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ETHINYLESTRADIOL+CYPROTERONE

About

CYPROTERONE+ETHINYLESTRADIOL is an oral hormonal combination, containing Ethinylestradiol and Cyproterone used to treat symptoms of polycystic ovary syndrome (PCOS) such as acne, excessive hair growth (hirsutism), and irregular periods. Polycystic ovary syndrome is a common condition, which affects how women's ovaries work. 

CYPROTERONE+ETHINYLESTRADIOL is a combination of two hormonal medications, ethinylestradiol, and cyproterone used to treat PCOS symptoms such as acne, excessive hair growth (hirsutism), and irregular periods. Cyproterone, works by blocking a male hormone named androgen overproduction in the ovaries and reducing unwanted facial hair growth and acne. Ethinylestradiol, on the other hand, acts as an enhancer. It enhances the effect of cyproterone by reducing the amount of androgens in the blood. Collectively, they both effectively treat the symptoms of PCOS.

CYPROTERONE+ETHINYLESTRADIOL can be taken with or without food in dose and duration as prescribed by your doctor. For best results of CYPROTERONE+ETHINYLESTRADIOL, take it at the same time every day. Also, do not stop taking CYPROTERONE+ETHINYLESTRADIOL before completing its full course, even if you feel your symptoms are better. The most common side effects of CYPROTERONE+ETHINYLESTRADIOL include weight gain, nausea, tender breast, stomach pain, and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you see swelling or pain in your limbs, chest pain, or shortness of breath, please inform your doctor.

Inform your doctor if your periods do not start within a week after taking CYPROTERONE+ETHINYLESTRADIOL. Do not take CYPROTERONE+ETHINYLESTRADIOL if you are pregnant already or breastfeeding. CYPROTERONE+ETHINYLESTRADIOL does not prevent the transmission of any sexually transmitted disease (STD), so use some other form of contraception (condom) during sexual intercourse if you have any STD or AIDS (acquired immunodeficiency syndrome). If you have any blood clots, please consult your doctor as CYPROTERONE+ETHINYLESTRADIOL may not be prescribed.

Uses of ETHINYLESTRADIOL+CYPROTERONE

 Polycystic ovary syndrome (PCOS).

Medicinal Benefits

CYPROTERONE+ETHINYLESTRADIOL is a combination of two hormonal drugs, ethinylestradiol, and cyproterone. It is used to treat PCOS symptoms such as acne, excessive hair growth (hirsutism), and irregular periods. Cyproterone works by blocking a male hormone named androgen overproduction in the ovaries and reducing unwanted facial hair growth and acne. Ethinylestradiol, on the other hand, acts as an enhancer. It enhances the effect of cyproterone by reducing the amount of androgens in the blood. Collectively, they both effectively treat the symptoms of PCOS.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Your doctor will suggest on how you take the course of CYPROTERONE+ETHINYLESTRADIOL.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ETHINYLESTRADIOL+CYPROTERONE

  • Weight gain
  • Nausea
  • Tender breast
  • Stomach pain
  • Headache
  • Mood changes

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to CYPROTERONE+ETHINYLESTRADIOL, please inform your doctor. Please undergo regular cervical smear test while taking CYPROTERONE+ETHINYLESTRADIOL. Also, check your breast every month for changes such as if you feel lumps, see anything odd, please inform your doctor. If you need to undergo any surgery, please inform your doctor as CYPROTERONE+ETHINYLESTRADIOL needs to be stopped 4-6 weeks before the surgery to avoid any risk of blood clots. If you smoke, are obese, have a history of blood clots, do not use CYPROTERONE+ETHINYLESTRADIOL. Also, do not stop taking CYPROTERONE+ETHINYLESTRADIOL before completing its full course, even if you feel your symptoms are better. If you see swelling or pain in your limbs, chest pain, or shortness of breath, please inform your doctor. Inform your doctor if your periods do not start within a week after taking CYPROTERONE+ETHINYLESTRADIOL. Also, tell about all the medicines you are taking to your doctor before starting CYPROTERONE+ETHINYLESTRADIOL. Do not take CYPROTERONE+ETHINYLESTRADIOL if you are pregnant already or breastfeeding. If you have missed a dose or are late by 12 hours, please wear a condom for 2 days while sexual intercourse to avoid unwanted pregnancy.

Drug Interactions

Drug-Drug interaction: CYPROTERONE+ETHINYLESTRADIOL may interact with anti-fungal medicine (griseofulvin, rifampicin), anti-viral medicines (ritonavir, nelfinavir, nevirapine), anti-epileptic (lamotrigine), anti-epilepsy medicines(primidone, phenytoin, carbamazepine, oxcarbazepine, topiramate).

