Ketoconazole+betamethasone
About
Ketoconazole+betamethasone belongs to a class of drugs called 'antifungal' primarily used to treat the skin's fungal infections. It minimizes the redness, itching, pain, and inflammation of the skin caused due to fungal infections. Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).
Ketoconazole+betamethasone contains Ketoconazole (antifungal) and betamethasone (steroid). Ketoconazole works by rupturing the fungal cell membrane's outer layer, which ultimately bursts the fungal cell's cellular content, leading to its death. On the other hand, Betamethasone works by acting inside skin cells and inhibiting the release of certain chemical messengers (histamine) that cause allergic symptoms like redness, itching, and skin swelling.
Apply this medicine in the dose and duration prescribed by your doctor. Some people may experience itching, pain, irritation, or burning sensation at the application site. Most of these side effects of Ketoconazole+betamethasone do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Ketoconazole+betamethasone can cause liver failure, so your doctor will monitor your liver function while you're taking Ketoconazole+betamethasone. If you are pregnant or a nursing mother, it is advised to consult a doctor before using the Ketoconazole+betamethasone. If you use Ketoconazole+betamethasone in topical form, avoid smoking or going near naked flames as Ketoconazole+betamethasone catches fire and burns quickly. Use of Ketoconazole+betamethasone is contraindicated in people with liver disease, asthma, sulfite allergy, an autoimmune disorder, and heart problems; inform your doctor before using Ketoconazole+betamethasone.
Uses of Ketoconazole+betamethasone
Medicinal Benefits
Ketoconazole+betamethasone is an antifungal that is primarily used to treat fungal infections. The fungal cell membranes are essential for their survival as they prevent unwanted substances into the cells and stop the leakage of cell contents. Ketoconazole is an antifungal that causes holes in the fungal cell membranes, thereby bursting its cellular content, ultimately killing fungi. Betamethasone is a steroid that acts inside skin cells and inhibits the release of certain chemical messengers (histamine) in the body that cause allergic symptoms like redness, itching, and swelling. This treats fungal infections and provides relief from cracking, burning, scaling, and itching of the skin caused due to conditions.
Directions for Use
Storage
Side Effects of Ketoconazole+betamethasone
- Dry skin
- Itching
- Skin redness
- Burning sensation
- Application Site Redness Of Skin
In-Depth Precautions and Warning
Drug Warnings
Avoid contact of Ketoconazole+betamethasone with nose, mouth, or eyes as it may irritate. If Ketoconazole+betamethasone accidentally comes in contact with these areas, rinse with water thoroughly. If you are pregnant, planning for pregnancy, or breastfeeding mother, you should consult a doctor before using Ketoconazole+betamethasone. If you use Ketoconazole+betamethasone, avoid smoking or going near naked flames as Ketoconazole+betamethasone catches fire and burns quickly. Tell your doctor before using Ketoconazole+betamethasone; if you have asthma, sulpha medicine allergy, an autoimmune disorder, or heart or liver problems, inform your doctor. Ketoconazole+betamethasone can cause serious harm to your liver that may result in a liver transplant or cause even death. Avoid using Ketoconazole+betamethasone for more than five days in children and on the face. Ketoconazole+betamethasone should not be used to treat fungal infections of the fingernails/toenails, prostate cancer, or Cushing’s syndrome. Ketoconazole+betamethasone could make your skin sensitive to the sunlight and cause sunburn more quickly, so try to avoid direct exposure to the sunlight. Apply sunscreen (SPF 30 or higher) whenever you go outdoors.
Drug Interactions
Drug-Drug Interactions: Ketoconazole+betamethasone may interact with drugs used to lower high blood pressure (metoprolol), pain killers (aspirin, ibuprofen), antianxiety drugs (alprazolam), laxatives (magnesium sulfate), blood thinners (warfarin), treat heartburn and acidity (omeprazole), immunosuppressant (cyclosporin), glucocorticoids (fluticasone, hydrocortisone), antifungal (fluconazole), blood cholesterol-lowering medicines (atorvastatin), bronchodilators (albuterol), blood thinners (warfarin), laxative (polyethylene glycol 3350).
Drug-Food Interactions: Ketoconazole+betamethasone may interact with caffeine-containing tea, coffee, cola, and energy drinks as it may increase the adverse effects of caffeine. Do not take marijuana with Ketoconazole+betamethasone as it may worsen the adverse effects of marijuana. Also, avoid consumption of alcohol with Ketoconazole+betamethasone as it may increase the risk of liver damage.
