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Desloratadine+montelukast

About

Desloratadine+montelukast belongs to the class of medications ‘antiallergic’ used in the treatment of allergic rhinitis. Allergic rhinitis (hay fever) is an allergic response to certain foods or pollen, pet dander, or other allergens.  Allergic condition varies from person to person. It is typically characterized by allergic symptoms such as a runny nose, sneezing, red, watery, itchy, and swollen eyes.

Desloratadine+montelukast is a combination of two medicines: Desloratadine and Montelukast. Desloratadine is an antihistamine and acts by blocking histamine's action (chemicals causing allergic symptoms) and reducing the allergic reaction. It provides quick relief from allergic symptoms. Montelukast is a leukotriene antagonist, which blocks a chemical messenger (leukotriene) and reduces inflammation and swelling in the nose.

You should take this medicine as prescribed by your doctor. The common side-effects of Desloratadine+montelukast are abdominal pain, headache, fatigue, and dry mouth. These side-effects usually go away without any medical treatment. However, if any of these side-effects persist or worsen, consult a doctor immediately.

Do not take Desloratadine+montelukast if you are allergic to Desloratadine, Montelukast, or any other ingredients present in it. Before taking Desloratadine+montelukast, inform your doctor about all the allergies you have, if any. Desloratadine+montelukast is not recommended in patients who have medical or family history of seizures, kidney failure, and phenylketonuria (an inherited disease that causes a build-up of amino acid phenylalanine in the body). Desloratadine+montelukast is not recommended for use in children under 12 years of age. Inform your doctor if you are pregnant or breastfeeding.

Uses of Desloratadine+montelukast

Allergic rhinitis

Medicinal Benefits

Desloratadine+montelukast is a combination of two medicines: Desloratadine and Montelukast. Desloratadine is an antihistamine and acts by blocking histamine's action (chemicals causing allergic symptoms) and reducing the allergic reaction. It provides quick relief from allergic symptoms. Montelukast is a leukotriene antagonist, which blocks a chemical messenger (leukotriene) and reduces inflammation and swelling in the nose. Together, Desloratadine+montelukast improves allergic symptoms such as sneezing, runny nose, coughing, watery eyes, etc. 

Directions for Use

Desloratadine+montelukast should be swallowed as a whole with a glass of water. Do not break, chew, or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Desloratadine+montelukast

  • Abdominal pain
  • Headache
  • Fatigue
  • Dry mouth
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Nausea
  • Vomition
  • Fatigue
  • Irritability

In-Depth Precautions and Warning

Drug Warnings

If you notice any behavioral changes while taking Desloratadine+montelukast, inform your doctor immediately. If you are supposed to undergo skin testing, the doctor might advise you to stop taking Desloratadine+montelukast 72 hours before the test as it decreases response to skin prick test. Do not stop taking Desloratadine+montelukast abruptly even if you feel better, as it may cause withdrawal symptoms such as itching, burning sensations, or runny nose.

Drug Interactions

Drug-Drug Interactions: Desloratadine+montelukast may interact with medications used to treat fits (phenobarbital and phenytoin), an antidepressant (fluoxetine), antacid (cimetidine), pain killer (aspirin), nonsteroidal anti-inflammatory drugs (NSAIDs), antifungal medication (ketoconazole), antibiotics (azithromycin and erythromycin), a medicine used to treat tuberculosis (rifampicin), and medicine used to high cholesterol (gemfibrozil).

Drug-Food Interactions: Avoid grapefruit or grapefruit juice while taking Desloratadine+montelukast. 

Drug-Disease Interactions: Desloratadine+montelukast should be used with caution in patients with seizures, kidney diseases, and phenylketonuria (an inherited disease that causes a build-up of amino acid phenylalanine in the body).

Drug-Drug Interactions Checker List:

  • PHENOBARBITAL
  • PHENYTOIN
  • FLUOXETINE
  • CIMETIDINE
  • KETOCONAZOLE
  • AZITHROMYCIN
  • ERYTHROMYCIN
  • RIFAMPICIN
  • GEMFIBROZIL
  • ASPIRIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol consumption may worsen your health condition and also interfere with the activity of Desloratadine+montelukast. So, do not consume alcohol while taking Desloratadine+montelukast.

    • Safety Warning

      Pregnancy

      unsafe

      Desloratadine+montelukast is a category C medicine. It may cause toxic effects to the fetus. So, it should be used in pregnant women only if needed by doing a benefit/risk assessment.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      Desloratadine+montelukast can be safely used in breastfeeding mothers when prescribed.

    • Safety Warning

      Driving

      caution

      Desloratadine+montelukast may cause drowsiness. So, do not drive or operate heavy machinery if you feel sleepy.

    • Safety Warning

      Liver

      caution

      Desloratadine+montelukast should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Desloratadine+montelukast should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      Desloratadine+montelukast is not recommended for use in children under 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Stay hydrated as it is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate runny nose and sneezing.
    • Avoid stress as the immune system is affected by stress and raises the risk of being sick. An individual can exercise regularly, meditate, do deep breathing, and try progressive muscle relaxation techniques to relieve stress.
    • Avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc., and also certain food items are known to cause allergies to you.
    • Maintain personal hygiene and keep your surroundings clean.

    Special Advise

    • Stop taking Desloratadine+montelukast and inform your doctor or the person before undergoing any tests.

    Patients Concern

    Disease/Condition Glossary

    Allergic rhinitis: It is also called hay fever. It occurs when the immune system responds to foreign elements that are typically not harmful to your body. These foreign elements are known as ‘allergens’ and examples may include pollen, pet dander, and dust mites, etc. Symptoms include itching, watery eyes, swelling around the eyes, runny nose, and sneezing. It is usually identified by performing a skin prick test and allergen-specific immunoglobulin (IgE) antibody test. 

    FAQs

    Desloratadine+montelukast is a combination of two medicines: Desloratadine and Montelukast. Desloratadine is an antihistamine and acts by blocking the action of histamines (chemical substances) that cause allergic symptoms. Montelukast is a leukotriene antagonist, which blocks a chemical messenger (leukotriene) and reduces inflammation and swelling in the nose. Together, Desloratadine+montelukast It provides quick relief from allergic symptoms such as sneezing, runny nose, coughing, watery eyes, etc. 

    Desloratadine+montelukast can be safely taken daily until your allergic symptoms subside and as long as your doctor has advised you to take it.

    The common side-effects of Desloratadine+montelukast are abdominal pain, headache, fatigue, and dry mouth. These side-effects are usually mild and go away without any treatment.

    Desloratadine+montelukast can be safely used in patients with diabetes. However, always consult your doctor before taking Desloratadine+montelukast to discuss the possible risks associated with this medicine.

    Desloratadine+montelukast can improve symptoms in patients with seasonal allergic asthma. However, always consult your doctor before taking Desloratadine+montelukast to discuss the possible risks associated with this medicine.

    Available Medicines for

    Desloratadine+montelukast

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