Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate
About
Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate belongs to a class of medication called 'cough and cold medications' primarily used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.
Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic agent; it helps to loosen mucus, making it easier to cough out.
Take Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate as prescribed. Your doctor will recommend how often you take Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, vomiting, and headache. Everyone doesn't need to experience the above side effects. In some cases, Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate may cause a severe allergic skin reaction, probably due to paracetamol, which may disappear in some time.
Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate. If you have high blood pressure (hypertension), liver or kidney disease, coronary artery disease (heart disease), avoid using Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). Increase in the intake of fluids to keep throat hydrated.
Uses of Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate
Medicinal Benefits
Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate is primarily used to treat common cold symptoms. It is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic) and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic, it helps to loosen mucus, making it easier to cough out.
Directions for Use
Storage
Side Effects of Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate
- Drowsiness
- Sleepiness
- Nausea
- Fatigue
- Vomiting
- Headache
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate or any other medicines, please tell your doctor. Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate. If you have high blood pressure (hypertension), liver or kidney disease, coronary artery disease (heart disease), avoid using Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). Increase in the intake of fluids to keep throat hydrated.
Drug Interactions
Drug-Drug Interaction: Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate may interact with anti-allergic medications (diphenhydramine, cetirizine), antidepressant medications (duloxetine, imipramine, amitriptyline), anticonvulsants medications (clonazepam), antianxiety medication (alprazolam), cough suppressants (dextromethorphan), and bronchodilator (albuterol).
Drug-Food Interaction: Avoid intake of Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate with alcohol as they may cause increased drowsiness, dizziness, and difficulty concentrating.
Drug-Disease Interaction: If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, Raynaud's phenomenon (decreased blood flow to the fingers), enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate to avoid excessive drowsiness and sleepiness.
Pregnancy
cautionThe safety of Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionChlorpheniramine+paracetamol+phenylephrine+sodium Citrate is known to pass through milk in small amounts. Use in breastfeeding women is not recommended as it may cause unpleasant side effects to the baby like unusual irritability, excitement.
Driving
unsafeChlorpheniramine+paracetamol+phenylephrine+sodium Citrate is known to cause drowsiness, so please do not drive or operate any machinery which requires concentration.
Liver
cautionTake Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionChlorpheniramine+paracetamol+phenylephrine+sodium Citrate is not recommended for children below 2 years. However, it can be given to children more than 2 years of age only if the doctor has prescribed it.
Habit Forming
Diet & Lifestyle Advise
- Wash your hands with soap and water regularly to prevent the spread of germs.
- Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
- Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
- Gargle with salt water for relief from sore throat.
- Avoid alcohol consumption with Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate as it may cause tiredness, drowsiness, or lack of concentration.
Special Advise
- Avoid alcohol consumption with Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate as it may cause tiredness, drowsiness, or lack of concentration.
- Do not take Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, consult your doctor.
FAQs
Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic; it helps to loosen mucus, making it easier to cough out.
It is not recommended to take a higher than the recommended dose as it may lead to unpleasant side effects and toxicity. If you feel the severity of your symptoms is increasing, please consult your doctor.
Do not use Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate if you have used any MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing your skin or eyes). In rare cases, paracetamol present in Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness, or rash, immediately contact your doctor and stop taking Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate.
No, it would be best if you did not take Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate.
It is not advisable to breastfeed while taking Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate as it contains Chlorpheniramine (an antihistamine), which is known to pass through the breast milk and may harm the baby. So, please consult the doctor before breastfeeding if you are taking Chlorpheniramine+paracetamol+phenylephrine+sodium Citrate.
Sodium citrate is an additive and a mucolytic agent. It helps to loosen the mucus and hence makes it easier to cough out.
