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Cyclobenzaprine+aceclofenac

About

Cyclobenzaprine+aceclofenac belongs to a class of medicine known as a pain killer. It is primarily used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis (joint pain), gout, pinched vein, acute pain and chronic pain, muscle spasms. It relieves the pain and relaxes the muscles. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Cyclobenzaprine+aceclofenac is a combination of two drugs: Cyclobenzaprine (muscle relaxant) and aceclofenac (NSAID). Cyclobenzaprine is a muscle relaxant and works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. Aceclofenac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins (PG). By blocking the effect of chemical messenger aceclofenac helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Take Cyclobenzaprine+aceclofenac as prescribed by your doctor. You are advised to take Cyclobenzaprine+aceclofenac for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, dryness in the mouth, stomach pain, diarrhea, heartburn, loss of appetite (feeling not hungry), dizziness and sleepiness. Most of these side effects of Cyclobenzaprine+aceclofenac do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Cyclobenzaprine+aceclofenac if you are allergic to Cyclobenzaprine+aceclofenac or any of its contents. Cyclobenzaprine+aceclofenac should not be taken in the conditions like liver disease, kidney disease, asthma and high blood pressure. Cyclobenzaprine+aceclofenac may cause drowsiness, sleepiness, fatigue, dizziness and visual disturbance it is advisable to you do not drive unless you are alert. If you are pregnant or breastfeeding, please inform your doctor before starting Cyclobenzaprine+aceclofenac. Cyclobenzaprine+aceclofenac should not be used in children below 18 years of age as safety and efficacy have not established.

Uses of Cyclobenzaprine+aceclofenac

Osteoarthritis, Rheumatoid arthritis, Gouty arthritis, Pinched vein, Ankylosing spondylitis, Acute pain, Chronic low back pain, Muscle spasms.

Medicinal Benefits

Cyclobenzaprine+aceclofenac is a combination of two drugs: Cyclobenzaprine (muscle relaxant) and aceclofenac (NSAID). Cyclobenzaprine+aceclofenac is used for the treatment of osteoarthritis, rheumatoid arthritis, gout and ankylosing spondylitis, pinched vein, acute pain, chronic low back pain and muscle spasms. Cyclobenzaprine works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. Aceclofenac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandin' (PG). These chemicals are produced at injury sites and cause pain and swelling. By blocking the effect of chemicals, aceclofenac helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thus, Cyclobenzaprine+aceclofenac relieves the pain and relax the muscles.

Directions for Use

Take Cyclobenzaprine+aceclofenac with or after food. Swallow it as a whole with a glass of water, do not chew or break it. Based on your medical condition, your doctor will decide how long you need to take Cyclobenzaprine+aceclofenac.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cyclobenzaprine+aceclofenac

  • Nausea
  • Dryness in mouth
  • Stomach pain
  • Diarrhea
  • Heartburn
  • Loss of appetite (feeling not hungry)
  • Dizziness
  • Sleepiness.

In-Depth Precautions and Warning

Drug Warnings

Cyclobenzaprine+aceclofenac should not be taken if you are known to be allergic to Cyclobenzaprine+aceclofenac or any other medicines. Cyclobenzaprine+aceclofenac can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Cyclobenzaprine+aceclofenac. Inform your doctor if you have thyroid disorder (hyperthyroidism), stomach ulcers, have suffered bleeding problems, clotting problems, severe heart, liver or kidney problems.  Please talk to your doctor immediately if you experience mood swings, depression or if you have any suicidal thoughts. Your doctor may advise you to undergo regular blood tests to monitor liver function. Inform your doctor before taking Cyclobenzaprine+aceclofenac if you have or had disorders of the stomach, blood circulation problem to brain, asthma, porphyria, diabetes, high blood pressure. Cyclobenzaprine+aceclofenac may cause drowsiness, sleepiness, fatigue, dizziness and visual disturbance it is advisable to you do not drive unless you are alert. If you are pregnant or breastfeeding, please inform your doctor before starting Cyclobenzaprine+aceclofenac. Cyclobenzaprine+aceclofenac should not be used in children below 18 years of age as safety and efficacy have not established.

