IBUPROFEN+TIZANIDINE
About
IBUPROFEN+TIZANIDINE belongs to the class of medications called ‘analgesics’ used in treating acute muscle spasms associated with low back pain. Low back pain, also called lumbago, is a condition that affects the lower portion of the spine. It often occurs due to injury, strain, or sprain in the muscles, bones, or ligaments present in the lower back. In most cases, the only symptom of this condition is a pain in the lower back.
IBUPROFEN+TIZANIDINE contains Ibuprofen and Tizanidine. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandins' production (chemical substances that cause pain and inflammation) at the affected site (muscle) and reduce pain. Tizanidine is a short-acting muscle relaxant. It works by reducing the activity of the nerves in the brain that control muscles. This effect helps to reduce muscle spasms, thereby improving pain and muscle movements.
You should take this medicine exactly as prescribed by the doctor. The common side-effects of IBUPROFEN+TIZANIDINE are drowsiness, tiredness, dizziness, low blood pressure, dry mouth, nausea, stomach upset, heartburn, abdominal pain, indigestion, and decrease or increase in heart rate. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
It is not recommended to take IBUPROFEN+TIZANIDINE if you are allergic to ibuprofen, tizanidine, NSAIDs, or any contents of this medicine. Do not take IBUPROFEN+TIZANIDINE if you have bleeding or ulcers in the stomach or intestine, severe liver, kidney, or heart problems, severe dehydration (due to vomiting or diarrhoea), active bleeding (including in the brain), and conditions that cause the abnormal formation of red blood cells. It is not recommended for use in children, adolescents, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as dose adjustments are necessary. Alcohol consumption may increase the risk of side-effects. IBUPROFEN+TIZANIDINE may cause drowsiness and dizziness, so do not drive or operate heavy machinery if you are fully alert.
Uses of IBUPROFEN+TIZANIDINE
Medicinal Benefits
IBUPROFEN+TIZANIDINE is used to treat acute pain associated with muscle spasms that usually occur due to muscle strains, sprains or injuries in the lower back. It contains ibuprofen and tizanidine. Ibuprofen can reduce pain, swelling and inflammation in the muscles, whereas tizanidine can reduce muscle spasms and pain. It provides fast relief from pain, within a few hours after taking this medicine. It reduces muscle stiffness and enables the easy movement of the muscle. It is well tolerated when taken at recommended doses. For the best results, rest and physical therapy are also essential along with this medicine as it will help to strengthen your back.
Directions for Use
Storage
Side Effects of IBUPROFEN+TIZANIDINE
- Drowsiness
- Tiredness
- Dizziness
- Low blood pressure
- Dry mouth
- Nausea
- Stomach upset
- Heartburn
- Abdominal pain
- Indigestion
- Decrease or increase in heart rate
In-Depth Precautions and Warning
Drug Warnings
Before taking IBUPROFEN+TIZANIDINE, inform your doctor if you have any liver, kidney, or heart problems, diabetes, high cholesterol, high blood pressure, respiratory problems, systemic lupus erythematosus (a skin disease), porphyria (an inherited blood disorder), blood clotting problems, and ulcerative colitis (inflammation of the colon). IBUPROFEN+TIZANIDINE increases the risk of ulcers, bleeding, and perforation in the stomach or intestine when taken in high doses. It may also increase the risk of heart attack or stroke when used in high doses. IBUPROFEN+TIZANIDINE may increase the risk of kidney damage, especially in patients who have liver, kidney, or heart problems, and who are taking water pills. IBUPROFEN+TIZANIDINE may affect the function of platelets (form clots) and prolong bleeding time, so it should be used with caution in patients with blood clotting problems. IBUPROFEN+TIZANIDINE is an anti-inflammatory and can mask the symptoms of an infection, so consult your doctor if you feel unwell while using this medicine.
