Chlorpheniramine+paracetamol+phenylpropanolamine
About
Chlorpheniramine+paracetamol+phenylpropanolamine belongs to a class of medication called 'cough and cold medications' primarily used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person is sick, sneezes, coughs, or talks.
Chlorpheniramine+paracetamol+phenylpropanolamine is composed of three medicines, namely: Chlorpheniramine (anti-histamine), Phenylpropanolamine (decongestant) and Paracetamol (mild analgesic and antipyretic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylpropanolamine helps shrink the blood vessels in the nasal passage, reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.
Chlorpheniramine+paracetamol+phenylpropanolamine should be taken as advised by your doctor. The dose of this medicine will be based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, difficulty sleeping, and headache. Everyone doesn't need to experience the above side effects. In some cases, Chlorpheniramine+paracetamol+phenylpropanolamine may cause a severe allergic skin reaction, probably due to paracetamol, which may disappear in some time.
Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Chlorpheniramine+paracetamol+phenylpropanolamine. If you have high blood pressure (hypertension), liver or kidney disease, or coronary artery disease (heart disease), avoid using Chlorpheniramine+paracetamol+phenylpropanolamine as it may worsen your condition and symptom. Do not take Chlorpheniramine+paracetamol+phenylpropanolamine if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Intake of more than 4 gm of paracetamol can damage your liver, so it is better to avoid the use of Chlorpheniramine+paracetamol+phenylpropanolamine in severe liver damage. Phenylpropanolamine in Chlorpheniramine+paracetamol+phenylpropanolamine should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers).
Uses of Chlorpheniramine+paracetamol+phenylpropanolamine
Medicinal Benefits
Chlorpheniramine+paracetamol+phenylpropanolamine is primarily used to treat the common cold and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It is composed of four medicines, namely: Chlorpheniramine, Phenylpropanolamine, and Paracetamol. Chlorpheniramine belongs to the class of antihistamines or anti-allergic drugs; it helps to treat allergy symptoms like runny and stuffy nose and watery eyes. Phenylpropanolamine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that lowers body temperature and body pain caused due to cold.
Directions for Use
Storage
Side Effects of Chlorpheniramine+paracetamol+phenylpropanolamine
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Drowsiness
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Nervousness
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Headache
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Dizziness
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Insomnia (difficulty falling or staying asleep)
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Allergic reactions
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Chlorpheniramine+paracetamol+phenylpropanolamine or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Chlorpheniramine+paracetamol+phenylpropanolamine. Do not use Chlorpheniramine+paracetamol+phenylpropanolamine in breastfeeding mothers without a doctor’s advice. Chlorpheniramine+paracetamol+phenylpropanolamine is not recommended for children below 4 years. Please do not take more than the prescribed dose of Chlorpheniramine+paracetamol+phenylpropanolamine as it may cause liver damage and can be lethal. If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking Chlorpheniramine+paracetamol+phenylpropanolamine. Do not take Chlorpheniramine+paracetamol+phenylpropanolamine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days. Also, avoid intake of chocolate, alcohol, and caffeine-containing beverages like coffee as they may increase the risk of severity of side effects. Do not take Chlorpheniramine+paracetamol+phenylpropanolamine if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylpropanolamine in Chlorpheniramine+paracetamol+phenylpropanolamine should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers).
Drug Interactions
Drug-Drug Interaction: Chlorpheniramine+paracetamol+phenylpropanolamine may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, imipramine, amitriptyline), anticonvulsants (clonazepam), antianxiety drug (alprazolam), cough suppressants (dextromethorphan), bronchodilator (albuterol, theophylline), sleeping agent (ramelteon), pain killers (ibuprofen).
Drug-Food Interaction: Avoid intake of Chlorpheniramine+paracetamol+phenylpropanolamine with caffeine-containing foods (like coffee) and alcoholic beverages as they may cause increased drowsiness, dizziness, and difficulty concentrating.
Drug-Disease Interaction: If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, Raynaud's phenomenon (decreased blood flow to the fingers), enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking Chlorpheniramine+paracetamol+phenylpropanolamine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeDo not consume alcohol while on treatment with Chlorpheniramine+paracetamol+phenylpropanolamine as it may cause serious side effects.
