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Calcitriol+clobetasol Propionate

About

Calcitriol+clobetasol Propionate belongs to the class of medicines called 'antipsoriatic agents', primarily used to treat psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. These red patches can commonly appear on the scalp, elbows, knees, and lower back.

Calcitriol+clobetasol Propionate comprises of two medicines, namely Clobetasol propionate (corticosteroid) and Calcitriol (Vitamin D3). Clobetasol propionate blocks the production of prostaglandins (chemical messengers), which make the skin red, swollen and itchy. Calcitriol is a man-made form of Vitamin D that inhibits the excess production of skin cells which leads to the formation of scales and patches of the skin in psoriasis. Together, Calcitriol+clobetasol Propionate helps treat psoriasis.

Calcitriol+clobetasol Propionate is for external use only. Your doctor will advise the dose and duration based on your medical condition. Common side-effects of Calcitriol+clobetasol Propionate are burning/stinging sensation, itching, redness, dryness and irritation at the site of application. These side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Avoid contact of Calcitriol+clobetasol Propionate with your eyes, nose or mouth. Rinse it off with water thoroughly if contact occurs. Do not use Calcitriol+clobetasol Propionate to treat acne, rosacea (facial flushing on and around the nose), and perioral dermatitis (red or scaly rashes around the mouth). Pregnant and breastfeeding women should use Calcitriol+clobetasol Propionate only with proper consultation and caution. Calcitriol+clobetasol Propionate is not recommended for children less than 12 years of age.

Uses of Calcitriol+clobetasol Propionate

Psoriasis.

Medicinal Benefits

Calcitriol+clobetasol Propionate treats psoriasis and is a combination of two medicines: namely: Clobetasol propionate and Calcitriol. Clobetasol propionate is a corticosteroid medicine. It blocks the production of prostaglandins (chemical messengers), which make the skin red, swollen and itchy. Calcitriol is a man-made form of Vitamin D that is an antipsoriatic agent. It inhibits the excess production of skin cells that leads to the formation of scales and patches of the skin in psoriasis. Calcitriol+clobetasol Propionate helps treat plaque psoriasis, a most common type of psoriasis that develops thick red patches on the skin, with a silver or white scaly layer.

Directions for Use

Calcitriol+clobetasol Propionate is for external use only. Apply a small amount as a thin layer on the affected area with clean hands. Avoid contact with the nose, mouth or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Calcitriol+clobetasol Propionate

  • Burning or stinging sensation
  • Itching
  • Dryness
  • Irritation
  • Redness at the application site

In-Depth Precautions and Warning

Drug Warnings

Avoid using Calcitriol+clobetasol Propionate if you are allergic to any of its components. Let your doctor know if you have a history of liver or kidney diseases before starting Calcitriol+clobetasol Propionate. Calcitriol+clobetasol Propionate is not recommended for diaper rash. If you are pregnant or breastfeeding, you should use Calcitriol+clobetasol Propionate only with proper doctor consultation and caution. Calcitriol+clobetasol Propionate is for external use only. Avoid contact of Calcitriol+clobetasol Propionate with eyes, nose and mouth. Rinse it off with water thoroughly if contact occurs. Do not put a bandage or a dressing on the affected area while using Calcitriol+clobetasol Propionate unless advised by the doctor. Always wash hands before and after the application of Calcitriol+clobetasol Propionate unless the area of treatment is hands.

Drug Interactions

Drug-Drug Interaction: Calcitriol+clobetasol Propionate may interact with corticosteroids (prednisone) and immunosuppressants (cyclosporine).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Before using Calcitriol+clobetasol Propionate, let your doctor know if you have any fungal, viral, protozoa infections, liver or kidney diseases, diabetes, and hypervitaminosis D (excess Vitamin D levels in the blood).

Drug-Drug Interactions Checker List:

  • PREDNISONE
  • CYCLOSPORINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not known if Calcitriol+clobetasol Propionate interacts with Calcitriol+clobetasol Propionate. Please consult your doctor.

