongs to a group of medicines known as microtubule inhibitors. It is used to treat advanced prostate cancer or metastatic prostate cancer that has already been treated with other medications. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.
Cabazitaxel contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Cabazitaxel should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.
Cabazitaxel is only for use in men. Men using this Cabazitaxel must use effective birth control whenever they have sex during your treatment and four months after their final dose. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding. Cabazitaxel injection may result in a substantial or life-threatening decrease in the number of white blood cells (a kind of blood cell needed to fight infection) in your blood. This increases your chances of developing a serious infection. Inform your doctor if you are 65 or older if you have or have ever had a low number of white blood cells associated with a fever if you have had radiation therapy, or if you are unable to eat a nutritious diet. Before and during treatment, your doctor will conduct laboratory tests to determine the quantity of white blood cells in your blood. If you have a low white blood cell count, your doctor may reduce your dose or stop or postpone your therapy. If your white blood cell count drops, your doctor may prescribe a prescription to help prevent life-threatening problems.
Uses of Cabazitaxel
Medicinal Benefits
Cabazitaxel contains Cabazitaxel, which belongs to a group of medicines known as microtubule inhibitors. Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Directions for Use
Side Effects of Cabazitaxel
- Nausea)
- Vomiting
- Neutropenia (lower-than-normal levels of neutrophils)
- Anemia (lower-than-normal amount of red blood cells)
- Leukopenia (low white blood cell count)
- Thrombocytopenia (low platelet level)
- Diarrhea
- Fatigue
- Nausea
- Vomiting
- Constipation
- Asthenia (abnormal weakness)
- Abdominal pain
- Hematuria (blood in urine)
- Back pain
- loss of appetite
- Peripheral neuropathy
- Fever
- Shortness of breath
- Altered taste
- Cough
- Joint pains
- Hair loss
In-Depth Precautions and Warning
Drug Warnings
Before taking the Cabazitaxel, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. White blood cells protect the body from infection. This medication may cause a decrease in the amount of white blood cells in your blood (neutropenia). You are more prone to catching an infection if your white blood cell count is low. When the quantity of white blood cells is too low, an infection can be deadly. It is critical to treat any infection as quickly as possible. Make an immediate call to the hospital. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant. Cabazitaxel injection can produce severe or life-threatening allergic reactions, especially during the first two infusions. Your doctor will give you drugs to prevent an allergic response at least 30 minutes before the Cabazitaxel injection. You should receive your infusion in a medical institution where you may be treated swiftly if you develop an allergic reaction.
Drug Interactions
Drug-Drug Interactions: Cabazitaxel interacts with medicines used to treat a wide variety of inflammatory conditions (e.g. adalimumab), immunomodulatory medication (e.g. baricitinib, fingolimod), Vaccinations (BCG Vaccine, Dengue vaccine, Smallpox vaccine), and psychiatric medication (e.g. clozapine),
Drug-Food Interactions: Do not drink Alcoholic beverages while treated with Cabazitaxel. It can affect the way the medicine works.
Drug-Disease Interactions: Inform your doctor before taking the Cabazitaxel if you suffer from Infections (bacterial/fungal/protozoal/viral), severe renal or hepatic dysfunctions, bone marrow depression/low blood counts, fever, and anaemia as it requires close monitoring.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption while on treatment with Cabazitaxel.
Pregnancy
unsafe-
Breast Feeding
unsafe-
Driving
cautionCabazitaxel may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.
Liver
cautionThe safety of Cabazitaxel has not been evaluated in patients with liver impairment. Inform your doctor before receiving the Cabazitaxel if you have had a Liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionKidney failure may occur with Cabazitaxel because of severe infection, loss of too much body fluid (dehydration), and other factors, and may result in death. Your doctor will examine you for this condition and, if necessary, treat you.
Children
unsafeThe safety and effectiveness of Cabazitaxel in pediatric patients have not been established.
Habit Forming
Diet & Lifestyle Advise
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Performing yoga may also help in improving both physical and mental health.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast, fried, processed meats, refined carbs and added sugars.
Special Advise
- Cabazitaxel should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Cabazitaxel.
- Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to the Cabazitaxel injection.
- Do not donate sperm during treatment with Cabazitaxel for four months after your last dose.
Patients Concern
Disease/Condition Glossary
Prostate cancer: Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen. Inability to urinate easily, pain, numbness, or sexual issues are among the symptoms. For men, it is the most typical type of cancer. Although the exact cause of prostate cancer is unknown, it may be brought on by family history, chemical exposure, or both. Prostate cancer risk factors include a family history of the disease, advanced age, obesity, and genetic changes.
FAQs
Cabazitaxel contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Based on the medical condition, Cabazitaxel may be given alone or with other medicines used to treat Prostate cancer.
Cabazitaxel is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.
You may not be able to get your partner pregnant after treatment with this drug. If you plan to have a baby, consult your doctor before beginning treatment. You might be able to store sperm before starting treatment.
Cabazitaxel, a prostate cancer medication, is used to treat prostate cancer.
No, it is unsafe to father a child while taking Cabazitaxel. It is recommended for sexually active men to use condoms while on treatment and for at least four months after their last dose of Cabazitaxel.
Cabazitaxel can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.
