Dabigatran Etexilate Mesilate
About
Dabigatran Etexilate Mesilate belongs to a class of drugs known as anticoagulants or blood thinners. Dabigatran Etexilate Mesilate is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.
Dabigatran Etexilate Mesilate contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabigatran Etexilate Mesilate preventing blood clot formation in the body.
Take Dabigatran Etexilate Mesilate as prescribed by your doctor. You are advised to take Dabigatran Etexilate Mesilate for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Dabigatran Etexilate Mesilate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Dabigatran Etexilate Mesilate or any other medicines, please tell your doctor. Dabigatran Etexilate Mesilate should not be taken in the conditions like bleeding disorder, or kidney disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Dabigatran Etexilate Mesilate. Dabigatran Etexilate Mesilate should not be used for children below 18 years of age. Dabigatran Etexilate Mesilate has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Dabigatran Etexilate Mesilate as it may increase the risk of bleeding.
Uses of Dabigatran Etexilate Mesilate
Medicinal Benefits
Dabigatran Etexilate Mesilate belongs to a class of drugs known as anticoagulants or blood thinners. Dabigatran Etexilate Mesilate is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent blood clots in the heart and prevent heart attacks. Besides this Dabigatran Etexilate Mesilate is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. This Dabigatran Etexilate Mesilate may also be used to prevent the formation of blood clots after hip replacement surgery. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabigatran Etexilate Mesilate prevents blood clot formation in the body.
Directions for Use
Storage
Side Effects of Dabigatran Etexilate Mesilate
- Bleeding
- Stomach pain
- Nausea
- Indigestion
In-Depth Precautions and Warning
Drug Warnings
If you are known to be allergic to Dabigatran Etexilate Mesilate or any other medicines, please tell your doctor. Dabigatran Etexilate Mesilate should not be taken in the conditions like heart disease, bleeding problems, and kidney disease. Do not take Dabigatran Etexilate Mesilate if you have reduced function of the liver, which might cause death. Inform your doctor if you have a serious injury (bone fracture, head injury). People who have any spinal surgery are more likely to have bleeding problems around the spine when already on this Dabigatran Etexilate Mesilate. This bleeding infrequently occurs but can lead to not moving the body (paralysis) prolonged-term or paralysis that will not go away. Dabigatran Etexilate Mesilate should not be taken if you are older than 75 years. Before taking Dabigatran Etexilate Mesilate inform your doctor if you have a surgery in the past month. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Dabigatran Etexilate Mesilate. Dabigatran Etexilate Mesilate should not be used for children below 18 years of age. Dabigatran Etexilate Mesilate has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Dabigatran Etexilate Mesilate as it may increase the risk of bleeding.
Drug Interactions
Drug-Drug Interaction: Dabigatran Etexilate Mesilate may have interaction with other blood thinners (warfarin, phenprocoumon, heparin, acenocoumarol, clopidogrel, ticagrelor, prasugrel, acetylsalicylic acid, rivaroxaban). antifungal medicines (ketoconazole, itraconazole), medicines for heart disease (amiodarone, dronedarone, quinidine, verapamil), pain killers (acetylsalicylic acid, ibuprofen, diclofenac), antibiotics (rifampicin, clarithromycin), antiviral/HIV medicines (ritonavir), medicines for fit disorder/epilepsy (carbamazepine, phenytoin).
Drug-Food Interaction: Dabigatran Etexilate Mesilate may interact with Dabigatran Etexilate Mesilate may interact with cranberry juice, noni juice, grapefruit juice, pomegranate juice, and green tea. Avoid foods rich in vitamin K such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and brussels sprouts as they may affect the activity of Dabigatran Etexilate Mesilate. Also, avoid alcohol intake as it may increase the risk of bleeding.
Drug-Disease Interaction: Dabigatran Etexilate Mesilate should not be used in patients with a bleeding disorder, heart disease, and kidney disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid alcohol consumption with Dabigatran Etexilate Mesilate as it may increase the risk of bleeding.
