Dextromethorphan+triprolidine+phenylephrine
About
Dextromethorphan+triprolidine+phenylephrine is a combination of medications primarily used to treat dry cough. Additionally, Dextromethorphan+triprolidine+phenylephrine is also used to treat allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.
Dextromethorphan+triprolidine+phenylephrine is a combination of three drugs, namely: Dextromethorphan (cough suppressant), Triprolidine (antihistamine), and Phenylephrine (decongestant). Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that works by contracting and narrowing the small blood vessels of nasal passage and airways providing relief from congestion or stuffiness in the nose.
Take Dextromethorphan+triprolidine+phenylephrine as prescribed by your doctor. Your doctor will recommend how often you take Dextromethorphan+triprolidine+phenylephrine based on your medical condition. Some people may experience nausea, vomiting, drowsiness, stomach upset, dizziness, difficulty in sleeping, nervousness, or excitation. Most of these side effects of Dextromethorphan+triprolidine+phenylephrine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Dextromethorphan+triprolidine+phenylephrine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Dextromethorphan+triprolidine+phenylephrine. Dextromethorphan+triprolidine+phenylephrine should be used with caution in children. Avoid using Dextromethorphan+triprolidine+phenylephrine if you have taken medicines for Parkinson’s disease or depression such as phenelzine, selegiline, rasagiline, isocarboxazid, and tranylcypromine for the past 14 days. You are advised to avoid or limit caffeine intake with Dextromethorphan+triprolidine+phenylephrine as it may increase the adverse effects. If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus, or cough caused by smoking inform your doctor before taking Dextromethorphan+triprolidine+phenylephrine.
Uses of Dextromethorphan+triprolidine+phenylephrine
Medicinal Benefits
Dextromethorphan+triprolidine+phenylephrine is a combination of three drugs, namely: Dextromethorphan, Triprolidine and Phenylephrine. Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough, which decreases the urge to cough. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions and provides relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stuffiness. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels of nasal passage and airways providing relief from congestion or stuffiness in the nose.
Directions for Use
Storage
Side Effects of Dextromethorphan+triprolidine+phenylephrine
- Drowsiness
- Dizziness
- Stomach upset
- Difficulty in sleeping
- Nervousness and excitable
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Dextromethorphan+triprolidine+phenylephrine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Dextromethorphan+triprolidine+phenylephrine. Dextromethorphan+triprolidine+phenylephrine should be used with caution in children. Avoid using Dextromethorphan+triprolidine+phenylephrine if you have taken medicines for Parkinson’s disease or antidepressants like phenelzine, selegiline, rasagiline, isocarboxazid, and tranylcypromine the past 14 days. You are advised to avoid caffeine intake with Dextromethorphan+triprolidine+phenylephrine as it may increase the risk of severity of adverse effects. If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus, or cough caused by smoking, inform your doctor before taking Dextromethorphan+triprolidine+phenylephrine. Caution is advised when drinking grapefruit juice or eating grapefruit as it can lead to excessive accumulation of the drug with both increased and prolonged effects.
Drug Interactions
Drug-Drug Interaction: Dextromethorphan+triprolidine+phenylephrine may have interaction with anti-allergic drugs (diphenhydramine, chlorpheniramine, promethazine), narcotic analgesics (hydrocodone, codeine, morphine), central nervous system stimulants (methylphenidate), antidepressants (duloxetine, sertraline, escitalopram), bronchodilators (tiotropium), medicines used to treat irregular heartbeats (quinidine), anticonvulsants (pregabalin), antianxiety drug (alprazolam), antipsychotics (quetiapine).
Drug-Food Interaction: Avoid or limit the intake of chocolate and caffeine-containing foods such as cocoa beans and tea leaves with Dextromethorphan+triprolidine+phenylephrine as they may increase the risk of severity of side effects. Also, avoid consumption of alcohol with Dextromethorphan+triprolidine+phenylephrine as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating. Avoid drinking grapefruit juice or eating grapefruit as it can lead to excessive accumulation of the drug with both increased and prolonged effects.
Drug-Disease Interaction: If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus, or cough caused by smoking, inform your doctor before taking Dextromethorphan+triprolidine+phenylephrine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Dextromethorphan+triprolidine+phenylephrine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Dextromethorphan+triprolidine+phenylephrine.
Pregnancy
cautionThe safety of Dextromethorphan+triprolidine+phenylephrine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionIt is unknown whether Dextromethorphan+triprolidine+phenylephrine is excreted in human milk. Dextromethorphan+triprolidine+phenylephrine is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.
Driving
cautionDextromethorphan+triprolidine+phenylephrine may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Dextromethorphan+triprolidine+phenylephrine.
Liver
cautionTake Dextromethorphan+triprolidine+phenylephrine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
safe if prescribedIf you have any concerns regarding the use of Dextromethorphan+triprolidine+phenylephrine in patients with Kidney problems, please consult a doctor.
Children
cautionDextromethorphan+triprolidine+phenylephrine should be used with caution in children if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
- Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
- Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.
Special Advise
You are recommended to consult a doctor if the cough persists or worsens after 1 week of treatment with Dextromethorphan+triprolidine+phenylephrine.
Patients Concern
Disease/Condition Glossary
Cough: Also known as tussis, is a voluntary or involuntary act and the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.
Allergies: These occur when foreign elements are known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet dander, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Dextromethorphan+triprolidine+phenylephrine contains Dextromethorphan, Triprolidine and Phenylephrine. Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, decreases the urge to cough. Triprolidine is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions and provides relief from symptoms of allergy. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases the mucus production.
Dextromethorphan+triprolidine+phenylephrine may be used to provide relief from allergic symptoms such as sneezing, runny/stuffy nose, throat irritation or watery eyes. Dextromethorphan+triprolidine+phenylephrine contains Triprolidine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Yes, Dextromethorphan+triprolidine+phenylephrine may cause dizziness in some people. It is not necessary for everyone taking Dextromethorphan+triprolidine+phenylephrine to experience this side effect. However, avoid driving or operating heavy machinery if you feel dizzy after taking Dextromethorphan+triprolidine+phenylephrine.
You are recommended to take Dextromethorphan+triprolidine+phenylephrine for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after using Dextromethorphan+triprolidine+phenylephrine, please consult your doctor.
You are not recommended to take Dextromethorphan+triprolidine+phenylephrine with duloxetine (antidepressant) as it may lead to a severe condition called ‘serotonin syndrome’ and symptoms like blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Dextromethorphan+triprolidine+phenylephrine with other medicines.
No, you are not recommended to stop taking Dextromethorphan+triprolidine+phenylephrine without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Dextromethorphan+triprolidine+phenylephrine for as long as your doctor has prescribed it and if you experience any difficulty while taking Dextromethorphan+triprolidine+phenylephrine, please consult your doctor.