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Lignocaine+metronidazole+sucralfate

About

Lignocaine+metronidazole+sucralfate belongs to a class of medications called 'anorectal preparations' primarily used in the treatment of anal fissure (small tear in the anus lining), fistula (abnormal skin opening near the anus) and piles (inflamed and swollen veins in rectum). Anorectal disorders occur at the junction of the anal canal and the rectum, including haemorrhoids, abscesses, fistula, fissures, anal itching and warts. It is characterized by the accumulation of veins at the anus with frequent mucus and bleeding while straining for stool passage. 

Lignocaine+metronidazole+sucralfate is a combination of three drugs, namely: Lignocaine (local anaesthetic), Metronidazole (antibiotic) and Sucralfate (protectant). Lignocaine is a local anaesthetic that decreases pain sensation by preventing pain signals transmission from nerves to the brain. Metronidazole belongs to the class of antibiotics that prevents bacterial infection caused due to exposed skin surface of the anus. Sucralfate belongs to the class of protectants that form a protective layer over the affected area of skin, thereby preventing pain, burning sensation and inflammation in the anus. Thus together Lignocaine+metronidazole+sucralfate promotes healing of fissures, helps in forming new healthy skin and minimizing infection and pain around the anal canal. 

Lignocaine+metronidazole+sucralfate is for external use only. Avoid contact of Lignocaine+metronidazole+sucralfate with nose, ears, mouth or eyes. In case Lignocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. Your doctor will advise you how often you need to use Lignocaine+metronidazole+sucralfate based on your medical condition. In some cases, you may experience a skin rash, mild irritation, tingling or burning sensation. Most of these side effects of Lignocaine+metronidazole+sucralfate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Lignocaine+metronidazole+sucralfate or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, please inform your doctor before taking Lignocaine+metronidazole+sucralfate. Do not apply Lignocaine+metronidazole+sucralfate in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Do not swallow Lignocaine+metronidazole+sucralfate. In case of accidental swallowing, please consult a doctor immediately. If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Lignocaine+metronidazole+sucralfate.

Uses of Lignocaine+metronidazole+sucralfate

Piles, fistula, anal fissure

Medicinal Benefits

Lignocaine+metronidazole+sucralfate contains Lignocaine, Metronidazole and Sucralfate. Lignocaine is a local anaesthetic that decreases pain sensation by preventing the transmission of pain signals from nerves to the brain. Metronidazole is an antibiotic that works by damaging the DNA (genetic material) of bacteria and protozoa, thus kills them. Thereby preventing infection in the anal region. Sucralfate belongs to the class of protectants that works by forming a protective layer over the affected area of skin and prevents pain, irritation or burning sensation in the anus. Thereby promoting the healing of fissures and the formation of new healthy skin.

Directions for Use

Use Lignocaine+metronidazole+sucralfate as prescribed by your doctor. Apply a small amount of Lignocaine+metronidazole+sucralfate on the clean and dry affected area of the skin of the anus. Lignocaine+metronidazole+sucralfate is only for external use. Avoid contact of Lignocaine+metronidazole+sucralfate with nose, mouth or eyes. In case Lignocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Lignocaine+metronidazole+sucralfate.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lignocaine+metronidazole+sucralfate

  • Skin rash
  • Mild irritation
  • Tingling
  • Burning sensation

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Lignocaine+metronidazole+sucralfate or any other medicines, please tell your doctor. Lignocaine+metronidazole+sucralfate is for external use only. Avoid contact of Lignocaine+metronidazole+sucralfate with nose, ears, mouth or eyes. In case Lignocaine+metronidazole+sucralfate comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, please inform your doctor before taking Lignocaine+metronidazole+sucralfate. Do not apply Lignocaine+metronidazole+sucralfate on cuts, wounds, grazes, raw or blistered skin. You are recommended to avoid rubbing, scratching, or exposure to extreme cold and heat until the anaesthetic effect has worn off. Avoid using Lignocaine+metronidazole+sucralfate in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Do not swallow Lignocaine+metronidazole+sucralfate. In case of accidental swallowing, please consult a doctor immediately. If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Lignocaine+metronidazole+sucralfate.