Drug-Food Interaction: CYPROTERONE+ETHINYLESTRADIOL may interact with St. John’s Wort (a herbal remedy for depression).

Drug-Disease Interaction: Inform your doctor if you have or ever had liver or kidney problems, hypertension, heart problem, blood clot in any body part (lung, leg), diabetes mellitus, migraine, abnormal uterine bleeding, or breast cancer.

Drug-Drug Interactions Checker List:

  • GRISEOFULVIN
  • RIFAMPICIN
  • PHENYTOIN
  • RITONAVIR
  • NELFINAVIR
  • LAMOTRIGINE
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended not to consume alcohol along with CYPROTERONE+ETHINYLESTRADIOL to avoid unpleasant side-effects.

    • Safety Warning

      Pregnancy

      unsafe

      CYPROTERONE+ETHINYLESTRADIOL also acts as a contraceptive, so it should not be taken if you are planning to get pregnant or are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      CYPROTERONE+ETHINYLESTRADIOL should be used with caution if using it for PCOS. Other forms of contraception should be used instead of CYPROTERONE+ETHINYLESTRADIOL if you are breastfeeding,

    • Safety Warning

      Driving

      safe if prescribed

      CYPROTERONE+ETHINYLESTRADIOL is not known to affect driving ability.

    • Safety Warning

      Liver

      caution

      CYPROTERONE+ETHINYLESTRADIOL to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      CYPROTERONE+ETHINYLESTRADIOL to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      caution

      CYPROTERONE+ETHINYLESTRADIOL is not recommended for children. Safety and efficacy of CYPROTERONE+ETHINYLESTRADIOL are established in women of reproductive age. Please seek medical advice.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
    • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
    • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
    • Do regular exercise to maintain weight fluctuations caused due to CYPROTERONE+ETHINYLESTRADIOL.
    • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
    • Try to include heart-healthy omega-3 fatty acid-containing food drinks, plenty of fluids, and fruits in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
    • In overweight women, the symptoms of PCOS and the overall risk of developing long-term health problems from PCOS can be greatly reduced by losing excess weight.

    Special Advise

    • Discontinue using any birth control pills, CYPROTERONE+ETHINYLESTRADIOL also acts as a contraceptive.
    • CYPROTERONE+ETHINYLESTRADIOL may cause a patchy, darkening of the skin on the face (melasma). Sunlight may intensify this darkening, and you may need to avoid prolonged sun exposure and sunlamps.

    Patients Concern

    Disease/Condition Glossary

    PCOS: Polycystic ovary syndrome (PCOS) is a common condition, which affects how women's ovaries work. It is characterized by irregular and painful periods, excess androgen in the blood (leading to excessive facial hair and acne), and polycystic ovaries (ovaries become enlarge and the egg become surrounded by fluid-filled sacs).

    Contraception: It is a procedure that aims to prevent pregnancy. A woman can only get pregnant if a man sperm fertilizes her egg. Contraception aims to prevent this from happening by keeping egg and sperm apart by stopping egg production or not letting the uterus wall become thick. As a result, no fertilization takes place, so contraception is a safe method for family planning.

    FAQs

    CYPROTERONE+ETHINYLESTRADIOL is a combination of two hormonal drugs, ethinylestradiol, and cyproterone. Cyproterone works by blocking a male hormone named androgen overproduction in the ovaries and reducing unwanted facial hair growth and acne. Ethinylestradiol, on the other hand, acts as an enhancer. It enhances the effect of cyproterone by reducing the amount of androgens in the blood. Collectively, they both effectively treat the symptoms of PCOS.

    No, CYPROTERONE+ETHINYLESTRADIOL does not protect against sexually transmitted disease. It is an oral form of contraception that does not protect against STDs. So, use some other form of contraception to avoid transmission.

    While taking CYPROTERONE+ETHINYLESTRADIOL, do not smoke and use a condom to avoid any sexually transmitted disease from your partner. Also, do not take St.Wort plant (a natural remedy to treat depression).

    Yes, CYPROTERONE+ETHINYLESTRADIOL is known to cause weight gain. So, to avoid weight gain, do regular exercise, and eat home-cooked food.

    If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule. please wear a condom for 2 days while you If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule. Use other protective methods as advised by your doctor during sexual intercourse to avoid unwanted pregnancy.

    Available Medicines for

    ETHINYLESTRADIOL+CYPROTERONE

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