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Clonazepam+paracetamol

About

Clonazepam+paracetamol is a combination of two drugs: clonazepam and Paracetamol. Clonazepam is a Benzodiazepines (BZD) that are primarily used to treat anxiety disorders, restless leg syndrome, and prevention of seizures (fits) due to epilepsy. An anxiety disorder is a mental health disorder characterized by feelings of excessive fear or worry that affects an individual's daily activities. On the other hand, Epilepsy is a chronic disorder characterized by episodes of seizures (fits). Restless leg syndrome is a disorder that causes an uncontrollable need to move your legs, generally because of an unpleasant sensation. It usually happens in the evening or night-time when you are sitting or lying down. Whereas paracetamol is a common pain killer. It also has an antipyretic effect (reduces fever).

Clonazepam+paracetamol is composed of two medicines: clonazepam (reduce anxiety) and Paracetamol (reduce pain, inflammation, and fever). Clonazepam works by increasing levels of brain cell (neuron) calming chemical, known as gamma-amino-butyric-acid (GABA) in your brain that helps to relieve anxiety, stop seizures attacks (fits), and cause relaxation of the tense muscles. Besides this, Clonazepam+paracetamol also relieves temporary insomnia (sleeplessness) due to anxiety disorders. Paracetamol has both analgesic and antipyretic (fever reducer) properties which decrease mild pain and possibly fever. Therefore, paracetamol minimizes pain and inflammation in these conditions.

Take Clonazepam+paracetamol as prescribed by your doctor. You are advised to take Clonazepam+paracetamol for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience altered walking, dizziness, depression, drowsiness, lack of coordination, fatigue, memory loss. Most of these side effects of Clonazepam+paracetamol do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorders or difficulty sleeping (sleep apnoea), severe liver disease, or a problem with alcohol or other prescription drugs. Clonazepam+paracetamol is a habit-forming drug and, hence there is a risk of forming a dependence on this medicine. Therefore, before stopping this medicine, consult your doctor to cause withdrawal symptoms like anxiety, increased heart rate, tremor, or general unwell feeling.

Uses of Clonazepam+paracetamol

Anxiety disorder, Epilepsy, Restless leg syndrome

Medicinal Benefits

When you take Clonazepam+paracetamol, it will increase chemical messenger (GABA neurotransmitter) in your body, which helps decrease the feeling of nervousness, stress, and anxiety, leading to calm and relaxation. Clonazepam+paracetamol benefits people who struggle with anxiety and worries in daily life. Clonazepam+paracetamol contains ‘paracetamol’ which reduces pain and inflammation in these conditions. Paracetamol has less gastric irritation than other painkillers. Regular intake of the prescribed dose of Clonazepam+paracetamol improves social life and your ability and performance at work and general wellbeing. Besides this, it also relieves the symptoms of restless leg syndrome by relaxing the muscle. Clonazepam+paracetamol causes a relaxing effect on the brain, which may help control the body's movements.

Directions for Use

Swallow Clonazepam+paracetamol as a whole with a full glass of water. It should be taken with or without food. Do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clonazepam+paracetamol

  • Altered walking
  • Dizziness
  • Depression
  • Drowsiness
  • Lack of coordination
  • Fatigue
  • Memory loss

In-Depth Precautions and Warning

Drug Warnings

Taking Clonazepam+paracetamol with opioid medicines can cause severe drowsiness, breathing problems, coma, and death. Clonazepam+paracetamol should be taken with extreme caution in patients with a history of alcohol or drug abuse. Clonazepam+paracetamol may affect your ability to drive or operate heavy machinery if taken with alcohol. If you feel excess suicidal thoughts, difficulty in concentration, sleep disturbances, dizziness, or, sleepiness let your doctor know about this. Do not take Clonazepam+paracetamol if you are allergic to paracetamol and, any benzodiazepine class of drugs (diazepam, chlordiazepoxide, bromazepam, or flurazepam), suffer from lung disease, liver disease, kidney disease, glaucoma, muscle weakness (myasthenia gravis), or have difficulty in sleeping (sleep apnoea). Pregnant or lactating women should consult a doctor before taking it as Clonazepam+paracetamol contains clonazepam, a Category D pregnancy medication.

Drug Interactions

Drug-Drug Interactions: Clonazepam+paracetamol may have interaction with antianxiety or antiepileptic medicines (like carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), blood thinner (warfarin), anti-HIV drugs (like amprenavir, ritonavir), acidity medicine (like cimetidine), (metoclopramide or domperidone), disulfiram (to treat chronic alcoholism), anti TB drug (like rifampicin), anti-Parkinson’s drug (like levodopa), and asthma drugs (like theophylline). Besides this, central nervous system depressant drugs should be avoided with Clonazepam+paracetamol as may cause serious side effects.

Drug-Food Interactions: Avoid alcohol as it may increase the risk of side-effects when taken along with Clonazepam+paracetamol.

