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Human Insulin+insulin Isophane

About

Human Insulin+insulin Isophane is used for the treatment of both type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition that affects the way the body processes glucose. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, insulin is produced in large amounts, but it cannot act on the organs of the body.

Human Insulin+insulin Isophane is a combination of two drugs, namely: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Human Insulin+insulin Isophane suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby Human Insulin+insulin Isophane ensures rapid and consistent sugar control. 

Take Human Insulin+insulin Isophane as advised by your doctor. If you are not well trained to self-administer Human Insulin+insulin Isophane, ask your healthcare professional to administer it. In some cases, Human Insulin+insulin Isophane may cause certain common side effects like an allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects of Human Insulin+insulin Isophane do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Consult your doctor before taking Human Insulin+insulin Isophane if you are pregnant or breastfeeding. Human Insulin+insulin Isophane may cause drowsiness, so drive with caution. Avoid alcohol consumption along with Human Insulin+insulin Isophane as it may cause unpleasant side effects. Human Insulin+insulin Isophane should be given to children only if prescribed by the doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Human Insulin+insulin Isophane is a cold chain medicine, it has to be stored in the refrigerator between 2-8°C else its efficiency may be lost. Do not store in the freezer.

Uses of Human Insulin+insulin Isophane

Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

Medicinal Benefits

Human Insulin+insulin Isophane is a combination of two drugs, namely: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Human Insulin+insulin Isophane is used for the treatment of both type 1 and type 2 diabetes mellitus. Human Insulin+insulin Isophane suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby Human Insulin+insulin Isophane ensures rapid and consistent sugar control.  Human Insulin+insulin Isophane helps in improving the glycaemic control which in turn decreases the risk of progression of diabetes complications like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, and diabetic foot ulcer.

Directions for Use

Human Insulin+insulin Isophane should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks). It should never be administered intravenously or in the vein. If you are not well trained to self-administer Human Insulin+insulin Isophane, ask your healthcare professional to administer it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Human Insulin+insulin Isophane

  • Allergic reaction at the site of injection
  • Hypoglycemia (low blood glucose level)
  • Itching
  • Lipodystrophy (skin thickening or pits at the injection site)
  • Oedema (swelling)
  • Rashes
  • Weight gain

In-Depth Precautions and Warning

Drug Warnings

Do not take Human Insulin+insulin Isophane if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking Human Insulin+insulin Isophane if you are pregnant or breastfeeding. Human Insulin+insulin Isophane may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule. 

Drug Interactions

Drug-Drug Interaction: Human Insulin+insulin Isophane may interact with medicines such as pain killer (aspirin), antibiotic (ciprofloxacin), bronchodilators (albuterol, ipratropium), diuretic (furosemide), anti-hypertensive (metoprolol), anti-depressant (sertraline), oral hypoglycemic agents, monoamine oxidase inhibitors, anabolic steroids, glucocorticoids, thyroid hormones and sympathomimetics.

Drug-Food Interaction: Avoid consumption of alcohol along with Human Insulin+insulin Isophane as it may lead to unpleasant side effects.

Drug-Disease Interaction: Inform your doctor if you have kidney disease, liver disease, low potassium level (hypokalaemia), and low blood sugar/glucose level (hypoglycemia).

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • CIPROFLOXACIN
  • ALBUTEROL
  • IPRATROPIUM
  • FUROSEMIDE
  • METOPROLOL
  • SERTRALINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended not to consume alcohol along with Human Insulin+insulin Isophane to avoid unpleasant side effects. Alcohol may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      safe if prescribed

      It is safe to use Human Insulin+insulin Isophane during pregnancy if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      It is safe to use Human Insulin+insulin Isophane by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Driving

      caution

      Human Insulin+insulin Isophane may cause drowsiness and hypoglycemia (low blood sugar). Therefore, drive only if you are alert.

    • Safety Warning

      Liver

      caution

      Human Insulin+insulin Isophane should be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Human Insulin+insulin Isophane should be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      safe if prescribed

      Human Insulin+insulin Isophane can be given safely to children provided the dose has been prescribed by a child specialist.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include foods rich in healthy carbohydrates and fiber, fruits, whole grains, and vegetables in your diet.
    • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
    • Follow a healthy diet and walk for at least a few minutes to complement treatment with Human Insulin+insulin Isophane.
    • Maintain a healthy weight by exercising regularly.
    • Rest properly, and avoid stress by doing meditation or yoga.

    Special Advise

    • If you feel any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.  

    Patients Concern

    Disease/Condition Glossary

    Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types, namely: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

    FAQs

    Human Insulin+insulin Isophane suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby Human Insulin+insulin Isophane ensures rapid and consistent sugar control. 

    Human Insulin+insulin Isophane may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Human Insulin+insulin Isophane. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.

    Do not stop taking Human Insulin+insulin Isophane without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Human Insulin+insulin Isophane for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Human Insulin+insulin Isophane.

    Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.

    Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Human Insulin+insulin Isophane is taken along with other antidiabetic medicines.

    Available Medicines for

    Human Insulin+insulin Isophane

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