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Clobetasol+clotrimazole+fusidic Acid

About

Clobetasol+clotrimazole+fusidic Acid belongs to the class of ‘Topical steroid with antifungal and antibacterial agents’, primarily used to treat skin infections, such as eczema (inflamed, itchy, cracked and rough skin patches), dermatitis (inflammation of the skin), psoriasis (skin cells multiply rapidly to form bumpy (uneven) red patches covered with white scales), ringworm, athlete's foot, jock itch, lichen planus (inflammation of the skin and mucous membranes) and tinea versicolor (discoloured patches on the skin). Skin infection occurs when a foreign microbe like fungus or bacteria invades and affects the skin's tissue.

Clobetasol+clotrimazole+fusidic Acid consists of three medicines, namely: Clobetasol (corticosteroid), Clotrimazole (antifungal) and Fusidic acid (antibacterial). Clobetasol is a highly potent ‘corticosteroid’ with anti-inflammatory, antipruritic (relieves itching) and vasoconstrictive (narrows blood vessels) properties. It blocks the production of chemical mediators of inflammation (such as kinins, histamine, liposomal enzymes, and prostaglandins) that make the skin red, swollen and itchy. Clotrimazole is an ‘antifungal’ medication. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane. On the other hand, Fusidic acid is an ‘antibacterial’ medication that prevents the synthesis of essential proteins required by bacteria to carry out vital functions.

Clobetasol+clotrimazole+fusidic Acid is for external use only. Use this medication on the skin only as advised by the doctor. Common side effects of Clobetasol+clotrimazole+fusidic Acid are burning, irritation, itching, redness and thinning of skin at the application site. These side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Avoid contact with your eyes, nose or mouth while using Clobetasol+clotrimazole+fusidic Acid. Rinse it off with water thoroughly if you get the medicine in these areas. Brief your medical history to the doctor if you are allergic to Clobetasol+clotrimazole+fusidic Acid or any of its components. Therapy with topical corticosteroids like Clobetasol should be administered cautiously in patients with bacterial, fungal, viral and protozoa infections. Let your doctor know if you have any medical history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases. Please consult your doctor if you are a pregnant or breastfeeding woman before using Clobetasol+clotrimazole+fusidic Acid.

Uses of Clobetasol+clotrimazole+fusidic Acid

Skin infections, eczema, psoriasis, dermatitis, tinea versicolor, lichen planus, ringworm, athlete's foot and jock itch.

Medicinal Benefits

Clobetasol+clotrimazole+fusidic Acid treats various skin infections and is a combination of three medicines: Clobetasol, Clotrimazole, and Fusidic acid. Clobetasol is a corticosteroid with anti-inflammatory, antipruritic and vasoconstrictive properties. It blocks the production of chemical mediators of inflammation that make the skin red, swollen and itchy. It works by relieving inflammation and itching caused by plaque psoriasis and other skin conditions. Clotrimazole is an antifungal medication that stops fungi's growth by causing damage and leakage to the fungal cell membrane. Fusidic acid is an antibacterial/antibiotic that prevents the synthesis of essential proteins required by bacteria to carry out vital functions. It is used to treat infections like dermatitis, spots, cuts, grazes, impetigo (weeping, crusty and swollen patch of skin) and folliculitis (inflammation of one or more hair follicles).

Directions for Use

Cream/ointment: Take a small amount of the cream/ointment on the fingertip and apply it as a thin layer on the clean and dry affected area as prescribed by your doctor. Do not use it on the face, and avoid contact with the eyes, mouth and nose.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clobetasol+clotrimazole+fusidic Acid

  • Burning 
  • Irritation 
  • Itching 
  • Redness 
  • Thinning of skin 

In-Depth Precautions and Warning

Drug Warnings

Brief your medical history to doctor, if you are allergic to Clobetasol+clotrimazole+fusidic Acid or any of its components. Therapy with topical corticosteroids like Clobetasol should be administered cautiously in patients with bacterial, fungal, viral and protozoa infections. Let your doctor know if you have any history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases. Clobetasol+clotrimazole+fusidic Acid is not recommended for diaper rash. If you are pregnant or breastfeeding, you should use Clobetasol+clotrimazole+fusidic Acid with proper doctor consultation and caution. Do not use Clobetasol+clotrimazole+fusidic Acid on the face and avoid contact with eyes, nose and throat. Rinse it off with water thoroughly if you get the cream/ointment in these areas. Do not put a bandage or a dressing on the affected area while using Clobetasol+clotrimazole+fusidic Acid unless advised by the doctor. Always wash hands before and after application of Clobetasol+clotrimazole+fusidic Acid. Do not store Clobetasol+clotrimazole+fusidic Acid above 25°C.

