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Lidocaine+metronidazole+sucralfate

About

Lidocaine+metronidazole+sucralfate belongs to a class of medications called 'anorectal preparations' primarily used in the treatment of anal fissures (small tear in the anus lining), fistula (abnormal skin opening near the anus) and piles (inflamed and swollen veins in the rectum). Anorectal disorders occur at the junction of the anal canal and the rectum, including haemorrhoids, abscesses, fistula, fissures, anal itching and warts. It is characterized by the accumulation of veins at the anus with frequent mucus and bleeding while straining for stool passage. 

Lidocaine+metronidazole+sucralfate is a combination of three drugs, namely: Lidocaine (local anaesthetic), Metronidazole (antibiotic) and Sucralfate (protectant). Lidocaine is a local anaesthetic that decreases pain sensation by preventing pain signals transmission from nerves to the brain.  Metronidazole belongs to the class of antibiotics that prevents bacterial infection caused due to exposed skin surface of the anus. Sucralfate belongs to the class of protectants that form a protective layer over the affected area of skin, thereby preventing pain, burning sensation and inflammation in the anus. Thus together Lidocaine+metronidazole+sucralfate promotes the healing of fissures, helps in forming new healthy skin and minimises infection and pain around the anal canal. 

Lidocaine+metronidazole+sucralfate is for external use only. Use Lidocaine+metronidazole+sucralfate as prescribed by your doctor. Avoid contact of Lidocaine+metronidazole+sucralfate with nose, ears, mouth or eyes. In case Lidocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. Your doctor will advise you how often you take Lidocaine+metronidazole+sucralfate based on your medical condition. In some cases, you may experience a skin rash, mild irritation, tingling or burning sensation. Most of these side effects of Lidocaine+metronidazole+sucralfate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Lidocaine+metronidazole+sucralfate or any other medicines, please tell your doctor. Lidocaine+metronidazole+sucralfate is for external use only. Avoid contact of Lidocaine+metronidazole+sucralfate with nose, ears, mouth or eyes. In case Lidocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, please inform your doctor before taking Lidocaine+metronidazole+sucralfate. Do not apply Lidocaine+metronidazole+sucralfate in large amounts or use it for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Do not swallow Lidocaine+metronidazole+sucralfate. In case of accidental swallowing, please consult a doctor immediately. If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Lidocaine+metronidazole+sucralfate.

Uses of Lidocaine+metronidazole+sucralfate

Anorectal diseases (piles, fistula, fissure)

Medicinal Benefits

Lidocaine+metronidazole+sucralfate is a combination of three drugs, namely: Lidocaine, Metronidazole, and Sucralfate. Lidocaine belongs to the class of local anesthetics that decreases pain sensation by preventing the transmission of pain signals from nerves to the brain. Metronidazole belongs to the class of antibiotics that works by damaging the DNA (genetic material) of bacteria and protozoa and kills them. Thereby prevents infection in the anal region. Sucralfate belongs to the class of protectants that works by forming a protective layer over the affected area of skin and prevents pain, irritation, or burning sensation in the anus. Thereby, promotes the healing of fissures and the formation of new healthy skin.

Directions for Use

Use Lidocaine+metronidazole+sucralfate as prescribed by your doctor. Apply a small amount of Lidocaine+metronidazole+sucralfate on the clean and dry affected area of the skin of the anus. Lidocaine+metronidazole+sucralfate is only for external use. Avoid contact of Lidocaine+metronidazole+sucralfate with nose, mouth or eyes. In case Lidocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Lidocaine+metronidazole+sucralfate.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lidocaine+metronidazole+sucralfate

  • Skin rash
  • Mild irritation
  • Tingling
  • Burning sensation
  • Diarrhoea
  • Dry mouth

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Lidocaine+metronidazole+sucralfate or any other medicines, please tell your doctor. Lidocaine+metronidazole+sucralfate is for external use only. Avoid contact of Lidocaine+metronidazole+sucralfate with nose, ears, mouth, or eyes. In case Lidocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, please inform your doctor before taking Lidocaine+metronidazole+sucralfate. Do not apply Lidocaine+metronidazole+sucralfate on cuts, wounds, grazes, or raw or blistered skin. You are recommended to avoid rubbing, scratching, or exposure to extreme cold and hot until the anesthetic effect has worn off. Avoid using Lidocaine+metronidazole+sucralfate in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Do not swallow Lidocaine+metronidazole+sucralfate. In case of accidental swallowing, please consult a doctor immediately. If you have kidney or liver disease, diabetes, or blood disorders, inform your doctor before taking Lidocaine+metronidazole+sucralfate.

