Ketorolac+moxifloxacin
About
Ketorolac+moxifloxacin is an ophthalmic (for eye use) medication, primarily used to treat and prevent bacterial eye infections and itchy eyes caused by seasonal allergies. Ketorolac+moxifloxacin also relieves swelling, pain, and burning or stinging sensation after cataract surgery or corneal refractive surgery. A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids).
Ketorolac+moxifloxacin contains two medicines, namely: Ketorolac (non-steroidal anti-inflammatory drug (NSAID)) and Moxifloxacin (antibiotic). Ketorolac is a non-steroidal anti-inflammatory drug. It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the infected site. Moxifloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for the replication, transcription and repair of the DNA.
Your doctor will advise on how often you take Ketorolac+moxifloxacin based on your medical condition. Some common side effects of Ketorolac+moxifloxacin include blurred vision, watery eyes, burning/stinging sensation in the eye, and eye discomfort. These side effects do not require medical attention and gradually resolve over time.
Please do not use Ketorolac+moxifloxacin without consulting your doctor if you have any eye surgery, diabetes, asthma, nasal polyps, or eye problems like dry eye syndrome and corneal problems. Avoid touching the eyedropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. Avoid driving or operating machines since the administration of Ketorolac+moxifloxacin causes blurred vision for a while after using. If you are pregnant or a breastfeeding mother, please consult your doctor before using Ketorolac+moxifloxacin.
Uses of Ketorolac+moxifloxacin
Medicinal Benefits
Ketorolac+moxifloxacin treats and prevents bacterial eye infections and itchy eyes caused by seasonal allergies. It also relieves swelling, pain, and burning or stinging sensation after cataract surgery or corneal refractive surgery. It contains two medicines, namely: Ketorolac (NSAID) and Moxifloxacin (antibiotic). Ketorolac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking chemical messengers called 'prostaglandins' in your body to reduce pain and swelling. Moxifloxacin is a quinolone antibiotic. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for the replication, transcription, and repair of the DNA.
Directions for Use
Storage
Side Effects of Ketorolac+moxifloxacin
- Blurred vision
- Burning/stinging sensation of the eye
- Watery eyes
- Eye discomfort
In-Depth Precautions and Warning
Drug Warnings
Before using the Ketorolac+moxifloxacin, let your doctor know if have eye surgery, diabetes, asthma, nasal polyps, or eye problems like dry eye syndrome and corneal problems. Avoid touching the dropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. If you wear contact lenses, remove them while administering the medicine into the eye. It is advised to check with your doctor before using Ketorolac+moxifloxacin if you are pregnant or breastfeeding. Avoid driving or operating machines since the administration of Ketorolac+moxifloxacin may cause temporary blurred vision for a while.
Drug Interactions
Drug-Drug Interaction: Ketorolac+moxifloxacin may interact with blood thinners (clopidogrel, dabigatran, enoxaparin, and warfarin), pain killers (aspirin, naproxen, and ibuprofen), and corticosteroid drugs (prednisone).
Drug-Food Interaction: No drug-food interactions were found.
Drug-Disease Interaction: Brief your doctor if you have any eye problems like dry eye syndrome and corneal problems, allergic reactions to medicines or liver and kidney diseases before taking Ketorolac+moxifloxacin.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThere is limited information on how alcohol consumption affects Ketorolac+moxifloxacin. Please consult your doctor before starting.
Pregnancy
cautionPlease consult your doctor if you are planning to become pregnant or already pregnant before starting Ketorolac+moxifloxacin.
Breast Feeding
cautionIt is not known if Ketorolac+moxifloxacin passes into the breast milk. Please consult your doctor before starting Ketorolac+moxifloxacin if you are a lactating mother.
Driving
cautionKetorolac+moxifloxacin may cause side effects like blurry vision, which could affect your ability to drive. Do not drive or operate machinery in such cases. Drive only when you are alert and have a clear vision.
Liver
cautionLet your doctor know if you have any history of liver diseases. Your doctor will weigh the benefits and potential risks before prescribing Ketorolac+moxifloxacin.
Kidney
cautionLet your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Ketorolac+moxifloxacin.
Children
cautionKetorolac+moxifloxacin is not recommended in children below two years of age. The dose may have to be adjusted by your doctor depending upon the condition of the children's disease and age.
Habit Forming
Diet & Lifestyle Advise
- Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Ketorolac+moxifloxacin.
- Try to maintain good hygiene to keep your eyes clean and irritant-free.
- Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
- Wash your hands thoroughly and do not touch the dropper before using drops to avoid contamination.
- Know your allergy triggers, such as pollen, dust and other factors.
Special Advise
It is advised to reach out to your doctor if the bacterial infection symptoms persist or worsen after two weeks of treatment.
Patients Concern
Disease/Condition Glossary
Bacterial eye infection: A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids). A bacterial eye infection symptoms include red eyes, pain, swelling of the eyes, watery eyes, itching, and blurry vision. Some very common eye infections are Conjunctivitis (pink eye) and Stye.
Conjunctivitis: A condition caused by the inflammation and irritation of the eye's mucous membrane (conjunctiva).
Stye: Formation of a bump on the eyelid that happens when bacteria from the skin get into the hair follicle of an eyelash.
Allergy is an immune response produced by the body in response to 'allergens,' which release 'histamines' into the blood. Histamines are the chemicals released into the body due to this immune response and cause a stuffy nose, watery eyes, itching nose/throat etc.
FAQs
Ketorolac+moxifloxacin contains Ketorolac (NSAID) and Moxifloxacin (antibiotic). Ketorolac blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy. Moxifloxacin works by inhibiting bacterial DNA gyrase, an enzyme required for the replication, transcription, and repair of the DNA, leading to bacterial cell death. Collectively, Ketorolac+moxifloxacin helps in relieving and treating symptoms of bacterial eye infections.
If you use other eye ointments/drops along with Ketorolac+moxifloxacin, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any eye ointment.
Ketorolac+moxifloxacin can cause a blurry vision for some time in the beginning. Avoid driving and operating machinery in such cases until you feel better. If the effect persists longer, seek medical attention.
Avoid the contact of the dropper or tip with fingers, eyes, and eyelids when you use eye ointment or eye drops. Topical eye products, when contaminated by patients with eye diseases, bacterial keratitis (an infection of the cornea) and ocular infections (eye infections) may occur, which result in vision loss.
It is advised to remove your contact lens if you are wearing it while administering Ketorolac+moxifloxacin. Also, remember to wash your hands before and after administering the medicine to avoid contamination.