    • Safety Warning

      Pregnancy

      caution

      There is limited data on how the Calcitriol+clobetasol Propionate affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Calcitriol+clobetasol Propionate.

    • Safety Warning

      Breast Feeding

      caution

      It is not known if Calcitriol+clobetasol Propionate passes into the breast milk. Please consult your doctor before using Calcitriol+clobetasol Propionate if you are breastfeeding. If you need to apply the cream or ointment on your breasts, don't do this shortly before giving a feed.

    • Safety Warning

      Driving

      safe if prescribed

      There have been no studies to investigate the effect of Calcitriol+clobetasol Propionate on driving performance or the ability to operate machinery.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before using Calcitriol+clobetasol Propionate. Your doctor will weigh the benefits and potential risks before prescribing Calcitriol+clobetasol Propionate.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases before using Calcitriol+clobetasol Propionate. Your doctor will weigh the benefits and potential risks before prescribing Calcitriol+clobetasol Propionate.

    • Safety Warning

      Children

      unsafe

      Calcitriol+clobetasol Propionate is not recommended for children less than 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Use mild soap while taking baths and prefer warm baths.
    • Always wear loose-fitting clothes to avoid further sweat and the spread of infections.
    • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
    • Do not walk barefoot at places like gym showers to prevent infections.
    • Do not scratch the affected area of the skin, as it can spread the infection to other body parts.
    • Avoid sharing towels, combs, bed sheets, shoes or socks with others.
    • Wash your bed sheets and towels regularly.
    • Avoid or limit the intake of alcohol and caffeine.
    • Do not scratch or pick your skin to avoid getting the affected area infected.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and sleep peacefully. 

    Special Advise

    If you do not notice any improvement of your infection after using Calcitriol+clobetasol Propionate for one to two weeks, please consult your doctor.

    Patients Concern

    Disease/Condition Glossary

    Psoriasis: It is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. These red patches can commonly appear on the scalp, elbows, knees, and lower back. Psoriasis is a noncontagious (not spread by contact) chronic immune condition with no cure. It can be mild, moderate, or severe based on the patches' coverage on the skin. People with 80-90% suffering from psoriasis have plaque psoriasis. Psoriasis can be pustular, guttate, inverse, and erythrodermic. Pustular psoriasis mainly covers the palms of the hands and soles of the feet. Guttate psoriasis usually starts in childhood or young age and affects the torso and limbs. Inverse psoriasis forms bright red lesions in the armpits, groin, and under the breasts. Erythrodermic psoriasis is triggered by sunburn, infections, and certain medications that cause redness and shedding of the skin.

    FAQs

    Calcitriol+clobetasol Propionate is composed of Clobetasol propionate, a steroid and Calcitriol, an antipsoriatic agent. These two medicines help in treating the red bumpy patches and relieves itchiness and redness at psoriasis affected areas.

    Calcitriol+clobetasol Propionate is for topical (for skin use) application only. Avoid Calcitriol+clobetasol Propionate contact with eyes, nose, and mouth. Do not put a bandage or a dressing on the affected area while using Calcitriol+clobetasol Propionate unless advised by the doctor.

    Calcitriol+clobetasol Propionate can make your skin more sensitive to the harmful effects of the sunlight. Hence it is advised to use sunscreen and wear protective clothing while using Calcitriol+clobetasol Propionate. It is also recommended to avoid tanning booths and sunlamps.

    Calcitriol+clobetasol Propionate consists of Clobetasol propionate, a corticosteroid that may affect blood sugar levels. It is advised to consult your doctor before using Calcitriol+clobetasol Propionate if you are diabetic. Monitor your blood sugar levels regularly.

    Calcitriol+clobetasol Propionate is indicated for the treatment of psoriasis. It is not recommended for diaper rash. Your baby's paediatrician will suggest other medicines for the treatment of diaper rash.

    Do not stop using Calcitriol+clobetasol Propionate even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the disease may not be cured completely.

    Available Medicines for

    Calcitriol+clobetasol Propionate

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