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Ivermectin

About

Ivermectin belongs to the class of anti-parasitic medicines, also known as anthelmintics. It is a widely used medication to treat various infections caused by parasites, including strongyloidiasis (a roundworm infection) and control onchocerciasis (a worm infection that affects skin and eyes). These parasitic infections can affect the quality of life and lead to life-threatening conditions if left untreated, especially in people with weakened defence (immune) systems.

Ivermectin contains ivermectin, which works by attaching to the inside of the parasite. It finally paralyzes and destroys the parasite or it prevents adult parasites from creating larvae for a while. Thus it effectively treats parasitic infections.

Take this medication as advised by your doctor. Do not alter the dose without your doctor’s advice. Common side-effects of Ivermectin are headache, dizziness, muscle pain, nausea, or upset stomach. You may also experience orthostatic hypotension (dizziness when getting up too quickly from a sitting or lying position). Most of these side effects of Ivermectin do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Ivermectin, inform your doctor if you are allergic to ivermectin or other medications. Do not consume Ivermectin if you are pregnant and breastfeeding without consulting the doctor. Tell your doctor if you are taking sedatives, anti-anxiety, or anti-epileptic drugs. Tell your doctor if you have a medical history of meningitis, human African trypanosomiasis, African sleeping sickness (an infection caused by the bite of tsetse fly in African countries), or illness that weakens the immune system, such as HIV or AIDS. Before taking the Ivermectin, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects.

Uses of Ivermectin

Parasitic infections [Strongyloidiasis (a threadworm infection), onchocerciasis (a worm infection)]

Medicinal Benefits

Ivermectin is an anti-parasitic medication. It can kill the parasites by acting on the nervous system. It starves the worms by inducing paralysis, consequently leading them to death. In the case of strongyloidiasis, it kills the parasites present in the intestine, completely treating the infection. In the case of onchocerciasis, it can only control the infection as it can kill the developing worms but not the adult worms.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ivermectin

  • Headache
  • Dizziness
  • Nausea
  • Muscle pain
  • Diarrhoea
  • Orthostatic hypotension
  • Head or neck pain
  • Confusion
  • Blurred vision
  • Seizures
  • Balance problems

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor if you are allergic to Ivermectin, antiparasitic medications, or any other medications. Tell your doctor if you use any prescription, nonprescription medicines, vitamins, nutritional supplements, or other herbal products. Inform your doctor if you are previously diagnosed with meningitis, human African trypanosomiasis (an infection caused by tsetse fly), or HIV. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor if you ever had loa loa infection (a worm infection) or if you ever lived in West or Central Africa. Contact your doctor immediately if you experience blurred vision, seizures, trouble walking, or neck pain.

Drug Interactions

Drug-Drug interactions: Ivermectin may interact with sedatives (phenobarbital and butalbital), anti-anxiety drugs (clonazepam and lorazepam), narcotic (sodium oxybate), and antiepileptic drugs (valproic acid).

Drug-Food interactions: Limit or avoid the consumption of alcoholic beverages.

Drug-Disease interactions: Ivermectin should be used with caution in patients with meningitis, human African trypanosomiasis, and HIV.

Drug-Drug Interactions Checker List:

  • PHENOBARBITAL
  • CLONAZEPAM
  • LORAZEPAM
  • VALPROIC ACID
  • BUTALBITAL
  • SODIUM OXYBATE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Ivermectin may interact with alcohol and increase the risk of side effects.

    • Safety Warning

      Pregnancy

      caution

      Ivermectin should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ivermectin.

    • Safety Warning

      Breast Feeding

      caution

      Ivermectin should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Ivermectin.

    • Safety Warning

      Driving

      caution

      Ivermectin may cause drowsiness and affect your ability to drive.

    • Safety Warning

      Liver

      caution

      Ivermectin should be used with caution in patients with liver problems. Take Ivermectin only under the supervision of a healthcare professional.

    • Safety Warning

      Kidney

      safe if prescribed

      Ivermectin can be used in patients with kidney problems only when prescribed by your doctor.

    • Safety Warning

      Children

      caution

      Ivermectin should be given to children when prescribed by a child specialist only.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • It is important to have a healthy diet high in nutrients and low in refined sugars and processed foods. Fibre is precious because it keeps your intestines constantly working while washing.
    • A nutrient-rich diet is also essential to improve your immune system, as parasites are flushed out of your body.
    • Garlic, honey, pumpkin, and papaya seeds are all labelled as anti-parasitic foods to be included in your diet. 
    • Try to choose a sugar-free, grain-free diet. 
    • Suggest limiting fruit consumption to reduce dietary sugars further.
    • Avoid eating raw or undercooked meat and seafood to prevent more parasitic infections after cleansing.

    Special Advise

    • To reduce dizziness upon standing, avoid standing up too quickly from a sitting or lying position. Get up slowly and rest your feet on the floor for a few minutes before standing up.

    Patients Concern

    Disease/Condition Glossary

    Strongyloidiasis is a threadworm infection. In this condition, a type of roundworm invades the intestine by entering into the body through the skin. It is characterized by symptoms such as abdominal pain, diarrhoea, constipation, bloating, and skin rashes. 

    Onchocerciasis, also called river blindness, is a worm that affects the skin and eyes. It causes symptoms such as skin rashes, severe itching, bumps under the skin, and visual impairment.

    FAQs

    Ivermectin can cause fever and rash. However, you may or may not develop a fever while using Ivermectin as everybody does not experience the same side-effects.

    The symptoms usually improve within two to three days after taking Ivermectin. If there is no improvement within 7 days of treatment, consult your doctor immediately.

    Ivermectin can be used for treating scabies only when prescribed by a doctor.

    No, it is not recommended to take Ivermectin daily. Take this medication as prescribed by your doctor.

    Ivermectin should be used with caution in patients with seizures or epilepsy. Consult a doctor before using Ivermectin to avoid unwanted side-effects.

    Ivermectin is used to treat parasitic infections. So, consult a doctor before using Ivermectin for any skin infection.

    No, Ivermectin is not available over the counter. It can only be taken if prescribed by a doctor. Take it only under the supervision of a healthcare professional.

    Available Medicines for

    Ivermectin

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