Codeine+triprolidine
About
Codeine+triprolidine belongs to a class of medication called ‘cough and cold preparations’ primarily used to treat dry cough associated with a common cold or upper respiratory allergies. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.
Codeine+triprolidine is a combination of two drugs: Codeine (cough suppressant) and Triprolidine(antihistamine). Codeine belongs to the class of cough suppressants that blocks the μ-opioid receptor in the brain that produces cough, thereby decreasing the urge to cough. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Take Codeine+triprolidine as prescribed by your doctor. Take Codeine+triprolidine for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain side effects, including drowsiness, dry mouth, vomiting, blurred vision, constipation, dizziness, or tiredness. Most of these side effects of Codeine+triprolidine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Please tell your doctor if you are allergic to Codeine+triprolidine or any other medicines. Drink plenty of fluids while taking Codeine+triprolidine to loosen mucus and protect yourself from being dehydrated or overheated during exercise. In hot weather, as Codeine+triprolidine contains Triprolidine, it decreases sweating and increases heatstroke risk. Do not take Codeine+triprolidine if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Codeine+triprolidine is not recommended for children below 18 years of age. Do not take Codeine+triprolidine if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days, as it may cause life-threatening drug interaction. Codeine+triprolidine is a habit-forming drug, and hence there is a risk of dependence on Codeine+triprolidine. So, before stopping Codeine+triprolidine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feelings.
Uses of Codeine+triprolidine
Medicinal Benefits
Codeine+triprolidine is a combination of two drugs: Triprolidine and Codeine. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Codeine belongs to the class of narcotic cough suppressants that block the μ-opioid receptor in the brain that produces cough, thereby decreasing the urge to cough. Codeine+triprolidine is used to treat cough associated with a common cold or upper respiratory allergies.
Directions for Use
Storage
Side Effects of Codeine+triprolidine
- Dizziness/Drowsiness
- Mood changes
- Tiredness/weakness
- Nausea and Vomiting
- Increased heartbeat
- Loss of appetite
- Headache
- Blurred vision
- Dry mouth
- Constipation
- Urinary retention
- Coordination problems
In-Depth Precautions and Warning
Drug Warnings
Please tell your doctor if you are allergic to Codeine+triprolidine or any other medicines. Do not take Codeine+triprolidine for a prolonged time, Codeine+triprolidine contains codeine that may lead to mental or physical dependence on Codeine+triprolidine. Do not take Codeine+triprolidine if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Codeine+triprolidine is not recommended for children below 18 years of age. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, as a dangerous drug interaction could occur. Codeine+triprolidine should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Drink plenty of fluids while taking Codeine+triprolidine to loosen mucus and protect yourself from being dehydrated or overheated during exercise. In hot weather, as Codeine+triprolidine contains Triprolidine, it decreases sweating and increases heatstroke risk. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, kidney, liver, heart or urinary problems, inform your doctor before taking Codeine+triprolidine.
Drug Interactions
Drug-Drug Interaction: Codeine+triprolidine may have interaction with anti-allergic drugs (diphenhydramine, cetirizine, brompheniramine, diphenhydramine, fexofenadine), cough suppressants (dextromethorphan), antidepressants (duloxetine, sertraline, paroxetine, fluvoxamine, trazodone), narcotic analgesics (hydrocodone, bupropion, morphine, oxycodone) and antianxiety drug (alprazolam, diazepam, lorazepam, oxazepam, temazepam), fits related drugs (phenytoin, clonazepam, carbamazepine).
Drug-Food Interaction: Codeine+triprolidine may interact with alcohol. Therefore, avoid alcohol consumption with Codeine+triprolidine as it may increase the risk of fatal side effects such as drowsiness, dizziness, slow breathing, or death.
Drug-Disease Interaction: If you have chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), drug dependence, high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Codeine+triprolidine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Codeine+triprolidine as it may increase the risk of drowsiness and other adverse effects.
Pregnancy
unsafeCodeine+triprolidine is not recommended for use during pregnancy. Codeine+triprolidine can have some harmful effects on the baby (fetus). Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing it.
Breast Feeding
unsafeCodeine+triprolidine may be excreted in breast milk and cause harm to your infant. Therefore, Codeine+triprolidine should not be used while breastfeeding without a doctor’s advice.
Driving
unsafeCodeine+triprolidine may cause dizziness, drowsiness, blurred vision, or impaired thinking in some people. Therefore, drive only if you are alert after taking Codeine+triprolidine.
Liver
cautionTake Codeine+triprolidine with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor if required.
Kidney
cautionTake Codeine+triprolidine with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeCodeine+triprolidine is not recommended for children below 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
- Drink plenty of fluids to avoid dry throat while you cough and loosen mucus.
- Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches, and pineapples.
Special Advise
- Do not take Codeine+triprolidine for a prolonged time as it may lead to mental or physical dependence on Codeine+triprolidine.
- To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
- Codeine+triprolidine causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
- An abrupt stoppage of Codeine+triprolidine can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
- Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.
- Codeine+triprolidine is unsafe for usage if you're pregnant or plan to get pregnant and breastfeed. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
Patients Concern
Disease/Condition Glossary
Cough: Coughing is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or minor infections in the respiratory tract, and yellow or green mucus indicates a respiratory infection.
FAQs
Codeine+triprolidine is a combination of two drugs: Triprolidine and Codeine, which relieves dry cough. Triprolidine is an antihistaminic that blocks a chemical messenger (histamine) that may trigger a cough due to an allergy. Codeine is a cough suppressant. It suppresses cough by reducing the activity of the cough centre in the brain.
Do not take Codeine+triprolidine with 'alprazolam' as co-administration of these two medicines may increase adverse effects such as sedation, respiratory depression, coma, and death. However, please consult a doctor before taking Codeine+triprolidine with other medicines.
Codeine+triprolidine is excreted in breast milk and may cause drowsiness, breathing problems, or death in a nursing baby. Therefore, if you are breastfeeding, please inform your doctor before taking Codeine+triprolidine. Your doctor will weigh the benefits and any potential risks before prescribing Codeine+triprolidine to you.
Codeine+triprolidine is not recommended for children below 18 years of age as a misuse of Codeine+triprolidine in children may lead to serious adverse effects. Codeine in Codeine+triprolidine may cause life-threatening respiratory depression and death in children who recently had surgery to remove the tonsils or adenoids.
Codeine+triprolidine may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes. Codeine+triprolidine contains Triprolidine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Codeine+triprolidine is unsafe to use in pregnancy. Codeine+triprolidine contains Triprolidine, If you use Codeine+triprolidine while pregnant, your baby could become dependent on codeine. This can cause life-threatening withdrawal symptoms in the baby after it is born.
Yes, Triprolidine in Codeine+triprolidine may cause mental or physical dependence if used for a prolonged time. Therefore, take Codeine+triprolidine only in dose and duration as advised by your doctor.
