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Ethosuximide

About

Ethosuximide belongs to a group of anticonvulsants or anti-epileptic medications primarily used to treat epilepsy/seizures/fits. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

The Ethosuximide contains 'ethosuximide', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures.

Take Ethosuximide as prescribed. Depending on your medical condition, you should take Ethosuximide for as long as your doctor has prescribed it. Sometimes, you may experience certain common side effects, such as nausea, vomiting, hiccup, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Ethosuximide without consulting your doctor to avoid worsening seizures. Inform your doctor if you have had an allergic reaction to Ethosuximide or any ingredients. Keep your doctor informed about your health condition and all the medicines you take before taking Ethosuximide to rule out any side effects. Do not take Ethosuximide if you are pregnant or breastfeeding unless prescribed by the doctor. Ethosuximide to be taken with caution, and the dose may have to be adjusted by your doctor if you have had a history of kidney/liver diseases. Ethosuximide may alter the ability to drive. Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

Uses of Ethosuximide

Epilepsy/seizures/fits

Medicinal Benefits

Ethosuximide belongs to a group of anticonvulsants or anti-epileptic medications primarily used to treat epilepsy/seizures/fits. Ethosuximide contains ‘ethosuximide’, which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures.

Directions for Use

Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Side Effects of Ethosuximide

  • Nausea
  • Vomiting
  • Hiccup
  • Abdominal pain
  • Severe headache
  • Sleep disturbances
  • Lethargy (lack of drive, apathy)
  • Ataxia (movement disorders)
  • Anxiety
  • Loss of appetite
  • Loss of weight
  • Diarrhoea
  • Constipation

In-Depth Precautions and Warning

Drug Warnings

Please do not stop taking Ethosuximide without consulting your doctor to avoid worsening seizures. Inform your doctor if you have had an allergic reaction to Ethosuximide or any ingredients in it. Keep your doctor informed about your health condition and all the medicines you take before taking Ethosuximide to rule out any side effects. Do not take Ethosuximide if you are pregnant or breastfeeding unless prescribed by the doctor. Ethosuximide to be taken with caution, and the dose may have to be adjusted by your doctor if you have had a history of kidney/liver diseases. Ethosuximide may alter the ability to drive. Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Consult your doctor immediately if you experience suicidal tendencies or mood swings.

Drug Interactions

Drug-Drug Interactions: Ethosuximide may have interaction with other anticonvulsants (e.g. brivaracetam, divalproex sodium, perampanel, carbamazepine, oxcarbazepine), benzodiazepines (e.g. clobazam), anti-depression (e.g. paroxetine, duloxetine), antihistamines (diphenhydramine), and opiate analgesics (tramadol). These are not a complete list of interactions. Ask your doctor or pharmacist for more information.

Drug-Food Interactions: Consuming alcohol with Ethosuximide is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.

Drug-Disease Interactions: People affected with bone marrow depression/low blood counts, renal dysfunction, systemic lupus erythematosus (An inflammatory disease caused when the immune system attacks its tissues), depression, and psychosis should consult the doctor before taking Ethosuximide.

Drug-Drug Interactions Checker List:

  • BRIVARACETAM
  • DIVALPROEX SODIUM
  • PERAMPANEL
  • CARBAMAZEPINE
  • OXCARBAZEPINE
  • CLOBAZAM
  • PAROXETINE
  • DULOXETINE
  • DIPHENHYDRAMINE
  • TRAMADOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Consume alcohol along with Ethosuximide is not advisable as it may cause unpleasant side effects or you also may become more sensitive to the effects of alcohol.

    • Safety Warning

      Pregnancy

      caution

      Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor; there is no substantial research yet on using Ethosuximide in breastfeeding/nursing mothers.

    • Safety Warning

      Driving

      caution

      Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

    • Safety Warning

      Liver

      caution

      Ethosuximide to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor. Please consult the doctor.

    • Safety Warning

      Kidney

      caution

      Ethosuximide to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor. Please consult the doctor.

    • Safety Warning

      Children

      caution

      Limited information was available for the use of Ethosuximide in paediatric patients. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Rest well, and get plenty of sleep.
    • Avoid smoking and alcohol consumption.
    • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
    • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
    • Install an alarm or emergency device to get assistance during a seizure attack.

    Patients Concern

    Disease/Condition Glossary

    Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: Generalized and Partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle cramps and spasms. More substantial seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

    FAQs

    Ethosuximide contains ‘ethosuximide’, which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

    No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

    Please do not stop using Ethosuximide without consulting your doctor on your own. Continue using Ethosuximide for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Ethosuximide.

    Ethosuximide is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

    Long-term administration of Ethosuximide may adversely affect fear memory but does not affect spatial learning and memory.

    Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

    Available Medicines for

    Ethosuximide

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