Dexrabeprazole
About
aDexrabeprazole belongs to a class of drugs called 'proton pump inhibitors' used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.
Dexrabeprazole contains 'Dexrabeprazole' that works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, Dexrabeprazole reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux.
Take Dexrabeprazole as prescribed by your doctor. You are advised to take Dexrabeprazole for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, nausea, vomiting, headache, dizziness, stomach pain or constipation. Most of these side effects of Dexrabeprazole do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Dexrabeprazole or any other medicines, please tell your doctor. Dexrabeprazole is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking Dexrabeprazole. Drive only if you are alert as Dexrabeprazole may cause drowsiness. Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby increasing acidity and heartburn. Inform your doctor if you have any risk factors for reduced vitamin B12 as Dexrabeprazole may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to sun or pain in joints, inform your doctor.
Uses of Dexrabeprazole
Medicinal Benefits
Dexrabeprazole contains Dexrabeprazole used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Dexrabeprazole blocks the action of proton pumps that are involved in producing stomach acid. Thereby, Dexrabeprazole reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux. Also, Dexrabeprazole may be used in combination with clarithromycin and amoxicillin (antibiotics) to eradicate Helicobacter pylori (a type of bacteria) from the stomach in patients with peptic ulcers.
Directions for Use
Storage
Side Effects of Dexrabeprazole
- Diarrhoea
- Nausea
- Vomiting
- Headache
- Dizziness
- Stomach pain
- Constipation
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Dexrabeprazole or any other medicines, please tell your doctor. Dexrabeprazole is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking Dexrabeprazole. If you have a stomach tumor, liver problems, low magnesium levels in the blood, osteoporosis (weak and brittle bones), or lupus (an autoimmune disorder), inform your doctor before taking Dexrabeprazole. Inform your doctor if you have any risk factors for reduced vitamin B12 as Dexrabeprazole may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to sun or pain in joints, inform your doctor. If you are taking Dexrabeprazole for more than 1 year, it may increase the risk of fracture of the spine, hip, or wrist. Drive only if you are alert as Dexrabeprazole may cause drowsiness. Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby increasing acidity and heartburn. Dexrabeprazole may decrease magnesium levels in the blood, especially if taken for more than 3 months. Therefore, regular blood tests are recommended to monitor magnesium levels. If you experience bloody or watery diarrhea with symptoms such as stomach pain, fever, or tenderness, contact your doctor immediately.
Drug Interactions
Drug-Drug Interaction: Dexrabeprazole may interact with anti-HIV drug (atazanavir), antifungals (ketoconazole, itraconazole), anticancer drug (methotrexate), heart-related medicine (digoxin), blood thinner (warfarin).
Drug-Food Interaction: Dexrabeprazole may interact with St. John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption as alcohol intake leads to increased production of stomach acid, thereby irritating the stomach lining and worsening the symptoms.
Drug-Disease Interaction: If you have a stomach tumor, liver problems, low magnesium levels in the blood, osteoporosis (weak and brittle bones), or lupus (an autoimmune disorder), inform your doctor before taking Dexrabeprazole.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption as it may lead to increased production of stomach acid, thereby irritates the stomach lining and worsen the symptoms.
Pregnancy
cautionDexrabeprazole is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.
Breast Feeding
unsafeDexrabeprazole is usually contraindicated in breastfeeding mothers. Therefore, please consult a doctor before taking Dexrabeprazole if you are breastfeeding.
Driving
cautionDexrabeprazole may cause drowsiness in some people. Therefore, avoid driving or operating machinery if you feel drowsy after taking Dexrabeprazole.
Liver
cautionTake Dexrabeprazole with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Dexrabeprazole with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeDexrabeprazole is not recommended for children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Maintain a healthy weight by regular exercising.
- Avoid lying down after eating as it causes acid reflux.
- Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
- Practice relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
- Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Special Advise
- Regular blood tests are recommended while taking Dexrabeprazole to monitor magnesium levels in the blood.
- Dexrabeprazole may cause some abnormal liver enzyme and blood values. These changes are temporary and may return to normal after treatment with Dexrabeprazole is discontinued.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste in the mouth, and difficulty swallowing.
Peptic ulcers: These are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
Zollinger-Ellison syndrome: It is characterized by the formation of tumors in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.
FAQs
Dexrabeprazole contains Dexrabeprazole that works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, Dexrabeprazole reduces the amount of acid produced by stomach and prevents excess acid flowing back into foodpipe. Thus, provides relief from heartburn symptoms related to acid reflux.
Dexrabeprazole may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Dexrabeprazole to prevent dehydration.
Dexrabeprazole may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, tiredness, fits, increased heart rate or dizziness while taking Dexrabeprazole, please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking Dexrabeprazole.
You are not recommended to take Dexrabeprazole with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking Dexrabeprazole with other medicines.
Dexrabeprazole should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if Dexrabeprazole is taken for more than 1 year as it increases the risk of fracture of spine, hip or wrist. Therefore, inform your doctor if have osteoporosis or if you are taking any steroids which may increase the risk of osteoporosis.
Dexrabeprazole may reduce the absorption of vitamin B12 and lead to its deficiency if used for more than 3 years. Therefore, inform your doctor if you have any risk factors for reduced vitamin B12 before taking Dexrabeprazole.
