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Chlorthalidone+cilnidipine+telmisartan

About

Chlorthalidone+cilnidipine+telmisartan belongs to a group of medicines called antihypertensives used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults. Hypertension is a condition in which the force of blood against the artery walls is very high. It will be an addition to the workload of the heart and arteries.

Chlorthalidone+cilnidipine+telmisartan is a combination of three drugs, namely: Chlorthalidone (diuretic), Cilnidipine (calcium channel blocker), and Telmisartan (angiotensin II receptor blocker). Chlorthalidone belongs to the class of diuretics (water tablets) that works by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Cilnidipine is a calcium channel blocker that acts on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. Telmisartan works by blocking a hormone called angiotensin II in the body that causes the narrowing of blood vessels leading to high blood pressure. Thereby, Chlorthalidone+cilnidipine+telmisartan widens and relaxes blood vessels. Thus, it lowers high blood pressure.

Take Chlorthalidone+cilnidipine+telmisartan as prescribed by your doctor. You are advised to take Chlorthalidone+cilnidipine+telmisartan for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, low blood pressure, stomach upset, or tiredness. Most of these side effects of Chlorthalidone+cilnidipine+telmisartan do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Chlorthalidone+cilnidipine+telmisartan or any other medicines, please tell your doctor. Chlorthalidone+cilnidipine+telmisartan is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Chlorthalidone+cilnidipine+telmisartan and consult a doctor. If you are about to take anesthesia or undergo any surgery, you are advised to inform your doctor that you are taking Chlorthalidone+cilnidipine+telmisartan. Drive only if you are alert as Chlorthalidone+cilnidipine+telmisartan may cause dizziness or tiredness. You are recommended to avoid alcohol consumption with Chlorthalidone+cilnidipine+telmisartan as it may increase the risk of low blood pressure.

Uses of Chlorthalidone+cilnidipine+telmisartan

Hypertension (high blood pressure)

Medicinal Benefits

Chlorthalidone+cilnidipine+telmisartan contains Chlorthalidone, Cilnidipine, and Telmisartan used to treat high blood pressure. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Cilnidipine and Telmisartan relax and widen blood vessels. Thus, Chlorthalidone+cilnidipine+telmisartan lowers high blood pressure and reduces the risk of stroke, heart attack, or other heart problems.

Directions for Use

Take Chlorthalidone+cilnidipine+telmisartan with food to avoid stomach upset or take it as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Chlorthalidone+cilnidipine+telmisartan

  • Dizziness
  • Headache
  • Low blood pressure
  • Stomach upset
  • Tiredness
  • Tachycardia
  • Ankle Swelling
  • Flushing
  • Loss of appetite
  • Change in blood glucose levels
  • Gastric Irritation

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Chlorthalidone+cilnidipine+telmisartan or any other medicines, please tell your doctor. Chlorthalidone+cilnidipine+telmisartan is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Chlorthalidone+cilnidipine+telmisartan and consult a doctor. If you are about to take anesthesia or undergo any surgery, you are advised to inform your doctor that you are taking Chlorthalidone+cilnidipine+telmisartan. Avoid taking Chlorthalidone+cilnidipine+telmisartan if you have low levels of sodium or potassium in the blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, or severe liver or kidney problems. Drive only if you are alert as Chlorthalidone+cilnidipine+telmisartan may cause dizziness or tiredness. You are recommended to avoid alcohol consumption with Chlorthalidone+cilnidipine+telmisartan as it may increase the risk of low blood pressure.

Drug Interactions

Drug-Drug Interaction: Chlorthalidone+cilnidipine+telmisartan may interact with non-steroidal anti-inflammatory drugs (aspirin, ibuprofen), calcium channel blockers (amlodipine), water pills (amiloride, spironolactone), heart-related medicines (quinidine, digoxin), antimanic drug (lithium), antibiotics (erythromycin, rifampicin), anticonvulsant (phenytoin).

Drug-Food Interaction: Avoid taking potassium-rich foods such as bananas, sweet potatoes, nuts, and noni juice with Chlorthalidone+cilnidipine+telmisartan as it may result in hyperkalemia (high levels of potassium in the blood) and cause severe adverse effects. Also, Chlorthalidone+cilnidipine+telmisartan may interact with grapefruit juice and increase the levels of Chlorthalidone+cilnidipine+telmisartan in blood.

