Calcium+calcitriol+menaquinone
About
Calcium+calcitriol+menaquinone belongs to the class of 'dietary supplements, primarily used to treat low blood calcium levels. Calcium+calcitriol+menaquinone effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Calcium+calcitriol+menaquinone can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium.
Calcium+calcitriol+menaquinone consists of three medicines, namely: Calcium (mineral), Calcitriol (Vitamin D3), and Menaquinone (Vitamin K2). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Menaquinone is also known as Vitamin K2. Vitamin K2 helps to maintain bone density by promoting calcium transport from the bloodstream into the bone. Calcium-regulating proteins also require menaquinone in the arteries.
Your doctor will decide the dosage based on your medical condition. In some cases, Calcium+calcitriol+menaquinone can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Calcium+calcitriol+menaquinone do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to Calcium+calcitriol+menaquinone or its inactive components, please inform your doctor. Please tell your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, and kidney stones before starting Calcium+calcitriol+menaquinone. Pregnant or breastfeeding women should consult their doctor before taking Calcium+calcitriol+menaquinone. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Calcium+calcitriol+menaquinone may pass into the breast milk; hence breastfeeding mothers need to seek medical advice before starting Calcium+calcitriol+menaquinone.
Uses of Calcium+calcitriol+menaquinone
Medicinal Benefits
Calcium+calcitriol+menaquinone is used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium+calcitriol+menaquinone consists of Calcium (mineral), Calcitriol (Vitamin D3), and Menaquinone (Vitamin K2). Calcium is a mineral and prevents or treats calcium deficiency. It helps to maintain bone and teeth health. Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. Menaquinone, also known as Vitamin K2, helps maintain bone density by promoting calcium transport from the bloodstream into the bone. Calcium-regulating proteins also require it in the arteries.
Directions for Use
Storage
Side Effects of Calcium+calcitriol+menaquinone
- Constipation or stomach upset
- Nausea
- Vomiting
- Loss of appetite
- Mood changes
- Weakness, tiredness
- Fast or pounding heartbeat
- Bone/muscle pain
- Headache
In-Depth Precautions and Warning
Drug Warnings
Let your doctor know if you are allergic to Calcium+calcitriol+menaquinone or its inactive components. Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. Chewable tablets of Calcium+calcitriol+menaquinone contain sugar or aspartame; hence caution should be taken to have diabetes and phenylketonuria (increased levels of an amino acid called phenylalanine). Calcitriol in higher doses may harm the foetus. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Calcium+calcitriol+menaquinone may pass into the breast milk, hence consult your doctor before taking Calcium+calcitriol+menaquinone if you are a breastfeeding mother.
Drug Interactions
Drug-Drug Interaction: Calcium+calcitriol+menaquinone may interact with central nervous system stimulants (dextroamphetamine), anti-depressants (duloxetine), minerals (ferrous sulfate), anti-ulcer drugs (ranitidine), synthetic thyroid hormone (levothyroxine), painkillers (aspirin), calcium supplements (ergocalciferol), anti-clotting drugs (warfarin), drugs treating high cholesterol levels (cholestyramine), and drugs that treat high blood phosphorus levels (sevelamer). Some medications like tetracycline antibiotics (doxycycline), quinolone antibiotics (ciprofloxacin), drugs treating bone loss (alendronate), weight-loss drugs (orlistat), and anti-cancer drugs (estramustine) may affect the calcium absorption into the body.
Drug-Food Interaction: Avoid or reduce the intake of caffeine, soft drinks and alcohol that inhibit calcium absorption.
Drug-Disease Interaction: Calcium+calcitriol+menaquinone is not recommended if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionDrinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Calcium+calcitriol+menaquinone.
Pregnancy
cautionDuring pregnancy, use higher doses of Calcium+calcitriol+menaquinone than the daily dietary allowance only when advised by the doctor. Your doctor will weigh the potential risks and benefits before recommending Calcium+calcitriol+menaquinone.
Breast Feeding
cautionConsult your doctor before taking Calcium+calcitriol+menaquinone if you are breastfeeding. Calcium+calcitriol+menaquinone can pass into the breast milk. If Calcium+calcitriol+menaquinone is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.
Driving
not applicableNo interaction found/established.
Liver
cautionLet your doctor know if you have any history of liver diseases before taking Calcium+calcitriol+menaquinone. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.
Kidney
cautionIt is advised to seek doctor advice before starting Calcium+calcitriol+menaquinone if you have kidney diseases like kidney stones or undergoing dialysis.
Children
consult your doctorThe doctor will decide the dosage of Calcium+calcitriol+menaquinone based on the child's age and weight.
Habit Forming
Diet & Lifestyle Advise
- Include dairy products like milk, yoghurt, cheese or milk-based custard in your diet.
- Eat daily a serving of broccoli, cabbage, bok choy, spinach and other green leafy vegetables.
- Snack on calcium-rich nuts like Brazil nuts or almonds.
- Sprinkle sesame seeds over your food, vegetables and salads. Sesame seeds are high in calcium.
- Avoid or reduce the intake of caffeine, soft drinks and alcohol that inhibit calcium absorption.
- Replace the meat with tofu or tempeh for extra calcium in your food.
Special Advise
- Low phosphate diet is recommended to control serum phosphorus levels in patients undergoing dialysis.
- Clinical monitoring of serum electrolyte concentrations and cardiac function is recommended.
Patients Concern
Disease/Condition Glossary
Osteoporosis: It is a bone disease that makes the bones weak and brittle by decreasing bone density. It is known as a silent disease since it is not revealed until a bone is broken easily or fractured. Symptoms include backache, easily breaking bones, and hunched or stooped posture. Thinning of bones can be prevented by treating with medications, calcium supplements, a calcium-rich diet, and lifestyle changes.
Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D.
Tetany: A disease condition due to low levels of calcium (hypocalcaemia) in the body that causes cramps and spasms in the hands, feet, and larynx (voice box.
Hypoparathyroidism: It is a disease characterized by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany.
FAQs
Calcium+calcitriol+menaquinone is a dietary supplement that treats low levels of calcium in the blood. It consists of Calcium, Calcitriol, and Menaquinone. Calcium is a mineral and prevents or treats calcium deficiency. Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the decreased activity of the parathyroid glands). Menaquinone (Vitamin K2) maintains bone density by promoting calcium transport from the bloodstream into the bone.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Milk is considered to be the best source of calcium. You can take Calcium+calcitriol+menaquinone with milk.
Calcium+calcitriol+menaquinone can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Calcium+calcitriol+menaquinone as a daily supplement if you have any kidney problems or a history of kidney stones.
Calcium+calcitriol+menaquinone is used to increase low levels of calcium in the body. Hence it is not advised to use Calcium+calcitriol+menaquinone during hypercalcemia, since it causes the overdose of calcium leading to kidney stones and other effects.
Calcitriol in Calcium+calcitriol+menaquinone can increase inorganic phosphate levels in serum; hence it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low phosphate diet to control serum phosphorus levels in patients undergoing dialysis.
