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CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE

About

CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE is a combination medicine used to treat irritable bowel syndrome, peptic ulcers, enterocolitis (swelling in the intestine), and symptoms related to intestinal infection. Irritable bowel syndrome is a common disease that affects the large intestine. Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach protective lining.
 
CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE is a combination of three drugs, namely: Clidinium (anti-cholinergic), Chlordiazepoxide (benzodiazepine), and Dicyclomine (anti-cholinergic). Clidinium works by reducing stomach acid and decreases intestinal spasms. Dicyclomine helps in decreasing stomach cramps and spasms. Chlordiazepoxide decreases abnormal activity in the brain. 
 
You are advised to take CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as weakness, tiredness, dry mouth, nausea, constipation, and drowsiness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Avoid taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you are pregnant or planning for pregnancy, as it may cause birth defects. CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may pass into breastmilk, so avoid taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you are breastfeeding. CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may cause drowsiness, blurred vision or vision changes, do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE as it may cause increased drowsiness. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements.

Uses of CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE

Irritable bowel syndrome, peptic ulcers and enterocolitis.

Medicinal Benefits

CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE is a combination medicine used to treat irritable bowel syndrome, peptic ulcers, enterocolitis (swelling in the intestine), and symptoms related to intestinal infection. CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE is a combination of three drugs, namely: Clidinium, Chlordiazepoxide and Dicyclomine. Clidinium and Dicyclomine belong to a group of medicines called anticholinergics, whereas Chlordiazepoxide belongs to a group of medicines called benzodiazepine. Clidinium works by reducing stomach acid and decreasing intestinal spasms. Dicyclomine helps in decreasing stomach cramps and spasms. Chlordiazepoxide decreases abnormal activity in the brain. 

Directions for Use

Take CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE preferably before meals at bedtime or as advised by the doctor. Swallow CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE as a whole with a glass of water; do not chew, or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE

  • Weakness
  • Tiredness
  • Dry mouth
  • Nausea
  • Constipation
  • Sleepiness
  • Blurred vision
  • Drowsiness

In-Depth Precautions and Warning

Drug Warnings

Do not take CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you are allergic to any of its contents. Inform your doctor before taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you have glaucoma, enlarged prostate, bladder neck obstruction, vision problems, urination problems, depression, liver and kidney problems, if you are 65years or older, if you use opioid (narcotic) medicines such as codeine, hydrocodone, hydromorphone, methadone, morphine, oxycodone, and tramadol. CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may be habit-forming, so inform your doctor if you have a history of drug addiction or abuse. Please do not stop taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE on your own as it might cause withdrawal symptoms. Avoid taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you are pregnant or planning for pregnancy, as it may cause congenital disabilities (birth defects). CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may pass into breastmilk, so avoid taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you are breastfeeding. CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may cause drowsiness, blurred vision or vision changes, do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE as it may cause increased drowsiness. CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE should not be given to children as safety and effectiveness were not established.

Drug Interactions

Drug-Drug Interactions: CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may interact with pain killers (codeine, hydrocodone, hydromorphone, methadone, morphine, oxycodone, tramadol, acetaminophen), blood thinner (warfarin), anti-psychotic (chlorpromazine, fluphenazine, thioridazine), anti-depressants (isocarboxazid, phenelzine, selegiline, tranylcypromine, duloxetine, fluoxetine, sertraline), muscle relaxant (cyclobenzaprine), anti-convulsant (pregabalin, gabapentin), anti-anxiety (alprazolam), antihistamine (cetirizine, diphenhydramine), anti-hypertensive (metoprolol), anti-spasmodic (hyoscyamine), anti-diarrhoeal (loperamide), and anti-emetic (promethazine).

Drug-Food Interactions: Avoid consumption of alcohol while taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE as it may cause increased drowsiness. 

Drug-Disease Interactions: Inform your doctor if you have arrhythmia (irregular heartbeat), gastrointestinal obstruction, glaucoma, infectious diarrhoea, acute alcohol intoxication, drug dependence, autonomic neuropathy (nerve damage), respiratory depression, seizures, prolonged low blood pressure, depression, psychoses, obesity, high blood pressure, porphyria, fever, or tardive dyskinesia (uncontrollable movements of the face).

Drug-Drug Interactions Checker List:

  • CODEINE
  • HYDROCODONE
  • MORPHINE
  • METHADONE
  • OXYCODONE
  • TRAMADOL
  • ACETAMINOPHEN
  • WARFARIN
  • CHLORPROMAZINE
  • FLUPHENAZINE
  • THIORIDAZINE
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • CYCLOBENZAPRINE
  • PREGABALIN
  • GABAPENTIN
  • ALPRAZOLAM
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • METOPROLOL
  • HYOSCYAMINE
  • LOPERAMIDE
  • PROMETHAZINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE as it may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      unsafe

      Consult your doctor before taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE if you are pregnant or planning for pregnancy, as CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may cause birth defects/congenital disabilities.

    • Safety Warning

      Breast Feeding

      unsafe

      CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE is excreted in small amounts in breast milk. Breastfeeding mothers should not take CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE.

    • Safety Warning

      Driving

      unsafe

      CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may cause drowsiness, blurred vision or vision changes. Do not drive or handle machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE should not be given to children as safety and effectiveness were not established.

    Habit Forming

    Yes

    Diet & Lifestyle Advise

    • Eat smaller meals more often.
    • Avoid smoking and alcohol consumption.
    • Maintain a healthy weight by regular exercising.
    • Avoid carbonated and caffeinated beverages.
    • Practise relaxation techniques and avoid stress by doing yoga or meditation.
    • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
    • Avoid deep-fried and spicy foods.
    • Foods containing probiotics may help in providing relief from gas and bloating.

    Patients Concern

    Disease/Condition Glossary

    Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods and beverages, irregular hormone levels, certain food and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea. 

    Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

    Enterocolitis: It is an inflammation of the digestive tract caused by bacteria, virus, parasites, fungus, or other causes. Symptoms include loss of appetite, nausea, vomiting, abdominal pain, mucus-like discharge from the rectum and diarrhoea.

    FAQs

    CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE is a combination of three drugs, namely: Clidinium (anti-cholinergic), Chlordiazepoxide (benzodiazepine) and Dicyclomine (anti-cholinergic). Clidinium works by reducing stomach acid and decreases intestinal spasms. Dicyclomine helps in decreasing stomach cramps and spasms. Chlordiazepoxide decreases abnormal activity in the brain.

    Constipation might be a side-effect of CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE. Drink enough fluids and eat fibre-rich food if you experience constipation. Consult your doctor if the condition persists or worsens.

    Please do not stop taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE on your own as it might cause withdrawal symptoms such as fits, shaking, muscle cramps, stomach cramps, depression, vomiting, sleeping problems, and sweating. Consult your doctor if you experience any difficulty while taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE, the doctor may gradually reduce the dose.

    Dry mouth could be a side-effect of CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

    Irregular menstrual cycle might be a side-effect of CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE. Consult your doctor if you miss your periods or if you have irregular periods while taking CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE.

    CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE may be a habit-forming, especially in people with a history of drug addiction or abuse and in those who are alcoholic. Take CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE only as prescribed by the doctor. Do not share CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE with others.

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    CLIDINIUM+CHLORDIAZEPOXIDE+DICYCLOMINE

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