Esomeprazole+naproxen

Do not take Esomeprazole+naproxen if you are allergic to Esomeprazole+naproxen. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin), such as naproxen, may increase the risk of heart attack, stroke, and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, are older, are alcoholics, or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems, so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. Esomeprazole+naproxen is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Esomeprazole+naproxen. Esomeprazole+naproxen should not be given to children unless prescribed by a doctor. Do not take any other NSAIDs for pain relief along with Esomeprazole+naproxen unless prescribed. Prolonged proton pump inhibitors like esomeprazole may cause brittle bones, so your doctor may recommend taking Vitamin D and calcium while using Esomeprazole+naproxen. Do not consume alcohol with Esomeprazole+naproxen as it may increase the risk of stomach bleeding or ulcer.

Drug-Drug Interactions: Esomeprazole+naproxen may have interaction with anti-inflammatory medicines (e.g. aspirin, ibuprofen), blood thinners (e.g. warfarin, rivaroxaban), steroids (e.g. prednisolone), diuretic medicines (e.g. furosemide), medicines used to treat heart problems and high blood pressure-lowering medicines (e.g. propranolol, enalapril, losartan, candesartan), antidepressants (e.g. citalopram), and medicine used to treat rheumatoid arthritis (e.g. methotrexate)

Drug-Food Interactions: Esomeprazole+naproxen may interact with alcohol. Therefore, avoid alcohol intake while taking Esomeprazole+naproxen as it may increase the risk of stomach bleeding and drowsiness, and dizziness.

Drug-Disease Interactions: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver, or heart problems, and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever, and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting, and weight loss) should consult a doctor before taking Esomeprazole+naproxen.

• Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
• Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
• Acupuncture, massage and physical therapy may also be helpful.
• Foods containing flavonoids, such as soy, berries, broccoli, grapes and green tea, help reduce inflammation.
• Include high-fibre-containing foods, berries, cherries, leafy green veggies and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut and kimchi contain probiotics that help prevent excess stomach acid production.
• Avoid acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
• Avoid smoking and alcohol consumption.

• If you are elderly, a smoker who had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor, as these conditions may increase the risk of heart problems.
• Your doctor may monitor liver and kidney function if you take Esomeprazole+naproxen for the long-term.
• Individuals at risk for osteoporosis-related fractures should receive adequate calcium and vitamin D intake.
• Esomeprazole in Esomeprazole+naproxen may interfere with specific laboratory tests (including urine test for tetrahydrocannabinol-THC, a blood test to find certain tumours), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using Esomeprazole+naproxen.
• Regular monitoring of vitamin B-12, rarely, esomeprazole in Esomeprazole+naproxen has chased vitamin B-12 deficiency. The risk increases if they take Esomeprazole+naproxen every day for a long time.