Drug-Disease Interactions: Obese people (with a BMI greater than 25), respiratory depression, drug dependence, seizures, depression, suicidal tendency, closed-angle glaucoma and renal/liver disease patients should consult a doctor before taking Clonazepam+paracetamol.

Drug-Drug Interactions Checker List:

  • CARBAMAZEPINE
  • FLUVOXAMINE
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • WARFARIN
  • AMPRENAVIR
  • RITONAVIR
  • CIMETIDINE
  • METOCLOPRAMIDE
  • DISULFIRAM
  • DOMPERIDONE
  • RIFAMPICIN
  • LEVODOPA
  • THEOPHYLLINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended not to consume alcohol along with Clonazepam+paracetamol to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

    • Safety Warning

      Pregnancy

      caution

      Clonazepam+paracetamol contains clonazepam which is a Category D risk pregnancy drug that is considered unsafe for pregnant women. Clonazepam+paracetamol can have some harmful effects on the baby (fetus), so your doctor will weigh the benefits and any potential risks before prescribing it to you.

    • Safety Warning

      Breast Feeding

      unsafe

      Clonazepam+paracetamol passes into the breast milk and may cause some degree of sedation in the baby. So, keep your doctor informed if you're planning to breastfeed while on Clonazepam+paracetamol.

    • Safety Warning

      Driving

      unsafe

      Clonazepam+paracetamol usually causes dizziness, drowsiness and visual disturbances which may affect their ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Clonazepam+paracetamol. Tell your doctor if you get these types of side effects.

    • Safety Warning

      Liver

      caution

      Clonazepam+paracetamol to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Clonazepam+paracetamol to be taken with caution, especially if you have a history of kidney disorders. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      It is not known whether if Clonazepam+paracetamol is safe or effective in treating conditions like panic disorder in children younger than 18 years old. So, your doctor will decide whether Clonazepam+paracetamol can be given to children less than 18 years of age or not.

    Habit Forming

    Yes

    Diet & Lifestyle Advise

    • Do regular exercise which can help lower anxiety by releasing endorphins and improving your sleep and self-image.
    • Find the humour in your daily life. Try to watch light-hearted shows to help relieve stress.
    • You can try increasing your mindfulness, by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
    • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
    • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
    • Herbs like turmeric, ginger, and chamomile contain anti-inflammatory properties. Including these stuff in meals can reduce inflammation caused due to anxiety disorder.
    • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake. Especially trans-fat may help also help reduce inflammation.
    • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
    • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

    Special Advise

    • Clonazepam+paracetamol causes drowsiness. Avoid doing activities that require your complete focus and attention like driving when on this drug.
    • An abrupt stoppage of Clonazepam+paracetamol can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
    • Avoid consuming alcohol while on this medication as it can lead to dangerous side effects.
    • Clonazepam+paracetamol is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
    • To avoid getting addicted to this drug take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

    Patients Concern

    Disease/Condition Glossary

    Epilepsy: It is a chronic disorder characterized by episodes of seizures (fits) which means sudden jerky movements of limbs or other body parts. Epilepsy should not be confused with an anxiety disorder. Epilepsy should not be confused with an anxiety disorder.

    Anxiety: It can cause panic attacks, with intense feelings of nervousness, fear, and sudden onset of sweating, hyperventilation, fast heartbeat, and flushing of the skin. Anyone can develop epilepsy, but it is commonly seen in young children and the elderly.

    Restless leg syndrome: It is a disorder that causes an uncontrollable need to move your legs, generally because of an unpleasant sensation. It usually happens in the evening or night-time when you are sitting or lying down.

    FAQs

    Clonazepam+paracetamol decreases the activity in the brain producing a calming effect. It improves mood, behaviour, and cognition in patients with anxiety.

    There is no clinical evidence that Clonazepam+paracetamol affects fertility in either men or women. But, if you are trying to get pregnant, consult your doctor.

    Clonazepam+paracetamol belongs to a class of medicines called benzodiazepines and is used to treat stop seizures (fits), anxiety, or relax tense muscles. This can also help relieve trouble sleeping (insomnia) and is generally prescribed for a short period of time if used to treat sleeping difficulties. You should take it in the dose and duration recommended by the doctor.

    Do not stop taking Clonazepam+paracetamol until instructed by your doctor. You may get side effects like confusion, depression, nervousness, sweating, and diarrhoea. Your doctor may lower the dose of Clonazepam+paracetamol if using it for more than 2-4 weeks of treatment to reduce side effects.

    Yes. Memory loss is a common side effect of Clonazepam+paracetamol. So, regular intake of Clonazepam+paracetamol can impact your memory and cause lack of concentration, or even complete ‘blackout’ and difficulty in remembering important things.

    Anxiety is a feeling of fear, worry, or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling, and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.

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