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Cefixime+cloxacillin

About

Cefixime+cloxacillin belongs to a group of medications called ‘Antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Cefixime+cloxacillin contains Cefixime and Cloxacillin. Cefixime is a cephalosporin antibiotic, whereas Cloxacillin is a penicillin antibiotic. Cefixime+cloxacillin has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis.

You should take this medicine exactly as prescribed by the doctor. Cefixime+cloxacillin may cause side effects such as indigestion, stomach pain, nausea, vomiting, vaginal itching or discharge, diarrhoea and belching. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Cefixime+cloxacillin if you are allergic to penicillin, any other antibiotics, or this medicine's contents. Cefixime+cloxacillin should be used with caution in patients with liver or kidney impairment, colitis (inflammation of the large intestine), and a weak immune system. Cefixime+cloxacillin should be used with caution in pregnant women, breastfeeding mothers and elderly people. Consult your doctor before using Cefixime+cloxacillin in children. Cefixime+cloxacillin may not interact with alcohol and may not affect your ability to drive.

Uses of Cefixime+cloxacillin

Bacterial infections

Medicinal Benefits

Cefixime+cloxacillin is used to treat bacterial infections. It is active against both gram-positive and gram-negative bacteria. It has a broad spectrum of activity and can be used to treat bacterial infections such as tonsillitis (swollen tonsils), pharyngitis (sore throat), pneumonia (inflammation of the air sacs present in the lungs), bronchitis (inflammation of the bronchi) and other respiratory tract infections, skin and soft tissue infections and urinary tract infections.

Directions for Use

Take Cefixime+cloxacillin as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cefixime+cloxacillin

  • Indigestion
  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Belching
  • Vaginal itching or discharge

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor immediately if you notice severe stomach pain and watery or bloody stools while using Cefixime+cloxacillin . If Cefixime+cloxacillin is prescribed for prolonged periods, blood tests should be performed to monitor liver, kidney function, and blood count. Cefixime+cloxacillin may cause superinfections (an additional infection that occurs with different microbes) such as candidiasis (fungal infection), especially in patients with weak immune systems (due to steroid or immune suppressant therapy).

Drug Interactions

Drug-Drug Interactions: Cefixime+cloxacillin may interact with a pain killer (aspirin) and medicine used to treat gout (probenecid).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: People with renal failure, severe liver diseases, seizures (fits), colitis (bowel disease that affects the large intestine, causing irritation, inflammation and ulcers in the colon) and weak immune systems should not take Cefixime+cloxacillin.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • PROBENECID
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Cefixime+cloxacillin may interact with alcohol.

    • Safety Warning

      Pregnancy

      caution

      Cefixime+cloxacillin should be used in pregnant women only if the doctor thinks the clinically needed when benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Cefixime+cloxacillin should be used with caution in breastfeeding mothers only if the doctor thinks the clinically needed when benefits outweigh the risks.

    • Safety Warning

      Driving

      safe if prescribed

      Cefixime+cloxacillin may not affect your ability to drive.

    • Safety Warning

      Liver

      caution

      Cefixime+cloxacillin should be used with caution in patients with liver diseases as it may affect liver function. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Cefixime+cloxacillin should be used with caution in patients with kidney diseases as it may cause nephrotoxicity (damage to the kidney). The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      caution

      Please consult your doctor before using this medicine in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Probiotics should be taken after taking the full course of Cefixime+cloxacillin to restore some of the healthy bacteria in the intestines that may have been killed taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
    • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
    • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Cefixime+cloxacillin.
    • Avoid intake of alcoholic beverages with Cefixime+cloxacillin as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Cefixime+cloxacillin in fighting off infections.

    Special Advise

    Cefixime+cloxacillin may affect some laboratory test results, so let your doctor know that you are taking this medicine before undergoing any laboratory tests.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any organ of the body and multiply very quickly. Many give off chemicals called toxins, which can damage tissue and make you sick. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue.  Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.

    FAQs

    Cefixime+cloxacillin is a combination of antibiotics. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis.

    Cefixime+cloxacillin may be effective for sinus infection. However, it is not recommended to take any medicine without consulting your doctor to avoid unwanted effects.

    People allergic to penicillin should not take Cefixime+cloxacillin as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Cefixime+cloxacillin contains cloxacillin, which has a similar structure to that of penicillin.

    The common side-effects of Cefixime+cloxacillin are indigestion, stomach pain, nausea, vomiting, vaginal itching or discharge, diarrhoea and belching. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

    Cefixime+cloxacillin may affect liver and kidney function and blood count, so inform your doctor that you are taking Cefixime+cloxacillin before undergoing any blood tests.

    Available Medicines for

    Cefixime+cloxacillin

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