Dextromethorphan+phenylpropanolamine+menthol+triprolidine
About
Dextromethorphan+phenylpropanolamine+menthol+triprolidine is a combination of medications primarily used to treat dry cough. Additionally, Dextromethorphan+phenylpropanolamine+menthol+triprolidine is also used to treat allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.
Dextromethorphan+phenylpropanolamine+menthol+triprolidine contains Dextromethorphan (cough suppressant), Triprolidine (antihistamine), Phenylpropanolamine (decongestant) and Menthol (cooling/soothing agent). Dextromethorphan belongs to the class of cough suppressants that block the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylpropanolamine is a decongestant that works by contracting and narrowing the small blood vessels of nasal passages and airways, relieving congestion or stuffiness in the nose. Menthol is an additive that acts as a cooling agent that relieves minor irritation in the throat.
Take Dextromethorphan+phenylpropanolamine+menthol+triprolidine as prescribed by your doctor. Your doctor will recommend how often you take Dextromethorphan+phenylpropanolamine+menthol+triprolidine based on your medical condition. Some people may experience nausea, vomiting, drowsiness, stomach upset, dizziness, difficulty sleeping, nervousness or excitation. Most of these side effects of Dextromethorphan+phenylpropanolamine+menthol+triprolidine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Dextromethorphan+phenylpropanolamine+menthol+triprolidine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Dextromethorphan+phenylpropanolamine+menthol+triprolidine. Dextromethorphan+phenylpropanolamine+menthol+triprolidine should be used with caution in children. Avoid using Dextromethorphan+phenylpropanolamine+menthol+triprolidine if you have taken medicines for Parkinson's disease or depression, such as phenelzine, selegiline, rasagiline, isocarboxazid, and tranylcypromine in the past 14 days. You are advised to avoid or limit caffeine intake with Dextromethorphan+phenylpropanolamine+menthol+triprolidine as it may increase the adverse effects. If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus or cough caused by smoking, inform your doctor before taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine.
Uses of Dextromethorphan+phenylpropanolamine+menthol+triprolidine
Medicinal Benefits
Dextromethorphan+phenylpropanolamine+menthol+triprolidine is a combination medication primarily used to treat dry cough. It is also used to treat allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Dextromethorphan helps by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Triprolidine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylpropanolamine helps in contracting and narrowing the small blood vessels of nasal passages and airways, providing relief from congestion or stuffiness in the nose. Menthol produces a sensation of coolness and helps to relieve minor throat irritation.
Directions for Use
Storage
Side Effects of Dextromethorphan+phenylpropanolamine+menthol+triprolidine
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Drowsiness
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Dizziness
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Stomach upset
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Difficulty in sleeping
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Nervousness
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Excitability
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Dextromethorphan+phenylpropanolamine+menthol+triprolidine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Dextromethorphan+phenylpropanolamine+menthol+triprolidine. Dextromethorphan+phenylpropanolamine+menthol+triprolidine should be used with caution in children. Avoid using Dextromethorphan+phenylpropanolamine+menthol+triprolidine if you have taken medicines for Parkinson’s disease or antidepressants like phenelzine, selegiline, rasagiline, isocarboxazid and tranylcypromine the past 14 days. You are advised to avoid caffeine intake with Dextromethorphan+phenylpropanolamine+menthol+triprolidine as it may increase the risk or severity of adverse effects. If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus or cough caused by smoking, inform your doctor before taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine. Drinking grapefruit juice or eating grapefruit can lead to excessive drug accumulation with increased and prolonged effects, so avoid taking it while taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine.
Drug Interactions
Drug-Drug Interaction: Dextromethorphan+phenylpropanolamine+menthol+triprolidine may have interaction with anti-allergic drugs (diphenhydramine, chlorpheniramine, promethazine), narcotic analgesics (hydrocodone, codeine, morphine), central nervous system stimulants (methylphenidate), antidepressants (duloxetine, sertraline, escitalopram), bronchodilators (tiotropium), medicines used to treat irregular heartbeats (quinidine), anticonvulsants (pregabalin), antianxiety drug (alprazolam), antipsychotics (quetiapine).
