Ketorolac+tramadol
About Ketorolac+tramadol
Ketorolac+tramadol belongs to the group of painkillers and analgesics used short-term to relieve moderate to severe pain. Pain is a sensation that occurs in response to external injury, stress, infection and travels as an impulse through body cells, producing an unpleasant feeling and alerting the body to act.
Ketorolac+tramadol contains Ketorolac and Tramadol. Ketorolac+tramadol works by reducing the production of inflammatory substances (prostaglandins) and thus, relieves the body of swelling and subsequent pain. Ketorolac+tramadol also blocks pain-producing nerve transmitters, thereby providing pain relief.
Take Ketorolac+tramadol as prescribed. Ketorolac+tramadol may cause certain common side effects such as stomach ache, nausea, vomiting, gas, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to any of the components of Ketorolac+tramadol. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Ketorolac+tramadol may cause dizziness, so drive only if you are alert. Avoid taking alcohol with Ketorolac+tramadol as it might lead to increased dizziness.
Uses of Ketorolac+tramadol
Medicinal Benefits
Ketorolac+tramadol is an analgesic that is used as a painkiller for short-term management of moderate to severe pain. Ketorolac+tramadol contains Ketorolac and Tramadol. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing the levels of inflammatory substances called prostaglandins. Prostaglandins are produced at the site of injury and cause inflammation and pain. Tramadol blocks the cellular reuptake of neurotransmitters (sensation-producing substances travelling through nerves) serotonin and noradrenaline, omitting pain impulses at the spinal level. Thus, Ketorolac+tramadol helps relieve pain.
Directions for Use
Storage
Side Effects of Ketorolac+tramadol
- Nausea
- Stomach ache
- Gas
- Diarrhoea
- Constipation
- Fatigue
- Dry mouth
- Dizziness
Drug Warnings
Ketorolac+tramadol should not be used in case of any known allergy to either of the components or to NSAID’s/opioids in general. Ketorolac+tramadol is not recommended for use in case of high risk or previous history of peptic ulcer disease, bleeding disorders, heart failure, asthma, IBD or if you have had any kind of stroke (even transient ischaemic stroke). Ketorolac+tramadol should be used with caution in patients with a known history of substance abuse (individual or within the family), diabetes mellitus, epilepsy, kidney disease, liver disease, arterial or thrombotic disorders, cardiovascular health disorders, mental health issues, asthma, emphysema, pancreatitis, gallbladder disease, bleeding disorders, peptic ulcers, IBD/IBS, enlarged prostate, rheumatoid arthritis, dry eye syndrome, hypertension, obesity, anaemia, nasal polyps (overgrowth in the nose), stroke and any disease-causing swelling in the feet and hands. Consult your doctor before using Ketorolac+tramadol during pregnancy or breastfeeding as it is not recommended for use in these states.
Drug Interactions
Drug-Drug Interactions: Ketorolac+tramadol may interact with other pain-killers (pentazocin, pentoxifylline, nalbuphine, butorphanol, anti-addiction drug (naltrexone), antihypertensives (captopril, lisinopril, losartan), diuretics (furosemide), mood stabiliser (lithium), DMARD (methotrexate), steroids (prednisolone), blood-thinners (clopidogrel, warfarin, enoxaparin), anti-gout drug (probenecid), anti-epileptic drugs (phenytoin, carbamazepine), psychoactive drugs (fluoxetine, alprazolam), anti-depressants (SSRI’s like citalopram, escitalopram), MAOI’s (selegiline, phenelzine, linezolid, methylene blue, moclobemide, procarbazine), heart medication (quinidine), anti-HIV drug (ritonavir), antifungals (itraconazole, ketoconazole), antibiotics (erythromycin).
Drug-Food Interactions: Ketorolac+tramadol may interact with high-fat foods and alcohol.
Drug-Disease Interactions: Ketorolac+tramadol should be used with caution in patients with a known history of substance abuse (individual or within the family), hypersensitivity disorder, diabetes mellitus, epilepsy, kidney disease, liver disease, arterial or thrombotic disorders, cardiovascular health disorders, mental health issues, asthma, emphysema, pancreatitis, gallbladder disease, bleeding disorders, peptic ulcers, IBD/IBS, enlarged prostate, rheumatoid arthritis, dry eye syndrome, hypertension, obesity, anaemia, nasal polyps (overgrowth in the nose), stroke and any disease causing a swelling in the feet and hands.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are advised not to take alcohol with Ketorolac+tramadol as it can make you dizzier. Please consult your doctor if you have any concerns.
Pregnancy
cautionKetorolac+tramadol is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.
Breast Feeding
cautionKetorolac+tramadol is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.
Driving
cautionKetorolac+tramadol may cause dizziness and drowsiness, which may affect your ability to drive. Therefore, drive only if you are alert.
Liver
cautionExercise caution before using Ketorolac+tramadol in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
cautionExercise caution before using Ketorolac+tramadol in case of kidney problems. Please consult your doctor to address any concerns.
Children
unsafeKetorolac+tramadol is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Stay hydrated by drinking plenty of water.
- Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. Limit your intake of sweets and sugars as these can worsen inflammation.
- Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
- Try meditation and deep breathing to reduce overall stress and pain.
- Stop smoking as smoking is known to worsen pain conditions.
- Engage in mild physical exercise daily and keep your body active.
Special Advise
- In case you miss a dose of Ketorolac+tramadol, skip it and resume when it is time for the second dose only. Do not ever take a double dose.
- It is very difficult to overdose on Ketorolac+tramadol however, if you accidentally take extra doses of Ketorolac+tramadol, please inform your doctor or go to a hospital immediately. Some of the symptoms of an overdose can be blurred vision, shortness of breath, difficulty in speaking, severe headache, unusual tiredness, fainting and or ringing in the ears.
- Avoid taking antacids within 2-3 hours of Ketorolac+tramadol.
Patients Concern
Disease/Condition Glossary
Pain: Pain is a sensation that occurs in response to external injury, stress, infection and travels as an impulse through body cells, producing an unpleasant feeling and alerting the body to act. Pain relief in pharmacological terms is called analgesia. Various neurotransmitters and their equilibrium are instrumental in producing pain sensation.
FAQs
Ketorolac+tramadol works by reducing the levels of prostaglandins (inflammatory markers), blocking the impulses of pain, relieving the body of inflammation and reducing the sensation of pain.
Ketorolac+tramadol should be used with caution in those suffering from asthma. Consult your doctor before use if you have asthma.
While Ketorolac+tramadol is safe for treating pain, Ketorolac+tramadol is not meant for long-term use because it can damage the kidneys and/or cause internal bleeding if used for longer durations.
No, Ketorolac+tramadol is not indicated as a painkiller during labour and delivery as it may cause uterine bleeding.
Ketorolac+tramadol is not indicated to treat headaches due to migraines. It is best to get your headache checked by a professional. Please consult your doctor in case of any concerns.
