Folic Acid+methylcobalamin+pyridoxine
About
Folic Acid+methylcobalamin+pyridoxine belongs to the class of 'Vitamins', primarily used to treat nutritional deficiencies. It is used to treat and prevent nutritional deficiencies such as vitamin B6 deficiency, folate deficiency and vitamin B12 deficiency. A nutritional deficiency occurs when the body does not absorb or get enough nutrients from food. Folic Acid+methylcobalamin+pyridoxine helps in the growth and development of cells, boosts the immune system, balances vitamin content, metabolism of minerals, and helps maintain a healthy central nervous system.
Folic Acid+methylcobalamin+pyridoxine contains Folic acid, Pyridoxine, and Methylcobalamin. Folic acid is the synthetic form of folate. It helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. It prevents and treats low blood levels of folate (folate deficiency), and high blood levels of an amino acid, homocysteine (hyperhomocysteinemia). Pyridoxine is also known as vitamin B6. It is a water-soluble vitamin involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions, such as cell multiplication, blood formation, and protein synthesis.
Take Folic Acid+methylcobalamin+pyridoxine as advised by the doctor. Sometimes, Folic Acid+methylcobalamin+pyridoxine may have common side effects like nausea, stomach upset, diarrhoea, drowsiness, flushing, and numbness/tingling. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects gradually.
Let your doctor know if you are using any other medicines or herbal products before starting Folic Acid+methylcobalamin+pyridoxine. If you are known to be allergic to Folic Acid+methylcobalamin+pyridoxine or its inactive components, please inform your doctor. Please tell your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food). In such a case, the dosage form may be changed to intravenous administration of individual vitamins for better absorption. If you are a pregnant or breastfeeding mother, please consult your doctor before taking Folic Acid+methylcobalamin+pyridoxine.
Uses of Folic Acid+methylcobalamin+pyridoxine
Medicinal Benefits
Folic Acid+methylcobalamin+pyridoxine is used to treat nutritional deficiencies. It contains Folic acid, Pyridoxine, and Methylcobalamin. Folic acid is the synthetic form of folate, a water-soluble Vitamin B. It helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. It prevents and treats folate deficiency and hyperhomocysteinemia. Pyridoxine (vitamin B6) is a water-soluble vitamin that treats and prevents vitamin B6 deficiency. It is involved in protein, fat, and carbohydrate metabolism and the creation of red blood cells and neurotransmitters. It helps in cognitive development through neurotransmitter biosynthesis and maintains normal homocysteine levels (an amino acid in the blood). Methylcobalamin (Mecobalamin) is a coenzyme form of vitamin B12 and treats Vitamin B12 deficiency. Methylcobalamin regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Folic Acid+methylcobalamin+pyridoxine helps treat nutritional deficiencies.
Directions for Use
Storage
Side Effects of Folic Acid+methylcobalamin+pyridoxine
- Nausea
- Stomach upset
- Diarrhoea
- Drowsiness
- Flushing
- Numbness/tingling
In-Depth Precautions and Warning
Drug Warnings
Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food). This disease may make it hard to absorb B complex vitamins when given orally. Your doctor may advise other dosage forms in such cases. Let your doctor know if you have any blood disorders like pernicious anaemia before starting Folic Acid+methylcobalamin+pyridoxine. Pyridoxine and folic acid in Folic Acid+methylcobalamin+pyridoxine are excreted into the breast milk. Pregnant or breastfeeding women should consult their doctor before taking Folic Acid+methylcobalamin+pyridoxine. Excessive alcohol consumption reduces absorption and increases the elimination of folic acid. Alcohol can also worsen the side effects like drowsiness and stomach upset. Hence, please avoid alcohol while using Folic Acid+methylcobalamin+pyridoxine.
Drug Interactions
Drug-Drug Interactions: Folic Acid+methylcobalamin+pyridoxine may interact with anti-cancer drugs (altretamine, cisplatin, and arsenic trioxide), anti-epileptic medicines (phenytoin, phenobarbital, primidone), antibiotic (chloramphenicol), medicines treating Parkinson's disease (levodopa), drugs used to treat tumours (Fluorouracil), antibiotics (trimethoprim), stomach related drugs (sulfasalazine), and cholesterol-lowering drugs (cholestyramine).
Drug-Food Interactions: Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Alcohol can also worsen the side effects like drowsiness and stomach upset.
