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Furazolidone+metronidazole

About

Furazolidone+metronidazole belongs to a class of medicines known as antibiotics. This is used to treat various infections caused by bacteria, dysentery and diarrhea. A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our bodies. It can target any body part and multiple very quickly. Amoebic dysentery can be caused due to entamoeba histolytica, giardia lamblia or clostridium difficile. Diarrhea is the increase in bowel movement leading to increased and loose motions.

Furazolidone+metronidazole is a combination of two antibiotics that include furazolidone and metronidazole. Furazolidone+metronidazole contains flurazolidone works by interfering with the protein synthesis, a mechanism which is important for survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively they help in treating the disease effectively.

Take Furazolidone+metronidazole as prescribed by your doctor. Your doctor will recommend how often you take Furazolidone+metronidazole based on your medical condition. Some people may experience nausea, dryness in the mouth, headache, metallic taste, and dark yellow to brown discoloration of urine. Most of these side effects of Furazolidone+metronidazole do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Furazolidone+metronidazole should not be taken if you are allergic to Furazolidone+metronidazole or any other contents present in it. It is not advisable to stop taking Furazolidone+metronidazole suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed. Furazolidone+metronidazole should not be taken in the conditions like a history of liver and kidney disease. It is advisable to you do not drive while using Furazolidone+metronidazole as Furazolidone+metronidazole may cause blurred vision or dizziness that may affect the ability to drive or using machines. Furazolidone+metronidazole is safely given to children.

Uses of Furazolidone+metronidazole

Bacterial infection, Diarrhea, Dysentry, Intestinal infection

Medicinal Benefits

Furazolidone+metronidazole is a combination of two medicines namely furazolidone and metronidazole. is used to treat various infections caused by bacteria, dysentery and diarrhea. It is also used to treat intestinal infections, typhoid fever and skin infections. Furazolidone+metronidazole is effective to treat many types of bacterial infections. Furazolidone+metronidazole contains flurazolidone works by interfering with the protein synthesis, a mechanism which is important for survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively they help in treating the disease effectively.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Syrup/suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Furazolidone+metronidazole

  • Nausea
  • Dizziness
  • Vomiting
  • Abdominal distress
  • Vertigo
  • Dryness in mouth
  • Headache
  • Metallic taste
  • Ototoxicity
  • Dark yellow to brown discoloration of urine

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to furazolidone, metronidazole or any other antibacterial or anti amoebic agents, please inform your doctor to avoid any unwanted side-effects. Furazolidone+metronidazole should not be taken in the conditions like liver disease, kidney disease. Before taking Furazolidone+metronidazole inform your doctor if you have fits disorder, numbness or pain of feet or hands. Furazolidone+metronidazole may low white blood cell count (leukopenia). Furazolidone+metronidazole may cause convulsions (rapid contraction and relaxation of body muscles), if you observe these symptoms immediately contact your doctor. Discontinue the Furazolidone+metronidazole if any signs of low blood count observed. Immediately inform your doctor if you experience swelling of the face, tongue, throat, itchy rash or breathing difficulties while taking this Furazolidone+metronidazole. Furazolidone+metronidazole is safely given to children above one month year of age. It is advisable to you do not drive while using Furazolidone+metronidazole as Furazolidone+metronidazole may cause blurred vision or dizziness that may affect the ability to drive or use machines. It is not advisable to stop taking Furazolidone+metronidazole suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed.

Drug Interactions

Drug-Drug Interaction: This medicine may have an interaction with antiparkinson’s medicine (selegiline, rasagiline, apomorphine), a medicine used in cough (dextromethorphan), antiallergic (phenylephrine, pseudoephedrine), medicine for the fit disorder (phenobarbital), medicine for enlarged prostate gland (a gland between the bladder and penis) (alfuzosin), medicine for heart disease (amiodarone), antibiotic (clarithromycin), antacid (omeprazole).

Drug-Food Interaction: Furazolidone+metronidazole interacts with foods with high tyramine. Avoid drinking alcohol as it may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, headache or redness of the face.

