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CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN

About

CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN belongs to the class of medication called ‘cough and cold preparations’ primarily used to treat symptoms of common cold and allergies such as sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as ‘rhinoviruses’. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks.

CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN is a combination of five drugs, namely: Chlorpheniramine (antihistamine), Phenylephrine (decongestant), Bromhexine (mucolytic agent), Paracetamol (analgesic and antipyretic), and Guaifenesin (expectorant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases mucus production. Bromhexine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, helps to cough out easily. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus, and helps to remove it from the airways.

Take CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN as prescribed. Your doctor will recommend how often you take CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, restlessness, flushing (redness of the skin), loss of appetite, vomiting, insomnia (difficulty in falling or staying asleep), nausea, stomach upset, blurred vision, constipation, and dry mouth, nose or throat. Most of these side effects of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN. Do not use CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Avoid using CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN to loosen mucus and protect yourself from being dehydrated or overheated during exercise and in hot weather as CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN contains chlorpheniramine that decreases sweating and increases the risk of heatstroke. If you have high blood pressure, diabetes fits, glaucoma, hyperthyroidism (overactive thyroid), stomach ulcer, chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN.

Uses of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN

Common cold symptoms, Allergies

Medicinal Benefits

CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN is a combination of five drugs, namely: Chlorpheniramine, Phenylephrine, Bromhexine, Paracetamol, and Guaifenesin. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases mucus production. Bromhexine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, helps to cough out easily. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus, and helps to remove it from the airways.

Directions for Use

Take CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN

  • Drowsiness
  • Dizziness
  • Nausea
  • Vomiting
  • Nervousness or restlessness
  • Headache
  • Flushing (redness of the skin)
  • Loss of appetite
  • Stomach upset
  • Constipation
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Dry mouth, nose or throat

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN. Do not use CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN in breastfeeding mothers without doctor’s advice as it may be excreted in breast milk and cause harm to the baby. CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN is not recommended for children below 12 years of age. Please do not take more than the prescribed dose of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN as it may cause liver damage and cause serious adverse effects. Avoid using CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN to loosen mucus and protect yourself from being dehydrated or overheated during exercise and in hot weather as CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN contains chlorpheniramine that decreases sweating and increases the risk of heatstroke. If you have high blood pressure, diabetes fits, glaucoma, hyperthyroidism (overactive thyroid), stomach ulcer, chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN.

Drug Interactions

Drug-Drug Interaction: CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may interact with anti-allergic drugs (diphenhydramine, cetirizine), antacid (ranitidine), central nervous system stimulants (methylphenidate), antidepressants (duloxetine, sertraline), cough suppressants (dextromethorphan), narcotic analgesics (hydrocodone), antianxiety drug (alprazolam).

Drug-Food Interaction: Avoid foods rich in carbohydrates, and pectin including jellies, cabbage, brussels sprouts, and broccoli as CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may interact with these foods. Also, avoid intake of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Avoid consumption of alcohol with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN it may as it may increase the risk of liver damage and cause increased drowsiness, dizziness, and difficulty in concentrating.

Drug-Disease Interaction: If you have high blood pressure, diabetes, fits, glaucoma, hyperthyroidism (overactive thyroid), stomach ulcer, chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN.

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • RANITIDINE
  • METHYLPHENIDATE
  • DULOXETINE
  • SERTRALINE
  • DEXTROMETHORPHAN
  • HYDROCODONE
  • ALPRAZOLAM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN.

    • Safety Warning

      Pregnancy

      caution

      The safety of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

    • Safety Warning

      Breast Feeding

      caution

      CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may be excreted in breast milk and cause harm to the baby. Therefore, CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN should not be used in breastfeeding mothers without doctor’s advice.

    • Safety Warning

      Driving

      caution

      CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN.

    • Safety Warning

      Liver

      caution

      Take CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      unsafe

      CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may not be recommended for children below 12 years of age. However, please consult a doctor before giving CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN to children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Wash your hands with soap and water regularly to prevent the spread of germs.
    • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
    • Drink plenty of fluids to avoid dehydration.
    • Gargle with salt water for relief from sore throat.
    • Avoid consumption of alcohol with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN as it may cause tiredness, drowsiness or lack of concentration.

    Special Advise

    • Do not give CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN to children below 12 years of age.
    • If you have allergic skin reactions like skin redness or rash that spreads and causes blistering and peeling, immediately contact a doctor.
    • Intake of CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may cause dizziness and drowsiness so avoid driving, operating heavy machinery, and performing hazardous tasks. Besides this, do not drink alcohol with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN to avoid liver problems as CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN contains paracetamol. 
    • Let your doctor know if you have already been prescribed sleeping pills or psychotropic drugs. Please do not take any psychotropic medicines with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN as it may lead to dizziness and sedation. 

    Patients Concern

    Disease/Condition Glossary

    Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is an indication of bacterial infection.

    Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.

    FAQs

    CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN contains Chlorpheniramine, Phenylephrine, Bromhexine, Paracetamol and Guaifenesin. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases the mucus production. Bromhexine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in lungs, windpipe and nose. Thereby, helps to cough out easily. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from airways. Together CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN helps in relieving symptoms of common cold and allergic symptoms like sneezing, watery eyes, stuffy/runny nose, headache, fever and coughing.

    CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN contains Chlorpheniramine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

    No, you are not recommended to consume alcohol with CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN as it may increase the risk of liver damage and cause increased drowsiness, dizziness and lack of concentration.

    CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN is excreted in breast milk and may affect the health of the baby. Therefore, if you are breastfeeding, please inform your doctor before taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN so that the doctor may prescribe CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN if the benefits are greater than risks.

    Yes, CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN may cause drowsiness. It is not necessary for everyone taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN to experience this side effect. Therefore, avoid driving if you feel drowsy after taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN.

    It would be best if you avoid taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN with 'cetirizine' as co-administration of these two medicines may increase adverse effects such as drowsiness, dizziness and difficulty in concentrating. However, please consult a doctor before taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN with other medicines.

    No, you are not recommended to stop taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN for as long as your doctor has prescribed it, and if you experience any difficulty while taking CHLORPHENIRAMINE+PHENYLEPHRINE+BROMHEXINE+PARACETAMOL+GUAIFENESIN, please consult your doctor.

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