Ceftriaxone+tazobactam
About
Ceftriaxone+tazobactam belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, blood, bones and joints, heart, brain, chest, ears, skin, or soft tissues. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Ceftriaxone+tazobactam does not work against infections caused by the virus.
Ceftriaxone+tazobactam is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor). Ceftriaxone belongs to the class of antibiotics that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
You are advised to take Ceftriaxone+tazobactam for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, rash, or abnormalities with white blood cells and platelets. Most of these side effects of Ceftriaxone+tazobactam do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Ceftriaxone+tazobactam, penicillins, or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Ceftriaxone+tazobactam. Drive only if you are alert as Ceftriaxone+tazobactam may cause dizziness. You are recommended to complete the full course of Ceftriaxone+tazobactam as prescribed by your doctor for effective results. Ceftriaxone+tazobactam may interact with certain tests such as glucose (sugar) in urine and coomb’s test, giving unusual results. Therefore, inform the doctor that you are taking Ceftriaxone+tazobactam before undergoing any tests.
Uses of Ceftriaxone+tazobactam
Medicinal Benefits
Ceftriaxone+tazobactam is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor) used to treat several bacterial infections. Ceftriaxone is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
Directions for Use
Storage
Side Effects of Ceftriaxone+tazobactam
- Diarrhoea
- Rash
- Raised white blood cells
- Raised platelets
- Nausea
- Vomiting
- Upset stomach
- Blood clots
- Dizziness
- headache
- a lump where the medicine was injected,
- Sweating
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Ceftriaxone+tazobactam, penicillins, or any other medicines, please tell your doctor. If you have kidney or liver problems, diarrhea, hemolytic anemia (reduction in red blood cells that may make your skin pale yellow and cause breathlessness or weakness), kidney or gall stones, or inflammation of the large intestine, inform your doctor before taking Ceftriaxone+tazobactam. If you are pregnant or breastfeeding, please inform your doctor before taking Ceftriaxone+tazobactam. Drive only if you are alert as Ceftriaxone+tazobactam may cause dizziness. You are recommended to complete the full course of Ceftriaxone+tazobactam as prescribed by your doctor for effective results. Ceftriaxone+tazobactam may interact with certain tests such as glucose (sugar) in urine and coomb’s test, giving unusual results. Therefore, inform the doctor that you are taking Ceftriaxone+tazobactam before undergoing any tests. If you are on a low-sodium diet or are about to receive calcium-containing products, please inform your doctor before taking Ceftriaxone+tazobactam.
Drug Interactions
Drug-Drug Interaction: Ceftriaxone+tazobactam may interact with a blood thinner (heparin), drugs used to lower high uric acid levels (probenecid), neuromuscular blocking agent (vecuronium), anticancer drug (methotrexate), water tablet (furosemide) and antibiotics (chloramphenicol, gentamicin, streptomycin).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have kidney or liver problems, diarrhea, hemolytic anemia (reduction in red blood cells that may cause breathlessness or weakness and make your skin pale yellow), kidney or gall stones, inflammation of the large intestine, inform your doctor before taking Ceftriaxone+tazobactam.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionInteraction of Ceftriaxone+tazobactam with alcohol is unknown. Please consult a doctor before consuming alcohol while using Ceftriaxone+tazobactam.
Pregnancy
cautionPlease consult a doctor if you are pregnant or planning for pregnancy. Ceftriaxone+tazobactam is given to pregnant women only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionIt is unknown whether Ceftriaxone+tazobactam is excreted in human milk. Ceftriaxone+tazobactam is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.
Driving
cautionCeftriaxone+tazobactam may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Ceftriaxone+tazobactam.
Liver
cautionTake Ceftriaxone+tazobactam with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Ceftriaxone+tazobactam with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionCeftriaxone+tazobactam is not recommended for premature and new-born babies up to 28 days who has jaundice or certain blood problems. However, Ceftriaxone+tazobactam is given to children only if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Take probiotics after completing the full course of Ceftriaxone+tazobactam to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
- Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
- Make sure you drink plenty of water or other fluids every day while you are taking Ceftriaxone+tazobactam.
- Avoid alcohol consumption as it may increase adverse effects.
Special Advise
- Regular blood tests are recommended if you take Ceftriaxone+tazobactam for a long time to monitor changes in white blood cells, platelets, and liver functioning.
- If you are about to undergo any blood or urine tests, inform your doctor that you are taking Ceftriaxone+tazobactam as it may interfere with urine the est (for sugar) and Coomb’s test results.
Patients Concern
Disease/Condition Glossary
Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.
FAQs
Ceftriaxone+tazobactam contains Ceftriaxone and Tazobactum. Ceftriaxone is an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
Ceftriaxone+tazobactam may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Ceftriaxone+tazobactam.
You are not recommended to take Ceftriaxone+tazobactam with streptomycin as co-administration of these two medicines may increase the risk of kidney damage. However, please consult your doctor before taking Ceftriaxone+tazobactam with other medicines to adjust the dose appropriately.
Ceftriaxone+tazobactam may cause diarrhoea as a common side effect. However, if the condition persists, worsens or notices blood or mucus in stools, avoid taking Ceftriaxone+tazobactam and consult a doctor immediately.
Ceftriaxone+tazobactam is not used to treat viral infections. Ceftriaxone+tazobactam is an antibiotic which is used to treat only bacterial infections.
Ceftriaxone+tazobactam should be used with caution in patients with kidney problems as it may increase the risk of adverse effects. Therefore, inform your doctor if you have any kidney problems before taking Ceftriaxone+tazobactam so that the dose may be adjusted accordingly.
