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Etodolac+thiocolchicoside

About

Etodolac+thiocolchicoside belongs to a group of medicines called analgesics used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.
 
Etodolac+thiocolchicoside is a combination of two drugs, namely: Etodolac (NSAID) and Thiocolchicoside (Muscle relaxant). Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helps relieve pain due to muscle spasms.
 
You are advised to take Etodolac+thiocolchicoside for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Etodolac+thiocolchicoside may cause common side effects such as nausea, vomiting, heartburn, stomach pain, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Etodolac+thiocolchicoside may cause drowsiness and dizziness, so drive with caution. Etodolac+thiocolchicoside is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Etodolac+thiocolchicoside as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Etodolac+thiocolchicoside

Osteoarthritis, rheumatoid arthritis, pain and muscle spasms

Medicinal Benefits

Etodolac+thiocolchicoside is a combination of two drugs: Etodolac (Non-Steroidal Anti-Inflammatory Drugs) and Thiocolchicoside (Muscle relaxant). Etodolac+thiocolchicoside is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandins, which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

Directions for Use

Take Etodolac+thiocolchicoside with food to avoid stomach upset. Swallow Etodolac+thiocolchicoside as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Etodolac+thiocolchicoside

  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Indigestion

In-Depth Precautions and Warning

Drug Warnings

Do not take Etodolac+thiocolchicoside if you are allergic to any of its contents; if you have stomach ulcers, bleeding problems, clotting problems, inflammatory bowel disease, severe heart, liver or kidney problems, galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Inform your doctor if you have/had stomach bleeding or ulcers, heart failure, high blood pressure, diabetes, high cholesterol, kidney or liver impairment. Consult your doctor if you are pregnant or breastfeeding. Etodolac+thiocolchicoside may cause drowsiness and dizziness, so drive only if you are alert. Etodolac+thiocolchicoside is not recommended for children as safety has not been established. Stop taking Etodolac+thiocolchicoside and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Etodolac+thiocolchicoside unless prescribed.

Drug Interactions

Drug-Drug Interactions: Etodolac+thiocolchicoside may interact with pain killers (aspirin, ibuprofen, naproxen, diclofenac), anti-depressants (duloxetine, escitalopram), cardiac glycoside (digoxin), anti-hypertensives (metoprolol), blood thinners (warfarin), anti-psychotic (lithium), immunosuppressants (cyclosporine), steroids (mifepristone), quinolone antibiotics, diuretics, and sedative drugs.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have heart failure, fluid retention (oedema), asthma, gastrointestinal ulcer/bleeding, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption, heart, kidney or liver problems.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • DICLOFENAC
  • DULOXETINE
  • ESCITALOPRAM
  • DIGOXIN
  • METOPROLOL
  • WARFARIN
  • LITHIUM
  • CYCLOSPORINE
  • MIFEPRESTONE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Etodolac+thiocolchicoside as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Please consult your doctor if you are breastfeeding; your doctor will decide whether Etodolac+thiocolchicoside can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Etodolac+thiocolchicoside may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Etodolac+thiocolchicoside is not recommended for children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
    • Performing yoga may also help in improving joint flexibility and pain management.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
    • Acupuncture, massage and physical therapy may also be helpful.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Avoid smoking and alcohol consumption.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

    Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

    Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

    Muscle spasms: The sudden involuntary contractions of the muscle can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in moving, and pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms. 

    FAQs

    Etodolac+thiocolchicoside is a combination of two drugs: Etodolac and Thiocolchicoside. Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, 'prostaglandins'. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

    Etodolac+thiocolchicoside is used to reduce and relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Arthritis is tenderness and swelling in the joints.

    Avoid taking Etodolac+thiocolchicoside if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternate medicine.

    Diarrhoea might be a side-effect of Etodolac+thiocolchicoside. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Etodolac+thiocolchicoside contains etodolac, which might make the skin sensitive to sunlight and may result in sunburn. Avoid exposure to sunlight and artificial UV rays such as tanning beds and sunlamps while taking Etodolac+thiocolchicoside. Whenever you step out of the home, try to apply sunscreen.

    Etodolac+thiocolchicoside may increase the risk of fatal heart attack or stroke. If you have any recent heart bypass surgery, do not use Etodolac+thiocolchicoside. Talk to your doctor before taking Etodolac+thiocolchicoside if you have heart problems.

    Available Medicines for

    Etodolac+thiocolchicoside

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