Drug-Disease Interactions: If you have diabetes, psoriasis, glaucoma, cataracts, adrenal gland, asthma, sulfite allergy, an autoimmune disorder, or heart or liver problems, inform your doctor before taking Ketoconazole+betamethasone.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consumption of alcohol while taking Ketoconazole+betamethasone as it may increase the risk of liver damage and cause adverse effects.
Pregnancy
cautionKetoconazole+betamethasone is a Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionKetoconazole+betamethasone is excreted in human milk and is given to a breastfeeding mother only if the doctor thinks benefits outweigh risks.
Driving
safe if prescribedKetoconazole+betamethasone usually does not affect your ability to drive or operate machinery.
Liver
cautionInform your doctor before receiving the Ketoconazole+betamethasone if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionInform your doctor before receiving the Ketoconazole+betamethasone if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
cautionKetoconazole+betamethasone is not recommended for children below one year as the safety and effectiveness were not established. Please consult a doctor before using Ketoconazole+betamethasone in children.
Habit Forming
Diet & Lifestyle Advise
- Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
- Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
- Do not scratch the affected skin, as it can spread the infection to other body parts.
- Avoid sharing towels, combs, bedsheets, shoes, or socks with others.
- Wash your bed sheets and towels regularly.
- Avoid taking Ketoconazole+betamethasone (oral form) with foods containing chocolate and caffeine, such as cocoa beans, tea, coffee, cola, and energy drinks, as it may increase the adverse effects of caffeine.
- Avoid alcohol intake with Ketoconazole+betamethasone (oral form) as it may cause adverse effects and increase the risk of liver damage.
Special Advise
- Before applying the Ketoconazole+betamethasone, clean and dry the affected area.
- Avoid contact of Ketoconazole+betamethasone with nose, mouth, or eyes. In case Ketoconazole+betamethasone comes in connection with these areas accidentally, rinse with water thoroughly.
- Do not wash the treated areas for a minimum of 3 hours after you apply the Ketoconazole+betamethasone.
- Use hand sanitisers regularly during fungal infection to avoid the unnecessary spread of the disease.
- Keep the affected area dry and free from contact with moisture or water.
Patients Concern
Disease/Condition Glossary
Fungal infection: Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). Ringworm is a common fungal infection of the skin or scalp that is contagious and causes a rash resembling a worm in a ring shape. Jock itch (also known as tinea cruris) is a fungal infection of the skin that causes an itchy, red rash in warm and moist areas of the body, such as the groin, buttocks, and inner thighs. Athlete's foot (also known as tinea pedis) is a fungal infection that usually starts between the toes, especially in people who have extremely sweaty feet and wear tight-fitting shoes. It occurs most commonly in athletes. It causes itching, burning, or stinging sensation due to a scaly rash. Seborrheic dermatitis is a skin condition that causes an itchy rash with dry, flaky scales on the skin that contains oil glands such as the scalp, face, back, and upper chest.
FAQs
You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola, and energy drinks while taking Ketoconazole+betamethasone in oral form (tablets) as it may increase the adverse effects of caffeine such as drowsiness, nervousness, or nausea.
Yes, Ketoconazole+betamethasone may cause skin reactions such as contact dermatitis (red, itchy skin rash caused by direct contact with a certain substance) as it contains stearyl alcohol and cetyl alcohol responsible for causing such skin reactions. However, if the irritation worsens or persists, please consult a doctor.
Prolonged use of Ketoconazole+betamethasone can cause severe liver damage and heart problems like life-threatening heart rate or heart rhythm problems. So, if you are having any heart or liver disease consult a doctor before using Ketoconazole+betamethasone.
You are recommended to use Ketoconazole+betamethasone for as long as your doctor has prescribed it. However, if the condition worsens or persists after 2 to 4 weeks of treatment with Ketoconazole+betamethasone, please consult a doctor.
You are recommended to apply makeup or sunscreen to the treated area of skin after a minimum of 20 minutes of using Ketoconazole+betamethasone.
No, you are not recommended to stop using Ketoconazole+betamethasone without consulting your doctor as it may cause recurring infection. Therefore, take Ketoconazole+betamethasone for as long as your doctor has prescribed it, and if you experience any difficulty while taking Ketoconazole+betamethasone, please consult your doctor.
Ketoconazole+betamethasone contains Ketoconazole (antifungal) and betamethasone (steroid). Ketoconazole works by rupturing the fungal cell membrane's outer layer, ultimately bursting the fungal cell's cellular content, leading to its death. On the other hand, Betamethasone works by acting inside skin cells and inhibiting the release of certain chemical messengers (histamine) that cause allergic symptoms like redness, itching, and skin swelling.
