Insulin Glulisine

Insulin Glulisine is rapid-acting insulin for the treatment of diabetes mellitus in both children (above six years of age) and adults. The active ingredient in Insulin Glulisine is insulin glulisine. Insulin Glulisine is a recombinant human insulin analogue that is equipotent to regular human insulin. Insulin glulisine has a more rapid onset of action and a shorter duration of action than regular human insulin. Diabetes is a lifelong condition that causes a person's blood sugar level to become too high.

Insulin Glulisine is a fast-acting insulin that works rapidly to normalise blood sugar levels after a meal. It typically begins working within 10-20 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours. Due to this short action, Insulin Glulisine should normally be taken in combination with intermediate-acting or long-acting insulin preparations. Insulin Glulisine works by ensuring rapid and consistent sugar control. Insulin Glulisine is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Prevents the risk of having severe complications of diabetes.

The primary role of insulin and insulin analogues, including insulin glulisine, is glucose metabolism control. Insulin lowers blood glucose levels by stimulating peripheral glucose uptake, particularly skeletal muscle and fat, and inhibiting hepatic glucose production. Insulin glulisine takes effect about twice as fast as regular human insulin and completes the glucose-lowering effect about 2 hours earlier than regular human insulin.

Your doctor will advise you on how to use Insulin Glulisine. It should be administered at least 0-15 minutes before or soon after meals. The common side effects of Insulin Glulisine are hypokalaemia (low potassium), hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin), which may occur at the injection site. Most of these side effects of Insulin Glulisine do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Insulin Glulisine of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Insulin Glulisine if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Insulin Glulisine, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Insulin Glulisine is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

The primary role of insulin and insulin analogues, including insulin glulisine, is glucose metabolism control. Insulin lowers blood glucose levels by stimulating peripheral glucose uptake, particularly skeletal muscle and fat, and inhibiting hepatic glucose production. Insulin Glulisine works by ensuring rapid and consistent sugar control. Insulin Glulisine is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver. Insulin Glulisine helps in improving the glycaemic control, which in turn decreases the risk of progression of complications of diabetes like damage of the retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Insulin Glulisine can be safely prescribed to the diabetic mother during pregnancy and lactation.

Insulin Glulisine is administered at least 15 minutes before a meal or 20 minutes after starting a meal in the abdomen or thigh region. It can be also given intravenously (IV) with 0.9% sodium chloride infusion. However subcutaneous injection of Insulin Glulisine in the abdomen region ensures faster absorption compared to other injection sites. Insulin Glulisine is usually given once or twice daily when both rapid and prolonged effect of insulin is desired. In the initial requirement, the dose requirement is usually between 0.3 and 1.0 IU/kg per day. An injection of Insulin Glulisine should be followed within 30 minutes by a meal or snack containing sugar/glucose (carbohydrates). If you are not well trained to self-administer Insulin Glulisine, ask healthcare professional to administer it. Procedure for self-injecting insulin: • You should wash your hand first before injecting insulin. • Then roll the insulin bottle and wipe the bottle top. • Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed. • Push the needle into the bottle and push syringe plunger down. • Now once again pull the plunger down to an appropriate number of units as prescribed by the doctor. • Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin and push the needle into the skin and then push the plunger in. • The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected. • After injecting the insulin pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Store in a cool and dry place away from sunlight

• Injection site reactions (such as reddening, unusually intense pain on injection, itching, hives, swelling or inflammation)
• Hypoglycaemia (low blood sugar level)
• Hypokalaemia (low potassium)
• Lipodystrophy (fat deposition under the skin)
• Rash
• Pruritus (itchy skin)