Drug-Disease Interaction: Furazolidone+metronidazole may interact in patients with liver disease and gastrointestinal disease.

Drug-Drug Interactions Checker List:

  • SELEGILINE
  • RASAGILINE
  • APOMORPHINE
  • DEXTROMETHORPHAN
  • PHENYLEPHRINE
  • PSEUDOEPHEDRINE
  • PHENOBARBITAL
  • ALFUZOSIN
  • AMIODARONE
  • CLARITHROMYCIN
  • OMEPRAZOLE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Drinking alcohol while taking this Furazolidone+metronidazole may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, headache or redness of the face.

    • Safety Warning

      Pregnancy

      unsafe

      Furazolidone+metronidazole should not be taken if you are pregnant or planning to have a baby. If you become pregnant while taking Furazolidone+metronidazole, stop taking the medication, and contact your doctor immediately. Metronidazole should not be given in the first trimester of the pregnancy as it may cause harm to the fetus.

    • Safety Warning

      Breast Feeding

      caution

      Take Furazolidone+metronidazole only when prescribed, Furazolidone+metronidazole contains ‘metronidazole’ which is known to pass on in a limited quantity via breast milk to the child. Consult your doctor for further advice.

    • Safety Warning

      Driving

      caution

      Do not drive while using Furazolidone+metronidazole as Furazolidone+metronidazole may cause blurred vision or dizziness that may affect the ability to drive or using machines.

    • Safety Warning

      Liver

      caution

      Furazolidone+metronidazole to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Furazolidone+metronidazole to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      caution

      Furazolidone+metronidazole can be given to the children for typhoid fever, diarrhea, a stomach infection, amoebiasis, abdominal infection, diarrhea and intestinal infection only when prescribed by a child specialist.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola or chocolate. Furazolidone+metronidazole may increase nervousness, sleeplessness and anxiety caused by caffeine.
    • Probiotics should be taken after taking the full course of Furazolidone+metronidazole in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria. 
    • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Furazolidone+metronidazole.
    • Avoid intake of alcoholic beverages with Furazolidone+metronidazole as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Furazolidone+metronidazole in fighting off infections.

    Special Advise

    You should consult a doctor if you have symptoms associated with dehydration like dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness.

    Patients Concern

    Disease/Condition Glossary

    Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills and fatigue. Bacteria are of various forms comprising commonly of spherical, rod and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can become infected with a bacterial infection. People with weak immune systems or taking immunosuppressive medicine can make them more prone to bacterial infection.

    Diarrhea: It is the increase in bowel movement leading to increased and loose motions. 

    Dysentery: It is inflammation of the intestine, particularly the colon, caused by the bacteria Shigella.

    FAQs

    Yes, Furazolidone+metronidazole is known to cause dry mouth, especially when you start taking Furazolidone+metronidazole. If you feel excessively thirsty, do frequent mouth rinses, and increase fluid intake.

    Furazolidone+metronidazole helps in the treatment of various bacterial infections, diarrhea, and dysentery. Furazolidone+metronidazole contains flurazolidone works by interfering with the protein synthesis, a mechanism which is important for survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively they help in treating the disease effectively.

    Yes, Furazolidone+metronidazole may lead to temporary metallic taste. This metallic taste can be reduced by chewing mints, sugar-free gum and brushing teeth after the food.

    No, do not stop taking Furazolidone+metronidazole and complete the full course of treatment even if you feel well. Your symptoms may enhance before the infection is completely treated.

    Yes, Furazolidone+metronidazole may cause nausea and vomiting in some patients. You are recommended to take Furazolidone+metronidazole with meals to avoid this. If you still vomit or feel nauseous, please consult your doctor.

    No, you are recommended not to take Furazolidone+metronidazole with other antibiotics. Furazolidone+metronidazole is an antibiotic medicine that is used to treat parasitic and amoebic infections. When taken along with other antibiotics, Furazolidone+metronidazole may lose its efficiency or it might result in unwanted side effects.

    Available Medicines for

    Furazolidone+metronidazole

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