Calcitriol+calcium Citrate+vitamin D3
About
Calcitriol+calcium Citrate+vitamin D3 belongs to the group of vitamins and is a Vitamin D metabolite. Calcitriol+calcium Citrate+vitamin D3 is used to strengthen bones and promote bone growth and development by enhancing the content of calcium and vitamin d, essential for bone integrity. Rickets and osteomalacia are bone diseases that happen due to nutritional deficiencies and are characterised by weakened bones and bone deformities. Osteoporosis is a disease that renders bones weak and brittle, prone to easy falls and fractures.
Calcitriol+calcium Citrate+vitamin D3 contains ‘’Calcitriol, Calcium Citrate and Vitamin D3.’’ Calcium is a vital component of bones. Calcitriol+calcium Citrate+vitamin D3 mobilises calcium ion uptake from the intestines, thus increasing calcium stores in the body. Thus, Calcitriol+calcium Citrate+vitamin D3 enhances bones' calcium and mineral content and finds application in preventing and treating diseases that render the bones weak or deformed.
Calcitriol+calcium Citrate+vitamin D3 is available over the counter. It may be taken as a tablet at the same time every day. Calcitriol+calcium Citrate+vitamin D3 may be taken with or without food. It should be swallowed as a whole with some water. Do not chew or crush Calcitriol+calcium Citrate+vitamin D3. Calcitriol+calcium Citrate+vitamin D3 does not generally cause any side effects. In very rare cases, Calcitriol+calcium Citrate+vitamin D3 may cause side effects such as mild loss of appetite, and feeling sick and tired. Most of these adverse effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to Calcitriol+calcium Citrate+vitamin D3 or any of its components. Keep your doctor informed if you have kidney problems, diabetes, phenylketonuria, hypercalcaemia, or have been immobilised for some time. Keep your doctor informed if you have recently had any surgery. Offer a detailed medical history and inform your doctor, especially if you are on steroids, heart medication, epilepsy medications, antibiotics, urine-producing medicines or antacids. Consult your doctor if you are pregnant, planning to get pregnant or if you are breastfeeding before taking Calcitriol+calcium Citrate+vitamin D3. Avoid consuming alcohol while on treatment with Calcitriol+calcium Citrate+vitamin D3.
Uses of Calcitriol+calcium Citrate+vitamin D3
Medicinal Benefits
Calcitriol+calcium Citrate+vitamin D3 is a Vitamin used to treat low calcium levels in the body. It contains Calcitriol, Calcium Citrate and Vitamin D3. It is used primarily in the treatment of bone disease and works by enhancing bones' calcium and mineral content. In addition, Calcitriol+calcium Citrate+vitamin D3 promotes the normal functioning of nerve cells. Calcitriol is an active form of Vitamin D3, which increases the production of carrier proteins responsible for mobilising calcium ions from the gut into the body, replenishing its stores. Calcitriol also activates bone-producing cells (osteoblasts) and reduces urinary loss of calcium from the body. Calcium citrate helps by restoring normal calcium levels in the body, required for the optimal functioning of bones. Hence, Calcitriol+calcium Citrate+vitamin D3 is useful in bone diseases such as rickets, osteomalacia, osteoporosis, renal osteodystrophy (bone deformities seen in patients undergoing dialysis for kidney disease) and endocrine conditions such as hypoparathyroidism, where inadequate parathormone production leads to a decrease in blood calcium.
Directions for Use
Storage
Side Effects of Calcitriol+calcium Citrate+vitamin D3
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Loss of appetite
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Weight Loss
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Fatigue
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Feeling sick
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Constipation
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Mood changes
In-Depth Precautions and Warning
Drug Warnings
Avoid taking Calcitriol+calcium Citrate+vitamin D3 if allergic to it. If you are allergic to sorbitol, inform the physician as Calcitriol+calcium Citrate+vitamin D3 contains sorbitol. Avoid dairy products such as milk and cheese with Calcitriol+calcium Citrate+vitamin D3 as they also contain Vitamin D, and there may be an interaction. Calcitriol+calcium Citrate+vitamin D3 should be used with caution in case of high risk or previous history of kidney disease or hypercalcaemia (high blood calcium levels). Keep your physician informed if you suffer from any kidney problems, hypercalcaemia, diabetes, phenylketonuria or have been immobilised for some time. Keep your physician informed if you have recently had any surgery. Offer a detailed medical history and inform the physician, especially if you are on steroids, heart medication such as digoxin, epilepsy medications that deplete calcium reserves, tetracycline antibiotics, urine-producing medicines (diuretics) or antacids. Consult your physician before using Calcitriol+calcium Citrate+vitamin D3 during pregnancy, breastfeeding, or even if you are trying to get pregnant.
Drug Interactions
Drug-Drug Interactions: Calcitriol+calcium Citrate+vitamin D3 may interact with Vitamin D analogues, antiepileptics (phenytoin, carbamazepine), diuretics (bendroflumethiazide, chlortalidone and indapamide), heart medicines (digoxin or digitoxin), magnesium-containing antacids, steroids (hydrocortisone, prednisolone, dexamethasone), cholesterol-reducing drugs (Cholestyramine), phosphate, tetracycline antibiotics (doxycycline, minocycline), and bisphosphonates (alendronate).
