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Diethylcarbamazine+guaifenesin+chlorpheniramine

About Diethylcarbamazine+guaifenesin+chlorpheniramine

Diethylcarbamazine+guaifenesin+chlorpheniramine belongs to the class of medicines called 'anti-parasitic' used to treat certain worm or parasitic infections, including Bancroft's filariasis, eosinophilic lung, loiasis, and river blindness. The worms or parasites live inside the human body and receive important nutrients from a person's body and make them sick called parasitic infection. Diethylcarbamazine+guaifenesin+chlorpheniramine does not work against worm infections caused by pinworms or tapeworms.

Diethylcarbamazine+guaifenesin+chlorpheniramine contains Diethylcarbamazine, Chlorpheniramine, and Guaifenesin. Diethylcarbamazine paralyzes the parasitic worms by stopping them from interacting with the host cell, thereby killing it. Chlorpheniramine is an antihistamine that works by reducing allergic symptoms such as eosinophilia (increased number of disease-fighting white blood cells), cough, sneezing, and trouble breathing. Guaifenesin is an expectorant that works by loosening the mucus (phlegm) in the chest and throat, making it easier to cough out. 

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Diethylcarbamazine+guaifenesin+chlorpheniramine are nausea (feeling sick), vomiting (being sick), stomach discomfort, headache, joint pain, tiredness, and drowsiness. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Diethylcarbamazine+guaifenesin+chlorpheniramine if you are allergic to any contents of it. Before taking Diethylcarbamazine+guaifenesin+chlorpheniramine, inform your doctor if you have high blood pressure, heart disease, fits, glaucoma (increased pressure in the eye), enlarged prostate, liver or kidney disease, bronchitis (inflammation of the bronchi), asthma, or any other chronic lung problems. It should not be used in children. It should be used with caution in pregnant and breastfeeding women. Do not consume alcohol while taking this medicine as it may increase the risk of side-effects. Diethylcarbamazine+guaifenesin+chlorpheniramine may cause drowsiness, so do not drive or operate heavy machinery if you feel drowsy.

Uses of Diethylcarbamazine+guaifenesin+chlorpheniramine

Parasitic infections

Medicinal Benefits

Diethylcarbamazine+guaifenesin+chlorpheniramine is used in the treatment of certain worm or parasitic infections. It contains diethylcarbamazine, which can kill parasites. Chlorpheniramine and Guaifenesin help to relieve symptoms of infection. You may start to feel better quickly after using this medicine. However, you should complete the course of therapy to clear up the infection completely. 

Directions for Use

Swallow Diethylcarbamazine+guaifenesin+chlorpheniramine as a whole with a glass of water. Do not chew, crush, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diethylcarbamazine+guaifenesin+chlorpheniramine

  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Stomach discomfort
  • Headache
  • Joint pain
  • Tiredness
  • Drowsiness

Drug Warnings

Do not take Diethylcarbamazine+guaifenesin+chlorpheniramine if you have taken monoamine oxidase inhibitors (MAOI), a type of antidepressant in the past 14 days. Diethylcarbamazine+guaifenesin+chlorpheniramine may cause loss of vision or night blindness when used for prolonged periods. So, inform your doctor immediately if you notice any changes in vision. It should be used with caution in patients with asthma. Do not take this medicine if you are wheezing or having an asthma attack.

Drug Interactions

Drug-Drug Interactions: Diethylcarbamazine+guaifenesin+chlorpheniramine may interact with monoamine oxidase inhibitors (selegiline, rasagiline, and tranylcypromine).

Drug-Food Interactions: Do not consume alcohol as it may cause excessive drowsiness.

Drug-Disease Interactions: Diethylcarbamazine+guaifenesin+chlorpheniramine should be used with caution in patients with high blood pressure, heart disease, fits, glaucoma (increased pressure in the eye), enlarged prostate, liver or kidney disease, bronchitis (inflammation of the bronchi), asthma, or any other chronic lung problems.

Drug-Drug Interactions Checker List:

  • SELEGILINE
  • RASAGILINE
  • TRANYLCYPROMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Do not consume alcohol while taking this medicine as it may increase the risk of side-effects.

