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HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID

About

HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is a combination medicine used to treat menstrual pain. It effectively treats menstrual cramps and discomfort caused during menstrual periods. A menstrual cramp is a pain that occurs in the lower abdomen, which happens just before or at the beginning of a menstrual period.

HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID consists of two medicines: Hyoscine butyl bromide and Mefenamic acid. Hyoscine butyl bromide is an anticholinergic drug that stops muscle contractions by relaxing the muscles in the stomach, intestine, and bladder. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclo-oxygenase (COX) enzymes. Further, it prevents the formation of chemical messengers, 'prostaglandins' (PGs) that cause pain and swelling. 

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID include nausea, vomiting, dry mouth, and heartburn. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Please tell your doctor if you are allergic to HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID or its components. Inform your doctor beforehand if you have liver, kidney or heart diseases, glaucoma, enlarged bowel (megacolon), myasthenia gravis (muscle weakness), gastrointestinal problems, high blood pressure, and asthma before starting HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID may cause drowsiness and dizziness, so drive with caution. You are advised to avoid alcohol intake while using HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID.

Uses of HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID

Menstrual pain.

Medicinal Benefits

HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID contains Hyoscine butyl bromide and Mefenamic acid. Hyoscine butyl bromide is an anticholinergic drug that stops muscle contractions by relaxing the muscles in the stomach, intestine, and bladder. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thus HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID treats menstrual pain, discomfort, and abdominal cramps.

Directions for Use

Swallow it as a whole with a glass of water; do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID

  • Nausea
  • Vomiting
  • Dry mouth
  • Heartburn 

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID. Inform your doctor beforehand if you have a history of liver, kidney or heart diseases, high blood pressure, diabetes, high cholesterol, stomach ulcer, ulcerative colitis (inflammation in the digestive tract), glaucoma, enlarged bowel (megacolon), myasthenia gravis (muscle weakness),  bleeding in the stomach, asthma, anaemia (lack of haemoglobin), and fluid retention (oedema) before starting HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID causes drowsiness, so drive with caution. Do not consume alcohol while using HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID. HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is not recommended in children below 12 years of age.

Drug Interactions

Drug-Drug Interaction: HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID may interact with anti-emetic (domperidone, metoclopramide), bronchodilator (salbutamol), anti-arrhythmic (quinidine, disopyramide), anti-Parkinson (amantadine), anti-cholinergic (tiotropium, ipratropium), anti-psychotic (haloperidol, fluphenazine), opiate analgesic (codeine), anti-depressant (amitriptyline, duloxetine, lithium, fluoxetine, sertraline), pain killers (aspirin, ibuprofen, celecoxib, diclofenac, naproxen), anti-gout (probenecid), immunosuppressants (cyclosporine, tacrolimus), anticoagulants (warfarin, heparin), anti-rheumatoid (methotrexate), anti-HIV (zidovudine), and abortion drugs (mifepristone).

Drug-Food Interaction: Avoiding alcohol may help avoid the side effects of HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID like drowsiness and dizziness.

Drug-Disease Interaction: HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID may have interactions with stomach ulcers, bleeding disorders, asthma, fluid retention, gastrointestinal problems, anaemia, heart failure, liver and kidney problems, high blood pressure, glaucoma, myasthenia gravis, blockage of the bowel, paralytic/obstructive ileus, and enlarged bowel.

Drug-Drug Interactions Checker List:

  • DOMPERIDONE
  • METOCLOPRAMIDE
  • SALBUTAMOL
  • QUINIDINE
  • DISOPYRAMIDE
  • AMANTADINE
  • TIOTROPIUM
  • IPRATROPIUM
  • HALOPERIDOL
  • FLUPHENAZINE
  • CODEINE
  • AMITRIPTYLINE
  • DULOXETINE
  • LITHIUM
  • FLUOXETINE
  • SERTRALINE
  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • DICLOFENAC
  • NAPROXEN
  • PROBENECID
  • CYCLOSPORINE
  • TACROLIMUS
  • WARFARIN
  • METHOTREXATE
  • ZIDOVUDINE
  • MIFEPRISTONE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID. Alcohol intake, along with HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID, may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is not recommended for use during pregnancy since animal studies showed harmful effects on the foetus. Please consult your doctor before taking HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is excreted in human milk. Please consult your doctor before taking HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID if you are lactating.

    • Safety Warning

      Driving

      caution

      HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID may make you feel dizzy, drowsy or tired. Do not drive or operate machinery if you experience these side effects.

    • Safety Warning

      Liver

      caution

      Please consult your doctor since HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID should be used with caution in patients with liver impairment/liver disease.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor since HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID should be used with caution in patients with kidney impairment/kidney disease.

    • Safety Warning

      Children

      unsafe

      HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is not recommended in children below 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
    • Performing yoga may also help in improving joint flexibility and pain management.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
    • Follow heat or cold therapy; apply a cold or hot compress on the joints for 15-20minutes regularly.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
    • Acupuncture, massage, and physical therapy may also be helpful.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
    • Avoid smoking and alcohol consumption.

    Special Advise

    • Let your doctor know that you are taking HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID if you are undergoing any medical tests.
    • Monitor your blood pressure regularly. 

    Patients Concern

    Disease/Condition Glossary

    Abdominal cramps: It is the throbbing pains that occur in the lower abdomen due to menstruation every month in females. Menstruation is the release of blood in women when the fertilization of an egg does not take place. In some women, the pain and discomfort caused due to menstruation are so severe that they have to take some medicine to lower the pain intensity. It generally occurs one to two days before the menses and lasts till the menses are over.

    FAQs

    HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is a combination drug that contains 'Mefenamic acid' and 'Hyoscine butyl bromide.' Mefenamic acid works by blocking the effect of a chemical messenger in your body, which is responsible for causing pain. Hyoscine butyl bromide stops the muscle contractions by relaxing the muscles in the stomach, intestine, and bladder. Collectively, both of them help to relieve pain, cramps, and discomfort caused during the menstrual period.

    HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is used to relieve menstrual (period) pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. Take only as prescribed by the doctor.

    Avoid taking HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID if you have stomach ulcers as HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID contains Mefenamic acid, which might increase the risk of stomach ulcers, perforation of the stomach and intestinal bleeding with higher doses.

    Dry mouth could be a side-effect of HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

    HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID is generally prescribed for short-term use. Do not take HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID for longer durations as it might increase the risk of heart problems and stomach bleeding.

    Available Medicines for

    HYOSCINE BUTYL BROMIDE+MEFENAMIC ACID

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