Drug-Disease Interaction: Avoid taking Chlorthalidone+cilnidipine+telmisartan if you have low levels of sodium or potassium in the blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. If you have diabetes, high cholesterol, low blood pressure, renal artery stenosis (narrowing of blood vessels to one or both the kidneys), heart, liver, or kidney problems, inform your doctor before taking Chlorthalidone+cilnidipine+telmisartan.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • IBUPROFEN
  • AMLODIPINE
  • AMILORIDE
  • SPIRONOLACTONE
  • QUINIDINE
  • DIGOXIN
  • LITHIUM
  • ERYTHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Chlorthalidone+cilnidipine+telmisartan as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

    • Safety Warning

      Pregnancy

      unsafe

      Chlorthalidone+cilnidipine+telmisartan is not recommended for pregnant women as it may cause serious harm to the unborn baby. Please consult a doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      unsafe

      Chlorthalidone+cilnidipine+telmisartan may be excreted in human milk and harm the baby. Therefore, avoid taking Chlorthalidone+cilnidipine+telmisartan if you are breastfeeding and consult a doctor.

    • Safety Warning

      Driving

      caution

      Chlorthalidone+cilnidipine+telmisartan may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Chlorthalidone+cilnidipine+telmisartan.

    • Safety Warning

      Liver

      caution

      Take Chlorthalidone+cilnidipine+telmisartan with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Chlorthalidone+cilnidipine+telmisartan if you have severe liver disease.

    • Safety Warning

      Kidney

      caution

      Take Chlorthalidone+cilnidipine+telmisartan with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Chlorthalidone+cilnidipine+telmisartan if you have severe kidney disease.

    • Safety Warning

      Children

      unsafe

      Chlorthalidone+cilnidipine+telmisartan is not recommended for children below 18 years as safety and effectiveness is not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
    • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
    • Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, reacting in certain situations, and doing activities that you enjoy by making time for yourself.
    • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.
    • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
    • Quit smoking and avoid the consumption of alcohol.

    Special Advise

    • Monitor your blood pressure regularly, and if you notice any fluctuations, please consult a doctor.
    • Your doctor may order regular monitoring of blood glucose and electrolyte levels.

    Patients Concern

    Disease/Condition Glossary

    Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.

    FAQs

    Chlorthalidone+cilnidipine+telmisartan contains Chlorthalidone, Cilnidipine and Telmisartan. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Cilnidipine and Telmisartan relaxes and widens blood vessels. Thus, Chlorthalidone+cilnidipine+telmisartan lowers high blood pressure and reduces the risk of stroke, heart attack, or other heart problems.

    You are not recommended to take ibuprofen with Chlorthalidone+cilnidipine+telmisartan as it may reduce the effect of Chlorthalidone+cilnidipine+telmisartan and increase the risk of impaired kidney function. However, if you experience loss of appetite, sudden weight loss or weight gain, weakness, muscle cramps, vomiting, nausea, decreased or increased urination, irregular heart rhythm, and fluid retention, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

    Chlorthalidone+cilnidipine+telmisartan may increase potassium levels in the blood. Therefore, it is recommended to avoid intake of potassium supplements and foods that are rich in potassium such as bananas, sweet potatoes, nuts, and noni juice with Chlorthalidone+cilnidipine+telmisartan as it may result in hyperkalaemia (high levels of potassium in the blood) and cause severe adverse effects such as irregular heartbeat, muscle paralysis, and kidney failure.

    Chlorthalidone+cilnidipine+telmisartan may cause dizziness in some patients. Therefore, if you feel dizzy after taking Chlorthalidone+cilnidipine+telmisartan, avoid driving or operating heavy machinery.

    You are not recommended to stop taking Chlorthalidone+cilnidipine+telmisartan without consulting your doctor even if you find symptomatic relief as it may worsen the condition. Therefore, take Chlorthalidone+cilnidipine+telmisartan for as long as your doctor has prescribed it, and if you experience any difficulty while using Chlorthalidone+cilnidipine+telmisartan, please consult your doctor.

    Available Medicines for

    Chlorthalidone+cilnidipine+telmisartan

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