Drug Interactions

Drug-Drug Interaction: Lignocaine+metronidazole+sucralfate may have interaction with medicines to treat irregular heartbeat (amiodarone, tocainide, mexiletine), high blood pressure-lowering medicines (propranolol, metoprolol), medicines to treat stomach ulcers or heartburn (cimetidine), tuberculosis vaccine, blood thinners (warfarin, dicoumarol).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Lignocaine+metronidazole+sucralfate.

Drug-Drug Interactions Checker List:

  • AMIODARONE
  • MEXILETINE
  • PROPRANOLOL
  • METOPROLOL
  • CIMETIDINE
  • WARFARIN
  • TOCAINIDE
  • TUBERCULOSIS VACCINE
  • DICOUMAROL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of Lignocaine+metronidazole+sucralfate with alcohol is unknown. Please consult a doctor before consuming alcohol while using Lignocaine+metronidazole+sucralfate.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor if you are pregnant or planning for pregnancy. Lignocaine+metronidazole+sucralfate is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Lignocaine+metronidazole+sucralfate is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      safe if prescribed

      Lignocaine+metronidazole+sucralfate usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of Lignocaine+metronidazole+sucralfate in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of Lignocaine+metronidazole+sucralfate in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      caution

      Lignocaine+metronidazole+sucralfate should be used in children only if prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Drink plenty of fluids to prevent constipation.
    • Take fibre supplements and fibre-rich foods such as raw fruits and vegetables.
    • Take a sitz bath (a warm water bath covering hips and buttocks) to relax anal muscles. It helps increase blood flow to the anorectal area and relieves irritation.
    • Avoid straining during bowel movements as it may create pressure and lead to the opening of healing tears or cause a new tear.

    Special Advise

    Follow WASH regimen for anorectal diseases like piles:

    • W stands for a warm sitz bath for 10 minutes.
    • A stands for analgesic and painkiller.
    • S stands for stool softener.
    • H stands for hemorrhoidal cream. 

    Patients Concern

    Disease/Condition Glossary

    Anal Fissure: It is a small cut or tears in the lining of the anus. Sometimes, the crack may be so deep that it exposes the muscle tissue underneath. It occurs mostly when passing hard or large stools, diarrhoea or chronic constipation. The crack in the skin leads to severe pain and bleeding during and after bowel movements. Anal fissure symptoms include sharp pain in the anal region during bowel movements, itching or burning sensation in the anal region, a visible tear in the skin around the anus, streaks of blood on stools, a skin tag or small lumps or skin next to the tear.

    Piles: It occurs when anus tissue and vein becomes inflamed and swollen. The size of piles can vary from small to large, either found inside or outside the anus. Piles can occur due to many reasons like chronic constipation, chronic diarrhoea, pregnancy, lifting heavy weights or straining when passing a stool.

    Anal Fistula: It is an abnormal connection between the inside of the anal canal and the skin around the anus resulting from an injury or surgery. Infection or inflammation can also cause a fistula to form.

    FAQs

    Lignocaine+metronidazole+sucralfate contains Lignocaine, Metronidazole and Sucralfate. Lignocaine decreases pain sensation by preventing pain signals transmission from nerves to the brain. Metronidazole minimizes the spread of bacterial infection around the anus skin region due to swelling and inflamed veins. Sucralfate is a protectant that works by forming a protective layer over the affected area of skin and prevents pain, irritation or burning sensation in the anus. Thereby promoting healing of anus skin and the formation of new healthy skin.

    Lignocaine+metronidazole+sucralfate may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor. Also, avoid using and consult a doctor if you experience increased irritation or redness.

    You are recommended to avoid foods rich in oil content and spicy foods for effective results while taking Lignocaine+metronidazole+sucralfate.

    Yes, Lignocaine+metronidazole+sucralfate provides relief from pain caused by an anal fissure. Lignocaine+metronidazole+sucralfate contains lignocaine, a local anaesthetic that decreases pain sensation by causing numbness around the affected area.

    Do not stop using Lignocaine+metronidazole+sucralfate without consulting your doctor even if you find symptomatic relief as discontinuing suddenly may worsen the condition. Therefore, complete the full course of Lignocaine+metronidazole+sucralfate as your doctor has prescribed it, and if you experience any difficulty while using Lignocaine+metronidazole+sucralfate, please consult your doctor.

    No, Lignocaine+metronidazole+sucralfate should not be used for external wounds. Please consult a doctor so that appropriate medication is prescribed to treat external wounds.

    Available Medicines for

    Lignocaine+metronidazole+sucralfate

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