Drug-Food Interactions: Calcitriol+calcium Citrate+vitamin D3 may interact with sorbitol.
Drug-Disease Interactions: Calcitriol+calcium Citrate+vitamin D3 should be used with caution in patients with a known hypersensitivity disorder, diabetes mellitus, epilepsy, kidney disease, liver disease, kidney disease, phenylketonuria and hypercalcaemia.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionCaution is advised while taking alcohol with Calcitriol+calcium Citrate+vitamin D3. Please consult your physician if you have any concerns.
Pregnancy
cautionNot enough studies exist to ascertain the effect of Calcitriol+calcium Citrate+vitamin D3 on pregnancy. Calcitriol+calcium Citrate+vitamin D3 is known to be relatively safe in pregnancy. Please consult your physician if you have any concerns.
Breast Feeding
cautionCalcitriol+calcium Citrate+vitamin D3 is safe if advised during breastfeeding. However, your physician may suggest blood tests for you and your child to keep a check.
Driving
not applicableCalcitriol+calcium Citrate+vitamin D3 does not generally affect your ability to drive.
Liver
cautionExercise caution before using Calcitriol+calcium Citrate+vitamin D3 in case of pre-existing or a history of liver disease. Please consult your physician to address any concerns.
Kidney
cautionExercise caution before using Calcitriol+calcium Citrate+vitamin D3 in case of pre-existing or a history of kidney disease. Please consult your physician to address any concerns.
Children
consult your doctorCalcitriol+calcium Citrate+vitamin D3 is safe for use in children but should be used with caution and only in recommended paediatric doses in children below 12 years of age. Please consult your physician if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Keep your physician informed if you are planning to or are pregnant.
- Go easy on foods that are high in vitamin D, such as dairy products like milk and cheese. However, load up on oily fish and egg yolks.
- Avoid taking Calcitriol+calcium Citrate+vitamin D3 with Vitamin D supplements as there may be an interaction.
- Stay hydrated by drinking plenty of water.
- Doing weight-bearing exercises such as brisk walking, jogging, tennis, or even dance can promote overall bone health. However, do not over-exert yourself if you feel too tired or suffer from severely brittle bones.
- Muscle training activities such as yoga and Pilates can also be very helpful.
- Spend time under the sun (however, with proper sunscreen) for quality intake of Vitamin D.
- Limit alcohol and caffeine consumption and stop smoking, as these may have a negative effect on bone health. Smokers tend to have lower bone density than non-smokers.
Special Advise
- Take Calcitriol+calcium Citrate+vitamin D3 exactly as recommended. In case you miss a dose of Calcitriol+calcium Citrate+vitamin D3, skip it and resume when it is time for the second dose only. Do not ever take a double dose. It is very difficult to overdose on Calcitriol+calcium Citrate+vitamin D3 however, if you accidentally take extra doses of Calcitriol+calcium Citrate+vitamin D3, please inform your physician or go to a hospital immediately.
- Some of the common symptoms of an overdose can be nausea, constipation, feeling sick, dizziness, mood changes, loss of appetite and headache. Do not discontinue taking Calcitriol+calcium Citrate+vitamin D3 abruptly or without the advice of the physician.
- Please know that your physician may order blood tests to check your tolerance and need of Calcitriol+calcium Citrate+vitamin D3.
- In case you are breastfeeding, your doctor may order tests for your child as well, just to be on the safe side.
Patients Concern
Disease/Condition Glossary
Osteomalacia
Osteomalacia is a nutritional disorder seen in adults. It is characterised by soft and weak bones, making the body prone to falls and fractures. Osteomalacia is a disease in which the bones tend to break down faster than they can reform. It is caused by severe Vitamin D deficiency.
Rickets
Rickets is a nutritional disorder seen in children. It is also caused by a severe Vitamin D deficiency. Common signs and symptoms include deformities such as weakness in the bones ad spine and bone deformities such as bow legs and knock knees. In some cases, a deformity of the skull and flaccid muscles may also be seen.
Osteoporosis
Osteoporosis is a state in which the bones become weak and brittle. It is often brought about by disease and age (menopausal osteoporosis). In osteoporosis, bone-destroying cells' activity surpasses bone-forming cells' activity. Most people do not suffer from any symptoms until there’s a fracture and bones literally start to break.
Hypoparathyroidism
Hypoparathyroidism is a condition in which the body produces inadequate levels of parathormone (PTH), which regulates the stores of calcium and phosphate in the body, thereby disrupting bone growth and development. It also causes muscle cramps, twitching facial muscles, dry skin, mood changes and tingling in the extremities.
FAQs
Calcitriol+calcium Citrate+vitamin D3 works by enhancing calcium levels in the body by increasing the absorption of calcium from gut cells.
Please see an orthopaedic doctor if you have had a fracture. Calcitriol+calcium Citrate+vitamin D3 is used in the treatment of bone disease and has limited use in the treatment of fractures as a fracture is more of surgical concern.
If you suffer from CKD, please consult with your doctor before using Calcitriol+calcium Citrate+vitamin D3.
Calcitriol+calcium Citrate+vitamin D3 is known to play a role in the treatment of various types of bone disease. However, the treatment duration and efficacy rate depend on your condition and its requirements. Usually, it takes about 2 weeks for Calcitriol+calcium Citrate+vitamin D3 to show its benefits.
