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Gabapentin+mecobalamin

About

Gabapentin+mecobalamin belongs to a group of medicines called 'anticonvulsants' used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia and restless leg syndrome in adults and children above 3 years of age. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Gabapentin+mecobalamin is a combination of two medicines: Gabapentin (anti-convulsant), Mecobalamin (vitamin B12). Gabapentin treats seizures by balancing a chemical messenger in the brain called a neurotransmitter, thereby decreasing its abnormal excitement in the brain. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Together, Gabapentin+mecobalamin helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders. 

Take Gabapentin+mecobalamin as prescribed by your doctor. You are advised to take Gabapentin+mecobalamin for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience dizziness, tiredness, sleepiness and uncoordinated body movements. Most of these side effects of Gabapentin+mecobalamin do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Gabapentin+mecobalamin for as long as your doctor has prescribed. Please do not stop taking Gabapentin+mecobalamin without consulting your doctor as it could cause withdrawal symptoms. Keep your doctor informed about your health condition and medicines to rule out any side-effects. Gabapentin+mecobalamin causes drowsiness and dizziness, so drive only if you are alert. Gabapentin+mecobalamin should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Gabapentin+mecobalamin as it could lead to increased dizziness and sleepiness. Do not take Gabapentin+mecobalamin if you are pregnant or breastfeeding unless prescribed by the doctor.

Uses of Gabapentin+mecobalamin

Neuropathic pain, Epilepsy (fits)

Medicinal Benefits

Gabapentin+mecobalamin belongs to a group of medicines called 'anticonvulsants' used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia and restless leg syndrome in adults and children above 3 years of age. Gabapentin+mecobalamin is a combination of two medicines: Gabapentin (anti-convulsant), Mecobalamin (vitamin B12). Gabapentin treats seizures by balancing a chemical messenger in the brain called a neurotransmitter, thereby decreasing its abnormal excitement in the brain. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Together, Gabapentin+mecobalamin helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Directions for Use

Take Gabapentin+mecobalamin with or without food. Swallow Gabapentin+mecobalamin as a whole with a glass of water, do not chew or break the tablet/capsule. Based on your medical condition, your doctor will decide how long you need to take Gabapentin+mecobalamin.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gabapentin+mecobalamin

  • Dizziness
  • Tiredness
  • Sleepiness
  • Uncoordinated body movement

In-Depth Precautions and Warning

Drug Warnings

Do not take Gabapentin+mecobalamin if you are allergic to any of its contents. Inform your doctor before taking Gabapentin+mecobalamin if you have heart problems or bipolar syndrome, nervous system disorders or older than 65. Consult your doctor if you are on hemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea or vomiting. Please do not stop taking Gabapentin+mecobalamin without consulting your doctor as it could cause withdrawal symptoms. Gabapentin+mecobalamin causes drowsiness and dizziness, so drive only if you are alert. Gabapentin+mecobalamin should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Gabapentin+mecobalamin as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Gabapentin+mecobalamin should not be given to children below three years as the safety and effectiveness have not been established. Do not take Gabapentin+mecobalamin if you are pregnant or breastfeeding unless prescribed by the doctor.

Drug Interactions

Drug-Drug Interactions: Gabapentin+mecobalamin may have interaction with anti-diabetic (metformin), antibiotic (chloramphenicol), and antacids (cimetidine, dexlansoprazole, esomeprazole, omeprazole, pantoprazole, rabeprazole, ranitidine), water pills/ diuretics (amiloride), antidepressants (citalopram, duloxetine, fluoxetine), and anti-convulsant (pregabalin).

Drug-Food Interactions: Avoid alcohol consumption while taking Gabapentin+mecobalamin as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Gabapentin+mecobalamin may interact with disease conditions such as suicidal tendency, renal dysfunction, and depression.

Drug-Drug Interactions Checker List:

  • METFORMIN
  • CHLORAMPHENICOL
  • CIMETIDINE
  • DEXLANSOPRAZOLE
  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • RABEPRAZOLE
  • RANITIDINE
  • AMILORIDE
  • CITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • PREGABALIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Gabapentin+mecobalamin as it may increase dizziness and sleepiness.

    • Safety Warning

      Pregnancy

      caution

      Avoid taking Gabapentin+mecobalamin if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking Gabapentin+mecobalamin; your doctor will decide whether Gabapentin+mecobalamin can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      unsafe

      Gabapentin+mecobalamin causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Gabapentin+mecobalamin should not be given to children less than 3 years of age. For the above 3 years of age, close monitoring is required.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include food rich in vitamin B and D in your diet to improve nerve health and prevent nerve pain.
    • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
    • Exercising regularly helps in improving overall health and combating pain. 
    • Rest well, get plenty of sleep.
    • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.
    • Avoid smoking and alcohol consumption.
    • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
    • Physical relaxation and massages can help provide symptomatic relief.
    • Learn about techniques for sitting, stretching, moving and standing from a physical or occupational therapist. These can help prevent pain.
    • Acupuncture can be helpful by stimulating pressure points.
    • Using essential oils for massages can help increase circulation and boosts healing.

    Special Advise

    • Close monitoring for suicidal thoughts/behaviour is required for people using Gabapentin+mecobalamin.
    • Not for use in children less than 3 years of age.
    • Using Gabapentin+mecobalamin in children 3-12 years of age can cause emotional changes, aggressive behaviour, concentration problems, restlessness, school performance changes and hyperactivity.

    Patients Concern

    Disease/Condition Glossary

    Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

    FAQs

    People taking Gabapentin+mecobalamin should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.

    Viral infection, fever, nausea, vomiting, trouble speaking and jerky movements are the common side effects of gabapentin present in Gabapentin+mecobalamin.

    If Gabapentin+mecobalamin is taken along with antacid medicines containing aluminium and magnesium, it may lower the stomach's absorption of Gabapentin+mecobalamin. To avoid this, maintain a gap of two hours between Gabapentin+mecobalamin and antacid medicines.

    The nerves in the periphery of your body, like the nerves in your fingertip and toes are known as peripheral nerves, and any injury to one or more of these nerves is known as peripheral neuropathy. These nerves transmit messages from/to the brain and spinal cord to/from the rest of the body. Damage caused to these nerves stops them from working properly, and the messages moving between your central and peripheral nervous system get disturbed.

    Gabapentin+mecobalamin is not a sedative drug. However, it has been known to cause drowsiness and sleepiness. You should not take up activities like driving and activities which require mental alertness along with physical coordination.

    Yes, Gabapentin+mecobalamin may rarely cause weight gain, but is not experienced by every one. Follow regular diet and exercise in order to maintain healthy weight.

    Available Medicines for

    Gabapentin+mecobalamin

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