Pregnancy
cautionDabigatran Etexilate Mesilate is a Category C pregnancy drug as the effect of Dabigatran Etexilate Mesilate is unknown on the mother and the unborn baby. Avoid the use of Dabigatran Etexilate Mesilate if you are pregnant and inform your doctor.
Breast Feeding
unsafeDabigatran Etexilate Mesilate should not be used while taking Dabigatran Etexilate Mesilate. Inform your doctor if you are a breastfeeding mother.
Driving
safe if prescribedDabigatran Etexilate Mesilate usually does not affect your ability to drive or operate machinery.
Liver
cautionTake Dabigatran Etexilate Mesilate with caution, especially if you have a history of Liver diseases/conditions. Dabigatran Etexilate Mesilate may increase the chances of mild liver injury. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Dabigatran Etexilate Mesilate with caution, especially if you have a history of Kidney diseases/conditions, as this Dabigatran Etexilate Mesilate may cause side effects. The dose may be adjusted by your doctor as required.
Children
unsafeDabigatran Etexilate Mesilate should not be used for children below 18 years as it is not approved for children.
Habit Forming
Diet & Lifestyle Advise
- Avoid making any changes in your diet without first talking to your doctor.
- Opt for high vitamin K foods (liver, leafy green vegetables, or vegetable oils) as Dabigatran Etexilate Mesilate may lower Vitamin K in your body.
- Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Dabigatran Etexilate Mesilate and lead to unwanted side effects. Hence try to avoid these juices while taking Dabigatran Etexilate Mesilate.
- Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.
Special Advise
- Care should be taken to prevent any injury during shaving, playing any sports, or any risky activity, as Dabigatran Etexilate Mesilate may increase the chance of bleeding.
Patients Concern
Disease/Condition Glossary
Stroke (blood clots in the brain): It occurs when the supply of blood to part of your brain is stopped or reduced. Thereby it is preventing brain tissue from getting nutrients and oxygen. Brain cells start to die in minutes.
Deep vein thrombosis (blood clots in the legs): It is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling.
Pulmonary embolism (blood clots in the lung): It is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.
Heart attack: A heart attack means the death of heart tissue due to a shortage of blood supply to the heart muscles. This can occur when there is an accumulation of cholesterol or fat narrowing the heart's major veins or when other substances like a blood clots are blocking the flow of blood. This can destroy or damage a part of the muscle of the heart permanently.
FAQs
People experiencing any uncommon bleeding or people allergic to Dabigatran Etexilate Mesilate should not take Dabigatran Etexilate Mesilate. People with artificial heart valves should also prevent Dabigatran Etexilate Mesilate. Dabigatran Etexilate Mesilate should not take those patients who have bleeding problems and heart disease. The use of this Dabigatran Etexilate Mesilate is not suggested in patients with serious kidney disease.
As compared to other blood thinner medicines, Dabigatran Etexilate Mesilate does not normally cause hair loss. Though, there do exist some unusual reports of hair loss related to Dabigatran Etexilate Mesilate. Inform your doctor if you observe hair loss while taking Dabigatran Etexilate Mesilate.
Yes, Dabigatran Etexilate Mesilate increases the risk of bleeding. Always be cautious while doing activities that may lead to an injury or bleeding. Inform your doctor immediately if you notice any abnormal staining or bleeding.
Dabigatran Etexilate Mesilate works by blocking a substance (a protein known as thrombin) in the blood and preventing blood clot formation. Therefore, Dabigatran Etexilate Mesilate preventing blood clot formation in the body.
Unlike other blood thinners, Dabigatran Etexilate Mesilate generally does not affect the functioning of the liver. But long-term use of Dabigatran Etexilate Mesilate may raise the chances of mild liver injury in patients with a high level of liver enzymes. However, the complete chances of developing any such problem are lesser than other blood thinners. It is advisable to you that before starting this Dabigatran Etexilate Mesilate inform your doctor if you have a history of liver disease.
