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Losartan+s Amlodipine

About

Losartan+s Amlodipine belongs to the class of anti-hypertensive drugs, primarily used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases. Losartan+s Amlodipine lowers the blood pressure by widening and relaxing blood vessels. 

Losartan+s Amlodipine is a fixed-dose combination composed of two medicines, namely, Losartan and S-amlodipine. Losartan belongs to a group of drugs called angiotensin II receptor antagonists. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Losartan is also used to treat stroke and slow down kidney damage in people with type 2 diabetes. S-amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease. 

Take Losartan+s Amlodipine as prescribed. Your doctor will decide the dosage based on your medical condition. In some cases, Losartan+s Amlodipine can cause side effects like ankle swelling, headache, flushing (feeling warmth in the face, ears, neck, and trunk), dizziness, tiredness, palpitations (irregular heartbeat), upset stomach, and hyperkalemia (increased potassium levels in the blood), blurred vision, difficulty in breathing. Most of these side effects of Losartan+s Amlodipine do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Losartan+s Amlodipine or any other medicines, please inform your doctor. Before taking Losartan+s Amlodipine, let your doctor know if you have any kidney or liver problems or severe dehydration. Pregnant or breastfeeding women should also consult their doctor before taking it. It is advised to complete the prescribed course, even if you feel better. Please do not stop taking Losartan+s Amlodipine on your own, as it may lead to the recurrence of symptoms or worsen the condition. Do not consume alcohol with Losartan+s Amlodipine as it may increase the risk of low blood pressure. Avoid potassium supplements with Losartan+s Amlodipine as it may lead to high potassium levels in the blood. Losartan+s Amlodipine used caution with coronary artery diseases, aortic stenosis.

Uses of Losartan+s Amlodipine

High blood pressure (hypertension).

Medicinal Benefits

Losartan+s Amlodipine is an anti-hypertensive drug that treats high blood pressure (hypertension). Losartan+s Amlodipine lowers the blood pressure by widening and relaxing blood vessels. Losartan+s Amlodipine consists of two medicines, namely: Losartan and S-amlodipine. Losartan is an angiotensin II receptor antagonist. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Losartan is also used to treat stroke and slow down kidney damage in people with type 2 diabetes. S-amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease.

Directions for Use

Take Losartan+s Amlodipine with or without food as prescribed by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Losartan+s Amlodipine

  • Ankle swelling
  • Headache 
  • Flushing (feeling warmth in the face, ears, neck, and trunk)
  • Dizziness
  • Tiredness
  • Palpitations (irregular heartbeat)
  • Upset stomach
  • Hyperkalemia (increased potassium levels in the blood)
  • Blurred vision
  • Difficulty in breathing.

In-Depth Precautions and Warning

Drug Warnings

If you are known to be allergic to Losartan+s Amlodipine or any other medicines, please inform your doctor. Before taking Losartan+s Amlodipine, let your doctor know if you have any kidney or liver problems or severe dehydration. Pregnant or breastfeeding women should also consult their doctor before taking it. It is advised to complete the prescribed course, even if you feel better. Please do not stop taking Losartan+s Amlodipine on your own, as it may lead to the recurrence of symptoms or worsen the condition. Do not consume alcohol with Losartan+s Amlodipine as it may increase the risk of low blood pressure. Avoid potassium supplements with Losartan+s Amlodipine as it may lead to high potassium levels in the blood. Losartan+s Amlodipine used caution with coronary artery diseases, aortic stenosis, cardiogenic shock, and congestive heart failure.

Drug Interactions

Drug-Drug Interaction: Losartan+s Amlodipine may interact with other blood pressure treating medicines (Lisinopril, Ramipril, benazepril, aliskiren), pain killers (aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, hydrocodone), heart-related medicines (metoprolol, nitroglycerin), high cholesterol treating drugs (simvastatin), fluid retention drugs (hydrochlorothiazide), drugs treating impotence (sildenafil), anti-diabetics (insulin), anti-TB (rifampicin).

Drug-Food Interaction: Minimize high potassium foods intake and avoid over the counter potassium supplements, grapefruit, or juice.

Drug-Disease Interaction: People with low blood pressure, heart, kidney, or liver problems or severe dehydration, hyperkalemia (high potassium levels in the blood), and diabetes should consult the doctor before taking Losartan+s Amlodipine.

Drug-Drug Interactions Checker List:

  • LISINOPRIL
  • RAMIPRIL
  • BENAZEPRIL
  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • DICLOFENAC
  • INDOMETHACIN
  • MELOXICAM
  • HYDROCODONE
  • METOPROLOL
  • NITROGLYCERIN
  • SIMVASTATIN
  • HYDROCHLOROTHIAZIDE
  • SILDENAFIL
  • ALISKIREN
  • RIFAMPICIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      It is unsafe to consume alcohol, since alcohol consumption with Losartan+s Amlodipine may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

    • Safety Warning

      Pregnancy

      unsafe

      Losartan+s Amlodipine is not recommended and unsafe in pregnancy. It can affect and harm the baby. Consult your doctor before taking Losartan+s Amlodipine if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Losartan+s Amlodipine.

    • Safety Warning

      Breast Feeding

      caution

      There is no evidence on how Losartan+s Amlodipine affects breastfeeding. Please consult your doctor before taking Losartan+s Amlodipine if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      Losartan+s Amlodipine may cause side effects like dizziness, headaches, nausea, or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before taking Losartan+s Amlodipine. The dosage will be initiated in lower doses and will be further increased in patients with liver diseases.

    • Safety Warning

      Kidney

      caution

      Losartan+s Amlodipine consists of Losartan drug, which may affect the kidney functioning. Hence it is advised to seek doctor advice before starting Losartan+s Amlodipine if you have kidney problems.

    • Safety Warning

      Children

      caution

      It is not recommended for children below six years. However, for children above six years, give Losartan+s Amlodipine in doses as prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Reduce sodium intake in your diet to maintain your blood pressure.
    • Eat natural and healthy foods by cutting down on high on sodium processed foods.
    • Lose those extra pounds, since being obese can be a risk factor for hypertension.
    • Exercise regularly to maintain good heart health.
    • Avoid smoking and alcohol intake.
    • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.

    Special Advise

    • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor. A low salt/sodium diet and regular exercise are recommended along with Losartan+s Amlodipine for effective results.

    Patients Concern

    Disease/Condition Glossary

    Blood pressure/Hypertension: Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

    FAQs

    Losartan+s Amlodipine is a fixed-dose combination composed of two medicines, namely, Losartan and S-amlodipine. Losartan belongs to a group of drugs called angiotensin II receptor antagonists. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Losartan is also used to treat stroke and slow down kidney damage in people with type 2 diabetes. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease. 

    Losartan+s Amlodipine causes common side effects like ankle swelling, headache, flushing (feeling warmth in the face, ears, neck, and trunk), dizziness, tiredness, palpitations (irregular heartbeat), upset stomach and hyperkalemia (increased potassium levels in the blood), blurred vision, difficulty in breathing.

    Losartan+s Amlodipine is not recommended in pregnancy. It can affect and harm the baby. Consult your doctor before taking Losartan+s Amlodipine if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Losartan+s Amlodipine.

    Do not stop using Losartan+s Amlodipine even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

    No, Losartan+s Amlodipine can cause high levels of potassium in the blood leading to hyperkalemia. Hence it is not recommended to use potassium supplements along with Losartan+s Amlodipine. However, consult your doctor if you are already taking other medicines before starting Losartan+s Amlodipine.

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    Losartan+s Amlodipine

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