Drug Interactions

Drug-Drug Interactions: Cyclobenzaprine+aceclofenac may have interaction with heart disease (digoxin), pain killer (aspirin, morphine), blood thinner (clopidogrel), antiparkinson’s disease (selegiline), antidepressant (lithium), blood pressure-lowering medicines (captopril), water pills/diuretics (amiloride), medicines for skin disease (tacrolimus), antiallergic (chlorpheniramine), sleeping pill (zolpidem).

Drug-Food Interactions: Avoid alcohol consumption while taking Cyclobenzaprine+aceclofenac as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Cyclobenzaprine+aceclofenac may have interactions with allergy, kidney disease, asthma, ulcer and heart disease.

Drug-Drug Interactions Checker List:

  • DIGOXIN
  • ASPIRIN
  • MORPHINE
  • CLOPIDOGREL
  • SELEGILINE
  • LITHIUM
  • CAPTOPRIL
  • AMILORIDE
  • TACROLIMUS
  • CHLORPHENIRAMINE
  • ZOLPIDEM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Cyclobenzaprine+aceclofenac as it may increase drowsiness. It can also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      Avoid taking Cyclobenzaprine+aceclofenac if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Very-small amounts of Cyclobenzaprine+aceclofenac pass into breast milk. However, consult your doctor before taking Cyclobenzaprine+aceclofenac, your doctor will decide whether Cyclobenzaprine+aceclofenac can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Cyclobenzaprine+aceclofenac may cause drowsiness, sleepiness, fatigue, dizziness and visual disturbance it is advisable to you do not drive unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Avoid taking Cyclobenzaprine+aceclofenac if you have severe kidney disease.

    • Safety Warning

      Children

      unsafe

      Cyclobenzaprine+aceclofenac should not be given to children for 18 years of age as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
    • Performing yoga may also help in improving joint flexibility and pain management.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
    • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
    • Acupuncture, massage and physical therapy may also be helpful.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Avoid smoking and alcohol consumption.

    Special Advise

    Cyclobenzaprine+aceclofenac is not recommended for use in patients with a history of gastrointestinal ulcers or bleeding since it may worsen the patient's condition.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

    Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

    Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

    Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to hunched-forward posture, pain and back and joints.

    Gout: It is caused due to deposits of uric acid crystals in the joints, which leads to pain and inflammation in the joints. Symptoms include pain, swelling and redness in the joints, mostly the big toe.

    FAQs

    Cyclobenzaprine+aceclofenac is a combination of two drugs: Cyclobenzaprine (Muscle relaxant) and aceclofenac (NSAID). Cyclobenzaprine works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. Aceclofenac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandin' (PG). These chemicals are produced at injury sites and cause pain and swelling. By blocking the effect of chemicals, aceclofenac helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thus, Cyclobenzaprine+aceclofenac relieves the pain and relax the muscles.

    Diarrhea might be a side-effect of Cyclobenzaprine+aceclofenac. Drink enough fluids and eat fiber-rich food if you experience diarrhea. Inform your doctor if diarrhea continues and you observe signs of dehydration, like dark colored with less urination and strong-smelling urine. Do not take anti-diarrheal medicine on your own.

    Yes, the use of Cyclobenzaprine+aceclofenac can lead to dry mouth. If you feel dry mouth, drink plenty of water. If your lips are also dry you may use lip balm. Try to prevent foods that are spicy, salty and acidic (like lemons).

    Cyclobenzaprine+aceclofenac is normally used for the short term and can be stopped if there is no pain. Although, it should be persisted if recommended by the doctor.

    Ankylosing spondylitis is arthritis of the spine that can lead to the fusion of the vertebrae, leading to pain and inflammation in the spine.

    Available Medicines for

    Cyclobenzaprine+aceclofenac

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