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HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE

About

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE belongs to the class of sex hormones used to treat female infertility and male hypogonadism. Female infertility is when a woman is unable to get pregnant within a year of trying. Male hypogonadism is when the body does not produce enough hormones responsible for masculine growth in men. Cryptorchidism is a condition in which testes don’t descend into the scrotum (bag of skin present below the penis).

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE contains ‘human chorionic gonadotropin and sodium chloride’. It stimulates the production of sex hormones such as testosterone in men and progesterone in women. It can stimulate ovulation (egg production) in women and improve sperm production in men.

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE is available in the form of injection. It is usually administered by a healthcare professional. The common side-effects of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE are pain at the injection site, headache, irritability, restlessness, depression, fatigue, oedema (swelling), early puberty and gynecomastia (swelling of breast tissue in men).

Do not take HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE if you are allergic to ‘human chorionic gonadotrophin’ or any other ingredients present in it. It should not be used in patients with conditions such as early puberty, prostatic cancer or other androgen-dependent cancers, unexplained vaginal bleeding, uncontrolled thyroid or adrenal gland dysfunction and ovarian cysts. It is not recommended for use in pregnant women and should be used with caution in breastfeeding mothers.

Uses of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE

Female infertility, male hypogonadism.

Medicinal Benefits

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE contains ‘human chorionic gonadotropin’, which belongs to the ‘sex hormones’ class. It is used in treating female infertility in whom the cause of ovulation problems is a secondary ovarian failure (normal ovaries that don’t function properly). It can also treat male hypogonadism in which the testes are normal but don’t function properly.

Directions for Use

For intramuscular (IM) or subcutaneous (SC) use only. HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE will be administered by a healthcare professional.

Storage

Store in a cool and dry place away from sunlight

Side Effects of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE

  • Injection site pain
  • Headache
  • Irritability
  • Restlessness
  • Depression
  • Fatigue
  • Oedema (swelling)
  • Early puberty
  • Gynecomastia (swelling of breast tissue in men)

In-Depth Precautions and Warning

Drug Warnings

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE may cause multiple pregnancies (pregnant with more than one child at the same time). So, discuss with your doctor the possible risks of this medicine. It can increase the risk of blood clots. An anaphylactic reaction such as shortness of breath, hives, loss of consciousness, low pulse and shock have been reported with HCG products derived from urine. In some cases, worsening of preexisting ovarian cysts or sudden ovary enlargement can be seen. So, regular monitoring is required. Early puberty may be seen in children. In such cases, discontinue therapy immediately and consult a doctor.

Drug Interactions

Drug-drug interactions: No interactions found.

Drug-food interactions: No interactions found.

Drug-disease interactions: HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE is contraindicated in conditions such as early puberty and androgen-dependent cancers, unexplained vaginal bleeding, uncontrolled thyroid or adrenal gland dysfunction, and ovarian cysts. Should use it with caution in patients with heart or kidney disease, epilepsy (fits), migraine (persistent headache), or asthma (a lung problem).

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Alcohol may interfere with the efficacy of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE.

  • Safety Warning

    Pregnancy

    unsafe

    HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE is a category X drug. HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE should not use it in pregnant women as it may cause birth defects/congenital disabilities.

  • Safety Warning

    Breast Feeding

    caution

    Information regarding the use of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE during breastfeeding is not available. Please consult your doctor.

  • Safety Warning

    Driving

    safe if prescribed

    HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE may not affect your ability to drive.

  • Safety Warning

    Liver

    caution

    Limited information is available regarding the usage of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Kidney

    caution

    Limited information is available regarding the usage of HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Children

    caution

    HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE may cause early puberty. So, should discontinue therapy immediately if the children develop any signs of early puberty.

Habit Forming

No

Diet & Lifestyle Advise

  • Consume a healthy diet that is rich in fibre, proteins and low in carbohydrates, fats.
  • Avoid processed or high-sugar foods.
  • Stay active and shed excess weight if you are overweight or obese. Do not perform intense exercises as they may negatively impact your reproductive health. Increase the intensity of exercise gradually.
  • Being underweight may also affect fertility. So, prepare a diet chart that can help you to gain weight healthily.
  • Avoid stress as it may affect your fertility. Try relaxation techniques and receive support and counselling if necessary.
  • Limit alcohol and caffeine intake.
  • Quit smoking.

Special Advise

  • To be sure HCG is helping your condition, your doctor will need to check you regularly. Do not miss any scheduled appointments.
  • Some women using this medicine have developed ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition. Call your doctor right away if you have any symptoms of OHSS like severe pelvic pain, swelling of the hands or legs, stomach pain and swelling, shortness of breath, weight gain, diarrhoea, nausea or vomiting or if you are urinating less than usual.

Patients Concern

Disease/Condition Glossary

Female infertility: When a woman is not able to become pregnant within a year of trying. If a woman gets pregnant but experiences miscarriages or stillbirths, it is also included in infertility.

Male hypogonadism: A condition in which hormones such as testosterone responsible for masculine growth in men are not produced enough in the body. It may cause decreased sexual desire, erectile dysfunction and low sperm production.

FAQs

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE contains ‘human chorionic gonadotropin and sodium chloride’ used to treat female infertility and male hypogonadism. It stimulates the production of sex hormones such as testosterone in men and progesterone in women. It can stimulate ovulation (egg production) in women and improve sperm production in men.

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE is not recommended for the treatment of obesity. It does not affect appetite loss and weight reduction.

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE should not be given to patients with thyroid problems. This medicine may cause an increase in the production of thyroid hormones and cause unwanted effects when used in patients with thyroid dysfunction.

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE may increase the chance of getting pregnant with more than one child (multiple pregnancies) in most cases. Discuss with your doctor the possible benefits and risks before taking HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE.

Human chorionic gonadotropin (HCG) is a hormone that helps a woman's egg usually to develop in her ovary and encourages the egg's release during ovulation.

Available Medicines for

HUMAN CHORIONIC GONADOTROPHIN+SODIUM CHLORIDE

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