Drug Interactions

Drug-Drug Interaction: Clobetasol+clotrimazole+fusidic Acid may interact with other corticosteroids (prednisone), respiratory-related medicines (budesonide, formoterol), and drugs that lower the immune system (cyclosporine).

Drug-Food Interaction: No interactions found. However, it is advised to limit the intake of alcohol.

Drug-Disease Interaction: Clobetasol+clotrimazole+fusidic Acid is contraindicated in fungal, viral, protozoa infections, liver and kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes, and adrenal gland diseases.

Drug-Drug Interactions Checker List:

  • PREDNISONE
  • BUDESONIDE
  • FORMOTEROL
  • CYCLOSPORINE
  • Safety Advice

    • Safety Warning

      Alcohol

      safe if prescribed

      No interaction found of Clobetasol+clotrimazole+fusidic Acid with alcohol.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are planning to become pregnant or already pregnant before starting Clobetasol+clotrimazole+fusidic Acid.

    • Safety Warning

      Breast Feeding

      caution

      It is not known if Clobetasol+clotrimazole+fusidic Acid passes into the breast milk. Please consult your doctor before taking Clobetasol+clotrimazole+fusidic Acid if you are breastfeeding. If you need to apply the cream or ointment on your breasts, don't do this shortly before giving a feed.

    • Safety Warning

      Driving

      safe if prescribed

      There have been no studies to investigate the effect of Clobetasol+clotrimazole+fusidic Acid on driving performance or the ability to operate machinery.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Clobetasol+clotrimazole+fusidic Acid.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases before taking Clobetasol+clotrimazole+fusidic Acid. Your doctor will weigh the benefits and potential risks before prescribing Clobetasol+clotrimazole+fusidic Acid.

    • Safety Warning

      Children

      caution

      Clobetasol+clotrimazole+fusidic Acid is not recommended for children less than two years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Use mild soap while taking baths and prefer warm baths.
    • Avoid harsh products on your skin.
    • Do not scratch or pick your skin to avoid getting the affected area infected.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep. 

    Special Advise

    • It is advised to reach out to your doctor if the skin infection symptoms persist or worsen after two treatment weeks. 
    • Corticosteroids like Clobetasol may affect blood sugar levels. Please monitor your blood glucose levels regularly if you have diabetes and using Clobetasol+clotrimazole+fusidic Acid. 
    • Clotrimazole in Clobetasol+clotrimazole+fusidic Acid may cause abnormal liver functions tests in people with liver impairment. Please let your doctor know if you have any history of liver diseases before undergoing liver function tests and using Clobetasol+clotrimazole+fusidic Acid.

    Patients Concern

    Disease/Condition Glossary

    Skin infection: Skin infection occurs when a foreign microbe like fungus or bacteria invades and affects the skin's tissue.

    Athlete's foot: It is a fungal infection between the toes due to sweating.

    Jock itch: A fungal infection in the skin of the genitals, inner thighs and buttocks.

    Eczema: It is a condition in which skin patches become inflamed, itchy, cracked and rough.

    Psoriasis: It is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales.

    Dermatitis is a skin condition that causes itchy, dry skin or a rash on swollen, reddened skin.

    FAQs

    Clobetasol+clotrimazole+fusidic Acid contains Clobetasol, Clotrimazole and Fusidic acid. Clobetasol is a corticosteroid that provides relief from itching and redness of infection. Clotrimazole and Fusidic acid are antibiotics that treat and prevent various fungal and bacterial skin infections by inhibiting microbial growth.

    Clobetasol+clotrimazole+fusidic Acid is for topical (for skin use) application only. Do not use Clobetasol+clotrimazole+fusidic Acid on the face and avoid contact with eyes. Do not put a bandage or a dressing on the affected area while using Clobetasol+clotrimazole+fusidic Acid unless advised by the doctor.

    Clobetasol+clotrimazole+fusidic Acid should be used with proper caution and doctor consultation if you have any bacterial, fungal, viral and protozoa infections, liver or kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases.

    Do not stop using Clobetasol+clotrimazole+fusidic Acid even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.

    Clobetasol+clotrimazole+fusidic Acid, when used for longer periods, can cause thinning and weakening of the skin. Please stop using Clobetasol+clotrimazole+fusidic Acid and immediately consult your doctor if you notice these symptoms.

    Available Medicines for

    Clobetasol+clotrimazole+fusidic Acid

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