Ipratropium Bromide+salbutamol
About
Ipratropium Bromide+salbutamol is a combination of medications primarily used to treat or prevent chronic obstructive pulmonary disease (COPD) symptoms, like shortness of breath, coughing, or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath due to a damaged air sac) and chronic bronchitis (inflammation and narrowing of the lining of airways or bronchial tubes).
Ipratropium Bromide+salbutamol contains Ipratropium bromide (anti-cholinergic) and Salbutamol (bronchodilator). Together, Ipratropium Bromide+salbutamol works by relaxing muscles and widening the lungs' airways. Thereby allowing them to breathe easily and providing relief from symptoms such as shortness of breath, coughing, or wheezing (whistling sound while breathing).
Ipratropium Bromide+salbutamol is for inhalation only. Your doctor will recommend how often you take Ipratropium Bromide+salbutamol based on your medical condition. Some people may experience headaches, sore throat, dry mouth, runny or stuffy nose, pain, cough with mucus, sneezing, chest tightness, difficulty breathing, dizziness, nervousness, tiredness, irregular heartbeats, and vomiting. Most of these side effects of Ipratropium Bromide+salbutamol do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Ipratropium Bromide+salbutamol or any other medicines, pregnant or breastfeeding, please inform your doctor before using Ipratropium Bromide+salbutamol. If you experience difficulty breathing, please consult a doctor immediately to prescribe an alternative medicine. Do not use Ipratropium Bromide+salbutamol to treat sudden severe breathing problems or as a rescue inhaler. Do not use Ipratropium Bromide+salbutamol in more than the prescribed doses as it may lead to severe heart or lung problems. Regular monitoring of potassium levels is recommended, while taking a prolonged intake of Ipratropium Bromide+salbutamol may cause low potassium levels in the blood. Please do not use or store Ipratropium Bromide+salbutamol near open flame or heat as it may burst the container. If you have high blood pressure, diabetes fits, enlarged prostate, glaucoma, thyroid or heart problems, bladder obstruction, or other urinary problems, inform your doctor before taking Ipratropium Bromide+salbutamol.
Uses of Ipratropium Bromide+salbutamol
Medicinal Benefits
Ipratropium Bromide+salbutamol is a combination of two bronchodilators: Ipratropium bromide (anti-cholinergic) and Salbutamol (bronchodilator). Together, Ipratropium Bromide+salbutamol works by relaxing muscles and widening the lungs' airways. Thereby allowing them to breathe easily and providing relief from symptoms such as shortness of breath, coughing, or wheezing (whistling sound while breathing).
Directions for Use
Storage
Side Effects of Ipratropium Bromide+salbutamol
- Headache
- Dry mouth
- Sore throat
- Runny or stuffy nose
- Cough with mucus
- Sneezing
- Chest tightness
- Difficulty in breathing
- Dizziness
- Nervousness
- Irregular heartbeat
- Muscle cramps
In-Depth Precautions and Warning
Drug Warnings
Please tell your doctor if you are allergic to Ipratropium Bromide+salbutamol or other ingredients. If you are pregnant or breastfeeding, please inform your doctor before using Ipratropium Bromide+salbutamol. If you experience severe difficulty in breathing, please consult a doctor immediately. Do not use Ipratropium Bromide+salbutamol in more than the prescribed doses as it may lead to severe heart or lung problems. If you have high blood pressure, diabetes, epilepsy (fits), enlarged prostate, glaucoma, thyroid or heart problems, bladder obstruction, or other urinary problems, inform your doctor before taking Ipratropium Bromide+salbutamol. Regular monitoring of potassium levels is recommended while taking Ipratropium Bromide+salbutamol as it may cause low potassium levels in the blood. However, if you experience irregular heartbeats, leg cramps, extreme thirst, constipation, increased urination, muscle weakness, numbness, or tingling, please consult a doctor immediately, as these might be signs of low potassium. Please do not use or store Ipratropium Bromide+salbutamol near open flame or heat as it may burst the container. Bronchodilators like salbutamol in Ipratropium Bromide+salbutamol can cause a rise in blood sugar levels; hence diabetic patients should monitor their blood glucose levels and use this medicine only with a doctor's advice.
Drug Interactions
Drug-Drug Interactions: Ipratropium Bromide+salbutamol may interact with bronchodilators (salmeterol, vilanterol, formoterol, tiotropium), steroids (budesonide, prednisone, prednisolone), drugs used to lower high blood pressure (atenolol, metoprolol, propranolol, carvedilol, labetalol, sotalol, timolol), water pills (furosemide, amiloride, bumetanide), antidepressants (linezolid, rasagiline, selegiline, tranylcypromine, imipramine, amitriptyline), antifungals (itraconazole, ketoconazole), HIV medicines (atazanavir, ritonavir, nelfinavir, indinavir, cobicistat, saquinavir), medicines treating nausea and vomiting (ondansetron), antiparkinson drug (levodopa), heart-related medicines (atropine).