Drug-Food Interaction: Dextromethorphan+phenylpropanolamine+menthol+triprolidine is known to interact with chocolate and caffeine-containing foods such as cocoa beans and tea leaves, alcohol, grapefruit juice or eating grapefruit. So, avoid intake of these along with Dextromethorphan+phenylpropanolamine+menthol+triprolidine.
Drug-Disease Interaction: Dextromethorphan+phenylpropanolamine+menthol+triprolidine is known to interact in patients with asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus or cough caused by smoking.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Dextromethorphan+phenylpropanolamine+menthol+triprolidine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Dextromethorphan+phenylpropanolamine+menthol+triprolidine.
Pregnancy
cautionThe safety of Dextromethorphan+phenylpropanolamine+menthol+triprolidine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionIt is unknown whether Dextromethorphan+phenylpropanolamine+menthol+triprolidine is excreted in human milk. Dextromethorphan+phenylpropanolamine+menthol+triprolidine is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.
Driving
unsafeDextromethorphan+phenylpropanolamine+menthol+triprolidine may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine.
Liver
cautionTake Dextromethorphan+phenylpropanolamine+menthol+triprolidine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Dextromethorphan+phenylpropanolamine+menthol+triprolidine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionDextromethorphan+phenylpropanolamine+menthol+triprolidine should be used with caution in children below 12 years. Dose adjustments may be necessary.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
- Drink plenty of fluids to avoid dry throat while you cough and loosen mucus.
- Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.
Special Advise
- It is advised to stop the use of Dextromethorphan+phenylpropanolamine+menthol+triprolidine if your cough persists for more than 1 week and it reoccurs or is accompanied by hay fever, skin rash or persistent fever. In such cases, consult a doctor immediately.
- Avoid using Dextromethorphan+phenylpropanolamine+menthol+triprolidine if you have taken medicines for Parkinson’s disease or antidepressants like phenelzine, selegiline, rasagiline, isocarboxazid and tranylcypromine in the past 14 days.
Patients Concern
Disease/Condition Glossary
Cough: Also known as tussis, it is a voluntary or involuntary act and the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings sputum (phlegm, mucus and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.
Allergies: These occur when foreign elements are known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat and watery eyes. Allergies generally occur due to chemicals, air pollution, pet dander, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Dextromethorphan+phenylpropanolamine+menthol+triprolidine is a combination of medications primarily used to treat dry cough. Dextromethorphan blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Triprolidine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylpropanolamine works by contracting and narrowing the small blood vessels of nasal passages and airways, providing relief from congestion or stuffiness in the nose. Menthol produces a sensation of coolness and helps to relieve minor throat irritation. Collectively, all four help to treat dry cough.
Dextromethorphan+phenylpropanolamine+menthol+triprolidine may be used to provide relief from allergic symptoms such as sneezing, runny/stuffy nose, throat irritation or watery eyes. Dextromethorphan+phenylpropanolamine+menthol+triprolidine contains Triprolidine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
You are not recommended to take Dextromethorphan+phenylpropanolamine+menthol+triprolidine with duloxetine (antidepressant) as it may lead to a severe condition called ‘serotonin syndrome’ and symptoms like blurred vision, stomach cramps, diarrhea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine with other medicines.
No, you are not recommended to stop taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine without consulting your doctor, as it may worsen the cough or cause recurring symptoms. Therefore, take Dextromethorphan+phenylpropanolamine+menthol+triprolidine for as long as your doctor has prescribed it, and if you experience any difficulty while taking Dextromethorphan+phenylpropanolamine+menthol+triprolidine, please consult your doctor.
It is advised to take plenty of fluids when you have a cough or cold as it helps to loosen up mucus in the airway. It also helps to lubricate the throat and reduce throat irritation.
Dextromethorphan+phenylpropanolamine+menthol+triprolidine should not be given to treat cough associated with smoking or lower respiratory tract infections such as bronchitis (inflammation of the bronchi), asthma, chronic obstructive pulmonary disease (COPD) and pneumonia.
The mucus starts accumulating at the back of the throat when you lie down and trigger a cough. So, it is advised to incline the head of your bed and use a humidifier while sleeping to reduce cough.
Available Medicines for
Dextromethorphan+phenylpropanolamine+menthol+triprolidine