CEFIXIME+ORNIDAZOLE
About
CEFIXIME+ORNIDAZOLE belongs to the group of 'antibacterial medications,' primarily used to treat bacterial infections. A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. They can target any part of the body and multiply very quickly. These infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis.
CEFIXIME+ORNIDAZOLE contains an antibiotic combination, Cefixime and Ornidazole, primarily used to treat bacterial infections. Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis, arresting cell wall assembly resulting in bacterial cell death. Ornidazole kills other infectious microorganisms in addition to bacteria by damaging their DNA, does preventing the bacteria to reproduce or repair by themselves.
In some cases, you may experience certain common side-effects such as nausea, vomiting, loss of appetite, dizziness, tremors, headache, diarrhoea, stomach pain, flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Before starting CEFIXIME+ORNIDAZOLE, please inform your doctor if you have any allergy (against these antibiotics), kidney or liver problems. Do not take CEFIXIME+ORNIDAZOLE on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking CEFIXIME+ORNIDAZOLE if you are pregnant or breastfeeding. Avoid alcohol consumption while taking CEFIXIME+ORNIDAZOLE as it may cause increased dizziness. CEFIXIME+ORNIDAZOLE may cause dizziness and vision problems, so be cautious while driving. CEFIXIME+ORNIDAZOLE is not recommended for use in children.
Uses of CEFIXIME+ORNIDAZOLE
Medicinal Benefits
CEFIXIME+ORNIDAZOLE is an antibiotic combination containing Cefixime, and Ornidazole primarily used to treat bacterial infections. Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis, arresting cell wall assembly resulting in bacterial cell death. Ornidazole kills other infectious microorganisms in addition to bacteria by damaging their DNA, does preventing the bacteria to reproduce or repair by themselves.
Directions for Use
Storage
Side Effects of CEFIXIME+ORNIDAZOLE
- Headache
- Nausea
- Dizziness
- Diarrhoea
- Loss of appetite
- Indigestion
- Flatulence
- Stomach pain
In-Depth Precautions and Warning
Drug Warnings
Do not take CEFIXIME+ORNIDAZOLE if you are allergic to CEFIXIME+ORNIDAZOLE or any of its ingredients. Tell your doctor if you have liver problems (jaundice), muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), diabetes, electrolyte imbalance (low potassium or magnesium level), and kidney or liver diseases. In rare cases, the use of CEFIXIME+ORNIDAZOLE can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking CEFIXIME+ORNIDAZOLE and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you. Maintain a minimum gap of two hours between CEFIXIME+ORNIDAZOLE and antacid, vitamin, and mineral medicines. Consult your doctor before taking CEFIXIME+ORNIDAZOLE if you are pregnant or breastfeeding. Avoid alcohol consumption while taking CEFIXIME+ORNIDAZOLE as it causes increased dizziness. CEFIXIME+ORNIDAZOLE may cause dizziness and vision problems, so be cautious while driving. CEFIXIME+ORNIDAZOLE is not recommended for use in children unless recommended by a doctor. Also, it is recommended to complete the course of medicine even if you feel better as CEFIXIME+ORNIDAZOLE contains antibiotics, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Drug Interactions
Drug-Drug Interactions: CEFIXIME+ORNIDAZOLE may have interaction with pain killers (aspirin, ibuprofen), antibiotic (azithromycin, ciprofloxacin, sulfamethoxazole, trimethoprim, metronidazole, erythromycin), anti-diabetic (metformin), diuretics (furosemide), antihistamine medicines (chlorpheniramine), blood thinners (warfarin)
Drug-Food Interactions: Eating grapefruit during antibiotics treatment can prevent the body from utilising CEFIXIME+ORNIDAZOLE properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. Avoid taking too much of calcium-enriched foods and drinks as it might affect the working of CEFIXIME+ORNIDAZOLE. Aluminium and magnesium-containing antacids, Multivitamins, multi-minerals containing zinc and iron should not be consumed along with CEFIXIME+ORNIDAZOLE; maintain a minimum gap of two hours between both.