Drug-Food Interactions: Ipratropium Bromide+salbutamol may interact with caffeine. Therefore, avoid or limit the intake of caffeinated beverages, foods, or dietary supplements with Ipratropium Bromide+salbutamol as it may increase the risk of adverse effects.
Drug-Disease Interactions: If you have high blood pressure, diabetes, fits, enlarged prostate, glaucoma, thyroid or heart problems, bladder obstruction, or other urinary problems, inform your doctor before taking the Ipratropium Bromide+salbutamol.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThe interaction of Ipratropium Bromide+salbutamol with alcohol is unknown. However, it is advisable to limit or avoid the consumption of alcohol.
Pregnancy
cautionIpratropium Bromide+salbutamol, a pregnancy category C drug may cause cleft palate and limb defects in newborns when used by pregnant women. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Ipratropium Bromide+salbutamol.
Breast Feeding
cautionSalbutamol, present in Ipratropium Bromide+salbutamol, is excreted in human milk. So, it is advisable to avoid breastfeeding while using Ipratropium Bromide+salbutamol. Ipratropium Bromide+salbutamol should be given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.
Driving
cautionIpratropium Bromide+salbutamol may cause blurred vision or dizziness in some people. Therefore, avoid driving if you notice any changes in vision or feel dizzy after taking Ipratropium Bromide+salbutamol.
Liver
cautionTake Ipratropium Bromide+salbutamol with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionIpratropium Bromide+salbutamol should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Ipratropium Bromide+salbutamol.
Children
cautionIpratropium Bromide+salbutamol is not recommended for children below 12 years of age. However, please consult a doctor before using Ipratropium Bromide+salbutamol in children.
Habit Forming
Diet & Lifestyle Advise
- Eat foods rich in potassium, such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroot, as potassium is important for lung function, and a potassium deficiency may cause breathing problems.
- Drink plenty of fluids daily to thin mucus, making it easier to cough out.
- Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas, and potatoes with skin.
- Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks like red bull.
- Eat protein-rich foods such as meat, fish (particularly salmon, sardines, and mackerel), eggs, and poultry.
- Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
- Quit smoking may reduce the effectiveness of the Ipratropium Bromide+salbutamol and irritate the lungs worsening breathing problems.
Special Advise
- Regularly monitor blood sugar levels while taking Ipratropium Bromide+salbutamol, especially if you have diabetes, as Ipratropium Bromide+salbutamol may increase blood sugar levels.
- Monitor blood potassium levels while taking Ipratropium Bromide+salbutamol, especially in asthma patients, as it may cause low potassium levels in the blood.
- Avoid contact of Ipratropium Bromide+salbutamol with eyes, especially if you have glaucoma (damaged eye nerve due to increased eye pressure), as it may worsen the condition and cause eye irritation or blurred vision.
- The fungal infection might occur in your mouth and throat, so it is advisable to gargle with warm water after each inhalation of Ipratropium Bromide+salbutamol.
Patients Concern
Disease/Condition Glossary
Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath due to damaged air sacs) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco and exposure to air pollutants like asbestos and chemicals/fumes. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).
FAQs
Ipratropium Bromide+salbutamol is used to treat and prevent respiratory disorders like chronic obstructive pulmonary disease (COPD). Ipratropium Bromide+salbutamol consists of Ipratropium bromide (anticholinergic) and Salbutamol (bronchodilator) that relax the airway's muscles and increases airflow to the lungs. It makes breathing easier by widening the airways.
Ipratropium Bromide+salbutamol can cause hypokalaemia in some patients leading to cardiovascular effects. Please consult your doctor before taking Ipratropium Bromide+salbutamol if you are a hypokalaemia patient or more susceptible to it.
Ipratropium bromide in Ipratropium Bromide+salbutamol may increase intraocular pressure. This may result in precipitation or worsening of narrow-angle glaucoma (damaged eye nerve due to increased eye pressure). Therefore, Ipratropium Bromide+salbutamol should be used with caution in patients with narrow-angle glaucoma. Inform your doctor if you have glaucoma before taking Ipratropium Bromide+salbutamol. Your doctor will weigh the benefits and potential risks before prescribing Ipratropium Bromide+salbutamol.
Bronchodilators like salbutamol in Ipratropium Bromide+salbutamol may cause rapid and irregular heartbeat, blood pressure changes, and electrocardiogram (ECG) changes. Please seek medical advice before using Ipratropium Bromide+salbutamol if you are a heart disease patient.
No, you are not recommended to take atenolol with Ipratropium Bromide+salbutamol as it may reduce both the medicine's effectiveness. Also, atenolol may cause a narrowing of airways sometimes, which may trigger severe asthmatic attacks or worsen breathing problems. However, please consult a doctor before using other medicines with a Ipratropium Bromide+salbutamol.
Salbutamol in Ipratropium Bromide+salbutamol can cause a rise in blood glucose levels. Hence therapy with Ipratropium Bromide+salbutamol is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so the dose can be adjusted accordingly.
No, Ipratropium Bromide+salbutamol is not useful in relieving sudden breathing problems. Consult your doctor for another rescue inhaler for sudden breathing problems.