Pregnancy
cautionThe safety of Chlorpheniramine+paracetamol+phenylpropanolamine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult your doctor.
Breast Feeding
cautionChlorpheniramine+paracetamol+phenylpropanolamine is known to pass through milk in small amounts. Use in breastfeeding is not recommended as it may cause unpleasant side effects to the baby, like unusual irritability and excitement in your infant.
Driving
unsafeChlorpheniramine+paracetamol+phenylpropanolamine is known to cause drowsiness, so please do not drive or operate machinery which requires concentration after taking Chlorpheniramine+paracetamol+phenylpropanolamine.
Liver
cautionTake Chlorpheniramine+paracetamol+phenylpropanolamine with caution, especially if you have a history of liver disease. Your doctor may adjust the dose if necessary based on your clinical condition.
Kidney
cautionTake Chlorpheniramine+paracetamol+phenylpropanolamine with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose if necessary based on your clinical condition.
Children
cautionChlorpheniramine+paracetamol+phenylpropanolamine is not recommended for use in children below 4 years. However, it can be given to children more than 4 years of age only if the doctor has prescribed it.
Habit Forming
Diet & Lifestyle Advise
- Wash your hands with soap and water regularly to prevent the spread of germs.
- Eat plenty of foods rich in good bacteria, like yogurt to improve overall health.
- Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
- Gargle with salt water for relief from sore throat.
- Avoid alcohol consumption with Chlorpheniramine+paracetamol+phenylpropanolamine as it may cause tiredness, drowsiness, or lack of concentration.
Special Advise
- Avoid alcohol consumption with Chlorpheniramine+paracetamol+phenylpropanolamine as it may cause tiredness, drowsiness, or lack of concentration.
- Do not take Chlorpheniramine+paracetamol+phenylpropanolamine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days.
- Please inform your doctor if you are pregnant or breastfeeding before starting Chlorpheniramine+paracetamol+phenylpropanolamine as it contains caffeine, which can pass in the breast milk, which may have a stimulating effect on a breastfed child.
Patients Concern
Disease/Condition Glossary
Common cold: The virus, commonly referred to as 'rhinoviruses,' which affects the nose and throat, causes the common cold (upper respiratory tract). Children under six years are most at risk for colds, but healthy adults can also be affected by getting 2 to 3 colds a year. Most people recover from cold symptoms in a week to ten days. Smokers and those who are exposed to allergens like pollen, dust, and other irritants may experience symptoms that last longer. Sneezing, runny or stuffy nose, sore throat, cough, congestion, mild body aches, low fever, mild headache, and unwell are all symptoms of the common cold. The nasal discharge may occasionally thicken and turn yellow or green, but this is not always a sign of a bacterial infection.
Allergies: These occur when foreign elements that cause allergy-causing agents (allergens) attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Chlorpheniramine+paracetamol+phenylpropanolamine is composed of three medicines, namely: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), and Paracetamol (mild analgesic and antipyretic). Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins', which are responsible for pain and fever.
Do not use Chlorpheniramine+paracetamol+phenylpropanolamine if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Chlorpheniramine+paracetamol+phenylpropanolamine if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Chlorpheniramine+paracetamol+phenylpropanolamine may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness, or rash, immediately contact your doctor and stop taking Chlorpheniramine+paracetamol+phenylpropanolamine.
Chlorpheniramine+paracetamol+phenylpropanolamine avoid taking medicines or food containing caffeine like cold drinks, coffee, chocolate, and tea. Also, avoid consumption of alcohol while taking Chlorpheniramine+paracetamol+phenylpropanolamine as it might increase drowsiness.
You are not recommended to stop taking Chlorpheniramine+paracetamol+phenylpropanolamine without consulting your doctor as it may worsen or cause a recurring cough. Therefore, take Chlorpheniramine+paracetamol+phenylpropanolamine for as long as your doctor has prescribed it, and if you experience any difficulty while taking Chlorpheniramine+paracetamol+phenylpropanolamine, please consult your doctor.
Do not breastfeed while using Chlorpheniramine+paracetamol+phenylpropanolamine as it contains an antihistamine drug Chlorpheniramine, and it contains caffeine, which can pass through the breast milk and may harm the baby.