Drug-Disease Interactions: Use Folic Acid+methylcobalamin+pyridoxine with medical advice if you have malabsorption syndrome (difficulty absorbing nutrition from food) and allergic reactions to medicines.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionExcessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using Folic Acid+methylcobalamin+pyridoxine.
Pregnancy
cautionFolic Acid+methylcobalamin+pyridoxine should be used during pregnancy only when advised by your doctor. Let your doctor know if you are pregnant or planning to conceive before taking Folic Acid+methylcobalamin+pyridoxine.
Breast Feeding
cautionPyridoxine and Folic acid in Folic Acid+methylcobalamin+pyridoxine are excreted into the breast milk. Please consult your doctor before taking Folic Acid+methylcobalamin+pyridoxine if you are a breastfeeding mother.
Driving
cautionFolic Acid+methylcobalamin+pyridoxine may sometimes make you feel sleepy. Do not drive or operate machinery if you are not mentally alert and focused.
Liver
cautionLet your doctor know if you have any history of liver diseases before taking Folic Acid+methylcobalamin+pyridoxine. Your dosage may be adjusted in case of hepatic impairment.
Kidney
cautionLet your doctor know if you have any history of kidney diseases before taking Folic Acid+methylcobalamin+pyridoxine. Your dosage may be adjusted in case of renal impairment.
Children
consult your doctorYour doctor will recommend the dosage of Folic Acid+methylcobalamin+pyridoxine based on the child's age and weight.
Habit Forming
Diet & Lifestyle Advise
- Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, and salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
- Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid.
- Sprinkle sunflower seeds over your food, vegetables and salads.
- Include fruits like citrus, banana and watermelon in your diet.
- Avoid smoking and alcohol consumption.
- Exercise regularly, and maintain a healthy lifestyle. Avoid excess fatty foods.
Special Advise
- Clinical monitoring of folic acid, vitamins B12 and B6 levels through blood examinations is recommended.
- Let your doctor and the laboratory staff know if you are using Folic Acid+methylcobalamin+pyridoxine since Pyridoxine may interfere with laboratory tests like urine test for urobilinogen.
Patients Concern
Disease/Condition Glossary
Vitamin B6 deficiency: When your body doesn't have adequate levels of a water-soluble vitamin called Pyridoxine or Vitamin B6, this disease is developed. Vitamin B6 deficiency symptoms include fatigue, skin rashes, cracked and sore lips, weak immune system, tiredness and low energy levels, tingling in hands and feet, and fits.
Vitamin B12 deficiency (cobalamin deficiency): When your body doesn't have adequate mineral levels called Vitamin B12, it leads to Vitamin B12 deficiency. Symptoms include fatigue, breathlessness, numbness, poor balance and memory trouble.
Folate deficiency: Folate deficiency occurs when your body won't have enough folate in your diet. Symptoms include fatigue, grey hair, mouth sores, tongue swelling and growth problems.
FAQs
Folic Acid+methylcobalamin+pyridoxine is a vitamin supplement and consists of Folic acid, Pyridoxine (vitamin B6) and Methylcobalamin (vitamin B12). When you lack these vitamins in your body, which cannot be recovered even with the food sources, Folic Acid+methylcobalamin+pyridoxine helps in normalising these deficient levels. Collectively, Folic Acid+methylcobalamin+pyridoxine treats nutritional deficiencies.
Vitamin B6 deficiency occurs when your body lacks adequate Pyridoxine levels. You can overcome this deficiency by including food sources rich in Pyridoxine like milk, eggs, beef, pork, chicken or turkey, fish, peanuts, soya beans, wheat germ, oats and bananas. If your Vitamin B6 levels are still low, your doctor may recommend its supplements.
Vitamin B12 deficiency is caused when you don't have enough Methylcobalamin or Mecobalmin levels in your body. You can include natural Vitamin B12 sources like eggs, beef, liver, chicken, trout, salmon, tuna fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese in your diet for treating the deficiency. If you still have low levels of B12, please consult your doctor for its supplements.
Folate deficiency occurs when your body lacks adequate folic acid/folate levels. You can overcome this deficiency by including food sources rich in folic acid like broccoli, brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid. If your folic acid levels are still low, your doctor may recommend its supplements.
It is important to tell your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food) since it may be hard to absorb vitamins through oral administration. Your doctor may advise other dosage forms in such cases.
Pyridoxine in Folic Acid+methylcobalamin+pyridoxine may interfere with laboratory tests like urine test for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Folic Acid+methylcobalamin+pyridoxine before undergoing any blood and urine examinations.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
