Cefoperazone
About
Cefoperazone belongs to the group of medicines called broad-spectrum cephalosporin antibiotics used for the treatment, control, prevention, & improvement of the symptoms of conditions like respiratory tract infections and bacterial infections.
Cefoperazone contains Cefoperazone. It binds to specific PBPs (penicillin-binding proteins) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis, which is necessary for their survival. Thus it kills bacteria and helps treat bacterial infections.
Cefoperazone will be administered by a healthcare professional; do not self-administer. Sometimes, Cefoperazone may cause injection site reactions, diarrhoea, nausea, vomiting, headaches and rash. Most of these side effects of Cefoperazone do not require medical attention and gradually resolve over time. However, contact your doctor if the side effects persist or bother you.
Before receiving Cefoperazone, please inform your doctor if you are allergic to any antibiotic or food products. Inform your doctor before taking Cefoperazone if you are pregnant, planning for pregnancy, or breastfeeding. Let your doctor know about your medical history and ongoing medications to rule out any interactions. Avoid alcohol consumption while taking Cefoperazone to prevent unpleasant side effects.
Uses of Cefoperazone
Medicinal Benefits
Cefoperazone contains Cefoperazone. Cefoperazone is a broad-spectrum cephalosporin that has been proposed to be useful against Pseudomonas infections. It is a third-generation antibiotic drug used to treat bacterial infections produced by susceptible organisms in the body, such as respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. It works by inhibiting the third and last stage of bacterial cell wall synthesis, which is necessary for their survival. Thus, it kills bacteria and helps treat bacterial infections.
Directions for Use
Storage
Side Effects of Cefoperazone
- Injection site reactions
- Diarrhoea
- Nausea
- Vomiting
- Headaches
- Rash
- Convulsions or fits
- Decrease in kidney function
- Increase in liver enzymes
- Inflammation of a vein
- Low white blood cell count
In-Depth Precautions and Warning
Drug Warnings
Avoid taking Cefoperazone if you are allergic to any of its components. Notify your doctor immediately if you experience any allergic reactions after taking Cefoperazone. Inform your doctor about all the medicines you take and your health conditions, especially colitis (inflammation in the colon's lining) and hypoprothrombinaemia (decreased prothrombin production), to rule out any unpleasant side effects. Antibiotic resistance develops when bacteria gain the ability to resist the treatment that was designed to kill them. This can be avoided by complying with the dose and duration of therapy as suggested by your doctor. Even if your symptoms improve after a few doses of Cefoperazone, complete the entire course of medication.
Drug Interactions
Drug-Drug Interactions: Cefoperazone may interact with vaccines (BCG vaccine, Cholera vaccine live, Typhoid vaccine live) and certain types of antibiotics (e.g. rifampin or rifampicin).
Drug-Food Interactions: Avoid the consumption of alcohol or alcoholic beverages.
Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the colon's lining), hypoprothrombinaemia (decreased prothrombin production), alcoholism, dialysis, and kidney or liver dysfunction.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionConsuming alcohol along with Cefoperazone is not advisable as it may cause unintended effects.
Pregnancy
cautionCefoperazone should be used in pregnancy if clearly needed. If you are pregnant, inform your doctor before receiving this injection.
Breast Feeding
safe if prescribed&name considered safe if used in breastfeeding. There has been no significant research on the use of Cefoperazone in breastfeeding/nursing moms. However, if you are breastfeeding, inform your doctor before receiving Cefoperazone.
Driving
not applicableCefoperazone does not affect your driving abilities.
Liver
cautionIf you have liver problems, inform your doctor before receiving Cefoperazone. Your doctor may adjust the dose if necessary or prescribe a suitable alternative based on your condition.
Kidney
cautionIf you have kidney problems, inform your doctor before receiving Cefoperazone. Your doctor may adjust the dose if necessary or prescribe a suitable alternative based on your condition.
Children
consult your doctorLimited information regarding the use of Cefoperazone in children is available, so please consult a doctor for more information.
Habit Forming
Diet & Lifestyle Advise
- It would be best to take probiotics after taking the full course of Cefoperazone to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
- Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
- Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Cefoperazone.
- Avoid intake of alcoholic beverages with Cefoperazone as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Cefoperazone in fighting off infections.
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce toxins, damaging tissue and making you sick. It can target any body part and multiply very quickly. When infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.
FAQs
Cefoperazone contains Cefoperazone. It works by inhibiting the third and last stage of bacterial cell wall synthesis, which is necessary for their survival. Thus, it kills bacteria and treats bacterial infections.
After taking an antibiotic, you may need to wait up to three hours before eating or drinking dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also affect the working of antibiotics.
Inform your doctor if your symptoms are not relieved even after finishing the full course of treatment. If the symptoms worsen while using this medicine, seek immediate medical help.
Usually, Cefoperazone starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better. Please consult your doctor for more information.