Drug Interactions
Drug-Drug Interactions: IBUPROFEN+TIZANIDINE may interact with other NSAIDs, blood thinners (warfarin, heparin, clopidogrel, and ticlopidine), medicines used to treat abnormal heart rhythms (amiodarone, mexiletine, and propafenone), a medicine used to treat stomach ulcer (cimetidine), antibiotics (enoxacin, pefloxacin, and norfloxacin), painkiller (rofecoxib), oral contraceptives, medicines used to treat high blood pressure including water pills, beta-blockers (atenolol and propranolol), a medicine used to treat heart disease (digoxin), sleeping pill (temazepam), a medicine used to treat cancer (methotrexate), a medicine used to treat fits (phenytoin), antidepressants (lithium, paroxetine, and sertraline), a medicine used to treat high cholesterol (cholestyramine), anti-HIV drugs (zidovudine and ritonavir), a medicine used to treat gout (probenecid), muscle relaxant (baclofen), and antifungal medicines (voriconazole and fluconazole).
Drug-Food Interactions: IBUPROFEN+TIZANIDINE may interact with alcohol and increase the risk of side-effects.
Drug-Disease Interactions: IBUPROFEN+TIZANIDINE should not be used in patients with bleeding or ulcers in the stomach or intestine, severe liver, kidney, or heart problems, severe dehydration (due to vomiting or diarrhoea), active bleeding (including in the brain), and conditions that cause the abnormal formation of red blood cells.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeConsumption of alcohol increases the risk of side-effects, such as drowsiness, liver damage, and bleeding in the stomach.
Pregnancy
unsafeIBUPROFEN+TIZANIDINE is usually not recommended during pregnancy, especially if you are more than six months pregnant as it may cause harmful effects to the unborn baby.
Breast Feeding
unsafeIBUPROFEN+TIZANIDINE may pass into breastmilk and cause unwanted effects in the nursing baby. So, it is not prescribed in breastfeeding mothers. However, if prescribed, the doctor may advise you to stop breastfeeding while using this medicine.
Driving
unsafeIBUPROFEN+TIZANIDINE may cause dizziness or drowsiness, so do not drive or operate heavy machinery if you are not fully alert.
Liver
cautionIBUPROFEN+TIZANIDINE should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionIBUPROFEN+TIZANIDINE should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
unsafeIBUPROFEN+TIZANIDINE is not recommended for use in children and adolescents.
Habit Forming
Diet & Lifestyle Advise
- Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear, and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
- Deep tissue massages with the help of muscle massagers are considered helpful.
- Avoid wearing tight-fitting clothes, instead, wear loose garments.
- Rest well and get optimal sleep (at least 8 hours for adults).
- Hot or cold therapy can help treat muscle spasms.
- Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
- Try to include glycine (protein) in your daily diet, which is good food for your muscle.
Patients Concern
Disease/Condition Glossary
Low back pain: It is also called lumbago. It is a common condition that occurs due to injury, sprain, or strain to the muscles, bones, or ligaments present in the lower portion of the spine. The common causes are lack of regular exercise, improper postural lifting, bad or poor posture, and fracture. Pain in the lower back is the only symptom often seen with this condition. Analgesics (pain relievers) and physical therapy can help to relieve pain. Exercise helps in muscle stretching so that they are less likely to spasm, tear and sprain.
FAQs
IBUPROFEN+TIZANIDINE contains Ibuprofen and Tizanidine. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandins' production (chemical substances that cause pain and inflammation) at the affected site (muscle) and reduce pain. Tizanidine is a short-acting muscle relaxant. It works by reducing the activity of the nerves in the brain that control muscles. It helps to reduce muscle spasms, thereby improving pain and muscle movements. Together, IBUPROFEN+TIZANIDINE can effectively reduce low back pain.
IBUPROFEN+TIZANIDINE is probably safe and well-tolerated in diabetic patients when taken at recommended doses. However, higher doses or prolonged use may affect sugar levels and cause unwanted effects. So, let your doctor know that you have diabetes before taking IBUPROFEN+TIZANIDINE.
IBUPROFEN+TIZANIDINE may cause drowsiness and dizziness. So, it is advised not to consume alcohol as it may cause excessive drowsiness. It is also not advised to drive or operate heavy machinery if you are not fully alert.
IBUPROFEN+TIZANIDINE may cause kidney damage when taken in high doses for a long duration. So, do not increase the dose or use it for prolonged periods than intended by the doctor.
IBUPROFEN+TIZANIDINE should not be used in patients with stomach ulcers as it may elevate the symptoms and worsen the condition. So, inform your doctor that you have a stomach ulcer before taking this medicine.