Drug-Disease Interactions: CEFIXIME+ORNIDAZOLE may interact in patients with diabetes mellitus, renal dysfunction, liver disease, seizure disorders, colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon), muscle problem (muscle weakness).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is best to avoid alcohol while taking CEFIXIME+ORNIDAZOLE.
Pregnancy
cautionCEFIXIME+ORNIDAZOLE should not be used during pregnancy unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast Feeding
cautionCEFIXIME+ORNIDAZOLE is not recommended to be used during breastfeeding. CEFIXIME+ORNIDAZOLE has not been found to pass through mother's milk to the baby, yet nursing mothers should avoid breastfeeding while taking CEFIXIME+ORNIDAZOLE as a precaution.
Driving
cautionPlease drive with caution; CEFIXIME+ORNIDAZOLE usually causes drowsiness and confusion; it affects driving ability.
Liver
cautionCEFIXIME+ORNIDAZOLE to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionCEFIXIME+ORNIDAZOLE to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
cautionCEFIXIME+ORNIDAZOLE to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.
Habit Forming
Diet & Lifestyle Advise
- Probiotics should be taken after taking the full course of CEFIXIME+ORNIDAZOLE to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
- Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
- Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of CEFIXIME+ORNIDAZOLE.
- Avoid intake of alcoholic beverages with CEFIXIME+ORNIDAZOLE as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the CEFIXIME+ORNIDAZOLE in fighting off infections.
Special Advise
- CEFIXIME+ORNIDAZOLE contains ornidazole, which may affect coagulation test or prothrombin time (time is taken for blood clotting), liver function tests, and serum tests. Regularly monitor these tests if you are taking CEFIXIME+ORNIDAZOLE.
- Cefixime in CEFIXIME+ORNIDAZOLE may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunization/vaccinations while using this medication unless your doctor tells you to.
Patients Concern
Disease/Condition Glossary
Bacterial infection: It is a condition in which harmful bacteria enter, multiply, and infect the body. They can target any part of the body and multiply very quickly. These infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. When you get infected with these germs, you can experience generalized symptoms, like fevers, chills and fatigue. Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.
FAQs
CEFIXIME+ORNIDAZOLE contains Cefixime and Ornidazole. Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis, arresting cell wall assembly resulting in bacterial cell death. Ornidazole kills other infectious microorganisms in addition to bacteria by damaging their DNA, does preventing the bacteria to reproduce or repair by themselves.
CEFIXIME+ORNIDAZOLE can cause diarrhoea, which may be a sign of a new infection. If you have diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.
CEFIXIME+ORNIDAZOLE contains ornidazole, which should be avoided with magnesium and aluminium-containing antacids along with CEFIXIME+ORNIDAZOLE. Maintain a minimum gap of two hours between both for better results and to avoid drug-drug interaction.
CEFIXIME+ORNIDAZOLE contains Ornidazole, which is not recommended in patients with the sexually transmitted disease (STD). Taking CEFIXIME+ORNIDAZOLE may worsen the patient's symptoms, thus shouldn't be taken unless recommended/consulted by a doctor.
Consult your doctor before taking CEFIXIME+ORNIDAZOLE if you have diabetes as CEFIXIME+ORNIDAZOLE may cause hypoglycemia (low blood sugar levels) or hyperglycemia (high blood sugar levels). Regularly monitor blood sugar levels while taking CEFIXIME+ORNIDAZOLE to avoid unpleasant events.
Yes, CEFIXIME+ORNIDAZOLE is an antibiotic used in the treatment of urinary tract infections (UTIs). CEFIXIME+ORNIDAZOLE is also used in other bacterial infection such as infections of lungs, sinus, skin, respiratory tract infections, urinary tract infections, bone and joint infections.