Drug Interactions

Drug-Drug Interaction: Lidocaine+metronidazole+sucralfate may have interaction with medicines to treat irregular heartbeat (amiodarone, tocainide, mexiletine), high blood pressure-lowering medicines (propranolol, metoprolol), medicines to treat stomach ulcers or heartburn (cimetidine), tuberculosis vaccine, vitamin (ascorbic acid), blood thinners (warfarin, dicoumarin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Lidocaine+metronidazole+sucralfate.

Drug-Drug Interactions Checker List:

  • AMIODARONE
  • MEXILETINE
  • PROPRANOLOL
  • METOPROLOL
  • CIMETIDINE
  • ASCORBIC ACID
  • WARFARIN
  • TOCAINIDE
  • TUBERCULOSIS VACCINE
  • DICOUMAROL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of Lidocaine+metronidazole+sucralfate with alcohol is unknown. Please consult a doctor before consuming alcohol while using Lidocaine+metronidazole+sucralfate.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor if you are pregnant or planning for pregnancy. Lidocaine+metronidazole+sucralfate is given to pregnant women only if the doctor thinks benefits outweigh risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Lidocaine+metronidazole+sucralfate is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      safe if prescribed

      Lidocaine+metronidazole+sucralfate usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of Lidocaine+metronidazole+sucralfate in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of Lidocaine+metronidazole+sucralfate in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      caution

      Lidocaine+metronidazole+sucralfate should be used in children only if prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Drink plenty of fluids to prevent constipation.
    • Take fiber supplements and fiber-rich foods such as raw fruits and vegetables.
    • Take a sitz bath (a warm water bath covering hips and buttocks) to relax anal muscles, increase blood flow to the anorectal area and relieve irritation.
    • Avoid straining during bowel movements as it may create pressure and lead to the opening of a healing tear or cause a new tear.

    Special Advise

    Follow WASH regimen for anorectal diseases like piles:

    • W stands for a warm sitz bath for 10 minutes.
    • A stands for analgesic and painkiller.
    • S stands for stool softener.
    • H stands for hemorrhoidal cream.  

    Patients Concern

    Disease/Condition Glossary

    Anal Fissure: It is a small cut or tear in the lining of the anus. Sometimes, the crack may be so deep that it exposes the muscle tissue underneath. It occurs mostly when passing hard or large stools, diarrhea, or chronic constipation. The crack in the skin leads to severe pain and bleeding during and after bowel movements. Anal fissure symptoms include sharp pain in the anal region during bowel movements, itching or burning sensation in the anal region, a visible tear in the skin around the anus, streaks of blood on stools, a skin tag or small lumps or skin next to the tear.

    Piles: It occurs when anus tissue and vein become inflamed and swollen. The size of piles can vary from small to large either found inside or outside the anus. Piles can occur due to many reasons like chronic constipation, chronic diarrhea, pregnancy, lifting heavy weights, or straining when passing a stool.

    Anal Fistula: It is an abnormal connection between the inside of the anal canal and the skin around the anus resulting from an injury or surgery. Infection or inflammation can also cause a fistula to form. 

    FAQs

    Lidocaine+metronidazole+sucralfate contains Lidocaine, Metronidazole and Sucralfate. Lidocaine is a local anaesthetic that decreases pain sensation by preventing pain signals transmission from nerves to the brain. Metronidazole is an antibiotic that minimizes the spread of spreading the bacterial infection around the anus skin region due to swelling and inflamed veins. Sucralfate is a protectant that works by forming a protective layer over the affected area of skin and prevents pain, irritation or burning sensation in the anus. Thereby, promotes healing of anus skin and formation of new healthy skin.

    Yes, Lidocaine+metronidazole+sucralfate may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor. Also, avoid using and consult a doctor if you experience increased irritation or redness.

    You are recommended to avoid foods rich in oil content and spicy foods for effective results while taking Lidocaine+metronidazole+sucralfate.

    Yes, Lidocaine+metronidazole+sucralfate provides relief from pain caused by an anal fissure. Lidocaine+metronidazole+sucralfate contains lidocaine, a local anaesthetic that decreases pain sensation by causing numbness around the affected area.

    Do not stop using Lidocaine+metronidazole+sucralfate without consulting your doctor even if you find symptomatic relief as discontinuing suddenly may worsen the condition. Therefore, complete the full course of Lidocaine+metronidazole+sucralfate as your doctor has prescribed it, and if you experience any difficulty while using Lidocaine+metronidazole+sucralfate, please consult your doctor.

    Lidocaine+metronidazole+sucralfate is not addictive in nature.

    No, Lidocaine+metronidazole+sucralfate should not be used for broken skin, open wounds or cuts.

    Available Medicines for

    Lidocaine+metronidazole+sucralfate

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