    • Safety Warning

      Pregnancy

      caution

      Diethylcarbamazine+guaifenesin+chlorpheniramine should be used with caution in pregnant women only if the doctor thinks it is clinically needed and when benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Diethylcarbamazine+guaifenesin+chlorpheniramine should be used with caution in breastfeeding women only if the doctor thinks it is clinically needed and benefits outweigh the risks.

    • Safety Warning

      Driving

      unsafe

      Diethylcarbamazine+guaifenesin+chlorpheniramine may cause drowsiness or vision changes, so do not drive or operate heavy machinery if you are not fully alert.

    • Safety Warning

      Liver

      caution

      Diethylcarbamazine+guaifenesin+chlorpheniramine should be used with caution in patients with liver diseases. The dose may have to be adjusted by the doctor as required.

    • Safety Warning

      Kidney

      caution

      Diethylcarbamazine+guaifenesin+chlorpheniramine should be used with caution in patients with kidney diseases. The dose may have to be adjusted by the doctor as required.

    • Safety Warning

      Children

      unsafe

      It is not recommended for use in children below 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Consume a balanced diet, which is high in nutrients and less in refined sugars/processed foods.
    • Fiber is important for the bowel movement, helping cleanse parasites from the body, including more fiber-rich foods in the body like oats.
    • Include pumpkin seeds, garlic, honey, and papaya seeds as antiparasitic foods in your diet.
    • Doctors may recommend a grain-free, sugar-free diet, while others may recommend limiting fruit intake to reduce further dietary sugars, so better talk to your nutritionist.

    Special Advise

    • Your doctor may monitor your condition regularly at follow-up visits to check whether the infection is cleared up completely. In addition, your doctor may advise you to undergo a regular eye examination while using this medicine.  

    Patients Concern

    Disease/Condition Glossary

    Bancroft's filariasis: It is caused by thread-like worms that live inside the lymphatic system of humans. The lymphatic system of the body consists of fluid and is responsible for fighting infections. This disease spreads from one person to person by mosquitoes. Common symptoms include fever, skin exfoliation. And high levels of eosinophils (white blood cells).

    Loiasis: It is also called 'African eye worm', which is an infectious parasitic disease transmitted to humans by the bite of Chrysops deerfly species. A person dealing with this disease may face itchy, non-painful swellings in their body. Sometimes, a person may see worms crawling under their skin or an eye worm.

    River blindness: This is caused by a parasitic worm and is transmitted through repeated bites by black flies near the rivers and streams. If not treated, then it may even cause visual impairment and sometimes blindness.

    Eosinophilic lung: This is a disease related to lung problems in which white blood cells in the body get increased. White blood cells are responsible for fighting allergic reactions and certain infections. Some of these disease symptoms include cough, chest pain, chest tightness, increased mucus, rapid breathing, and bloody mucus.

    FAQs

    Diethylcarbamazine+guaifenesin+chlorpheniramine contains Diethylcarbamazine, Chlorpheniramine, and Guaifenesin. Diethylcarbamazine paralyzes the parasitic worms by stopping them from interacting with the host cell, thereby killing it. Chlorpheniramine is an antihistamine that works by reducing allergic symptoms such as eosinophilia (increased number of disease-fighting white blood cells), cough, sneezing, and trouble breathing. Guaifenesin is an expectorant that works by loosening the mucus (phlegm) in the chest and throat, making it easier to cough out.

    The common side-effects of Diethylcarbamazine+guaifenesin+chlorpheniramine are nausea (feeling sick), vomiting (being sick), stomach discomfort, headache, joint pain, tiredness, and drowsiness. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

    It is not advised to take Diethylcarbamazine+guaifenesin+chlorpheniramine if you have taken monoamine oxidase (MAO) inhibitors (a type of antidepressant) in the past 14 days. So, it is necessary to inform your doctor about all the prescription or non-prescription medicines you are using.

    Diethylcarbamazine+guaifenesin+chlorpheniramine should be used with caution in patients with high blood pressure, heart disease, fits, glaucoma (increased pressure in the eye), enlarged prostate, liver or kidney disease, bronchitis (inflammation of the bronchi), asthma, or any other chronic lung problems.

    Diethylcarbamazine+guaifenesin+chlorpheniramine may cause loss of vision or night blindness on prolonged use. So, inform your doctor if you notice any changes in your vision. In addition, do not drive or operate heavy machinery if your vision is not clear.

    Available Medicines for

    Diethylcarbamazine+guaifenesin+chlorpheniramine

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